Search Results - "Busse, Johanna"
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Autophagy is required for endothelial cell alignment and atheroprotection under physiological blood flow
Published in Proceedings of the National Academy of Sciences - PNAS (10-10-2017)“…It has been known for some time that atherosclerotic lesions preferentially develop in areas exposed to lowSS and are characterized by a proinflammatory,…”
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Disulfide HMGB1 derived from platelets coordinates venous thrombosis in mice
Published in Blood (17-11-2016)“…Deep venous thrombosis (DVT) is one of the most common cardiovascular diseases, but its pathophysiology remains incompletely understood. Although sterile…”
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IQB Trends in Student Achievement 2018: A Large-Scale Educational Assessment Study in Germany
Published in Journal of open psychology data (12-12-2022)“…The IQB Trends in Student Achievement 2018 is a nation-wide large-scale educational assessment using a trend design. The study includes achievement tests on…”
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Innovative in vivo rat model for global cerebral hypoxia: a new approach to investigate therapeutic and preventive drugs
Published in Frontiers in physiology (2024)“…Severe acute global cerebral hypoxia can lead to significant disability in humans. Although different animal models have been described to study hypoxia, there…”
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Antibodies and complement are key drivers of thrombosis
Published in Immunity (Cambridge, Mass.) (10-09-2024)“…Venous thromboembolism (VTE) is a common, deadly disease with an increasing incidence despite preventive efforts. Clinical observations have associated…”
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Endothelial autophagic flux hampers atherosclerotic lesion development
Published in Autophagy (02-01-2018)“…Blood flowing in arteries generates shear forces at the surface of the vascular endothelium that control its anti-atherogenic properties. However, due to the…”
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Targeting actin inhibits repair of doxorubicin-induced DNA damage: a novel therapeutic approach for combination therapy
Published in Cell death & disease (03-04-2019)“…Severe side effects often restrict clinical application of the widely used chemotherapeutic drug doxorubicin. In order to decrease required substance…”
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Abstract 590: Autophagy is Required for Endothelial Atheroprotective Signaling Under Physiological Flow
Published in Arteriosclerosis, thrombosis, and vascular biology (01-05-2017)“…Abstract only Objective: Preferential development of atherosclerotic lesions in areas of low shear stress is associated with increased endothelial…”
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In vitro and in vivo characterization of the actin polymerizing compound chondramide as an angiogenic inhibitor
Published in Cardiovascular research (01-11-2014)“…Inhibiting angiogenesis is a major approach in tumour therapy. To combat angiogenesis, the tubulin cytoskeleton has emerged as an interesting target in many…”
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