Apoptosis of leukocytes as a marker of neutrophil-endotheliocyte interaction in coronary heart disease

We studied the mechanism of interaction of peripheral blood neutrophils with endothelial cells (expression of cell adhesion molecules and production of NO) and the role of neutrophil apoptosis in the development of endothelial dysfunction. The effects of mitochondrial dysfunction of neutrophils on t...

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Bibliographic Details
Published in:	Bulletin of experimental biology and medicine Vol. 144; no. 1; pp. 39 - 41
Main Authors:	Salmina, A B, Shul'man, V A, Nikulina, S Yu, Trufanova, L V, Fursov, A A, But'yanov, P A, Kuskaev, A P, Bol'shakova, E V, Kotlovskii, M Yu
Format:	Journal Article
Language:	English
Published:	United States Springer Nature B.V 01-07-2007
Subjects:	Apoptosis Cell Communication - physiology Coronary Disease - blood Coronary Disease - physiopathology Endothelial Cells - physiology Humans Leukocytes - cytology Male Middle Aged Neutrophils - physiology Nitric Oxide - blood Platelet Endothelial Cell Adhesion Molecule-1 - biosynthesis
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Summary:	We studied the mechanism of interaction of peripheral blood neutrophils with endothelial cells (expression of cell adhesion molecules and production of NO) and the role of neutrophil apoptosis in the development of endothelial dysfunction. The effects of mitochondrial dysfunction of neutrophils on the development of apoptosis of these cells after their interaction with endothelial cells were analyzed.
Bibliography:	ObjectType-Article-2 SourceType-Scholarly Journals-1 ObjectType-Feature-1 content type line 23 ObjectType-Article-1 ObjectType-Feature-2
ISSN:	0007-4888 1573-8221
DOI:	10.1007/s10517-007-0248-y