Search Results - "Bussink, Anton P"

Suboptimal Viral Suppression Rates Among HIV-Infected Children in Low- and Middle-Income Countries: A Meta-analysis by Boerma, Ragna S., Boender, T. Sonia, Bussink, Anton P., Calis, Job C. J., Bertagnolio, Silvia, de Wit, Tobias F. Rinke, van Hensbroek, Michael Boele, Sigaloff, Kim C.E.

“…Background. The 90-90-90 goal to achieve viral suppression in 90% of all human immunodeficiency virus (HIV)-infected people on antiretroviral treatment (ART)…”
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Evolution of Mammalian Chitinase(-Like) Members of Family 18 Glycosyl Hydrolases by Bussink, Anton P, Speijer, Dave, Aerts, Johannes M. F. G, Boot, Rolf G

“…Family 18 of glycosyl hydrolases encompasses chitinases and so-called chi-lectins lacking enzymatic activity due to amino acid substitutions in their active…”
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Characterization of human phagocyte-derived chitotriosidase, a component of innate immunity by van Eijk, Marco, van Roomen, Cindy P. A. A., Renkema, G. Herma, Bussink, Anton P., Andrews, Laura, Blommaart, Edward F. C., Sugar, Alan, Verhoeven, Arthur J., Boot, Rolf G., Aerts, Johannes M. F. G.

“…Man has been found to produce highly conserved chitinases. The most prominent is the phagocyte-derived chitotriosidase, the plasma levels of which are markedly…”
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Marked Differences in Tissue-specific Expression of Chitinases in Mouse and Man by Boot, Rolf G, Bussink, Anton P, Verhoek, Marri, de Boer, Piet A.J, Moorman, Antoon F.M, Aerts, Johannes M.F.G

“…Two distinct chitinases have been identified in mammals: a phagocyte-specific enzyme named chitotriosidase and an acidic mammalian chitinase (AMCase) expressed…”
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Common G102S polymorphism in chitotriosidase differentially affects activity towards 4-methylumbelliferyl substrates by Bussink, Anton P, Verhoek, Marri, Vreede, Jocelyne, Ghauharali-van der Vlugt, Karen, Donker-Koopman, Wilma E, Sprenger, Richard R, Hollak, Carla E, Aerts, Johannes M.F.G, Boot, Rolf G

“…Chitotriosidase (CHIT1) is a chitinase that is secreted by activated macrophages. Plasma chitotriosidase activity reflects the presence of lipid-laden…”
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A single histidine residue modulates enzymatic activity in acidic mammalian chitinase by Bussink, Anton P., Vreede, Jocelyne, Aerts, Johannes M.F.G., Boot, Rolf G.

“…Mammals express two active chitinases, chitotriosidase and AMCase. Only AMCase displays an extremely acidic pH optimum, consistent with its observed presence…”
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Health Indicators of Pregnant Women in Tonkolili District, Rural Sierra Leone by Bussink-Voorend, Daphne, Bussink, Anton P., Falama, Abdul M., Stekelenburg, Jelle

“…Despite having reported one of the highest maternal mortality ratios and neonatal mortality rates in the world, surprisingly little is known about the general…”
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N-Azidoacetylmannosamine-mediated chemical tagging of gangliosides by Bussink, Anton P., van Swieten, Paul F., Ghauharali, Karen, Scheij, Saskia, van Eijk, Marco, Wennekes, Tom, van der Marel, Gijs A., Boot, Rolf G., Aerts, Johannes M.F.G., Overkleeft, Herman S.

“…Peracetylated N-α-azidoacetylmannosamine (Ac4ManNAz) is metabolized by cells to CMP-azidosialic acid. It has been demonstrated previously that in this way…”
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Biomarkers for lysosomal storage disorders: identification and application as exemplified by chitotriosidase in Gaucher disease by Aerts, Johannes M, Van Breemen, Marielle J, Bussink, Anton P, Ghauharali, Karen, Sprenger, Richard, Boot, Rolf G, Groener, Johanna E, Hollak, Carla E, Maas, Mario, Smit, Suzanne, Hoefsloot, Huub C, Smilde, Age K, Vissers, Johannes PC, De Jong, Sheryas, Speijer, Dave, De Koster, Chris G

“…A biomarker is an analyte that indicates the presence of a biological process linked to the clinical manifestations and outcome of a particular disease. An…”
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Detection of chitinase activity by 2-aminobenzoic acid labeling of chito-oligosaccharides by Ghauharali-van der Vlugt, Karen, Bussink, Anton P., Groener, Johanna E.M., Boot, Rolf G., Aerts, Johannes M.F.G.

“…Chitinases are hydrolases capable of hydrolyzing the abundant natural polysaccharide chitin. Next to artificial fluorescent substrates, more physiological…”
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Human acidic mammalian chitinase erroneously known as eosinophil chemotactic cytokine is not the ortholog of mouse YM1 by Boot, Rolf G, Bussink, Anton P, Aerts, Johannes M F G

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The Biology of the Gaucher Cell: The Cradle of Human Chitinases by Bussink, Anton P., van Eijk, Marco, Renkema, G. Herma, Aerts, Johannes M., Boot, Rolf G.

“…Gaucher disease (GD) is the most common lysosomal storage disorder and is caused by inherited deficiencies of glucocerebrosidase, the enzyme responsible for…”
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Pancreatic-type ribonuclease 1 gene duplications in rat species by Dubois, Jean-Yves F, Jekel, Peter A, Mulder, Patty P M F A, Bussink, Anton P, Catzeflis, François M, Carsana, Antonella, Beintema, Jaap J

“…Mammalian pancreatic-type ribonucleases (RNases) 1 represent single-copy genes in the genome of most investigated mammalian species, including Mus musculus and…”
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