Search Results - "Busse, Christian"

The promise and challenge of high-throughput sequencing of the antibody repertoire by Georgiou, George, Ippolito, Gregory C, Beausang, John, Busse, Christian E, Wardemann, Hedda, Quake, Stephen R

“…Georgiou and colleagues discuss rapidly evolving methods for high-throughput sequencing of the antibody repertoire, and how the resulting data may be applied…”
Get full text

Sustainability-Related Supply Chain Risks: Conceptualization and Management by Hofmann, Hannes, Busse, Christian, Bode, Christoph, Henke, Michael

“…ABSTRACT There is ample anecdotal evidence suggesting that firms can experience serious losses from social, ecological or ethical problems that exist in their…”
Get full text

Novel Approaches to Analyze Immunoglobulin Repertoires by Wardemann, Hedda, Busse, Christian E

“…Analysis of immunoglobulin (Ig) repertoires aims to comprehend Ig diversity with the goal of predicting humoral immune responses in the context of infection,…”
Get full text

Managing Information Processing Needs in Global Supply Chains: A Prerequisite to Sustainable Supply Chain Management by Busse, Christian, Meinlschmidt, Jan, Foerstl, Kai

“…Sustainability is an important topic in supply chain management research and practice. For buying firms, one of the most pressing challenges associated with…”
Get full text

ALDH4A1 is an atherosclerosis auto-antigen targeted by protective antibodies by Lorenzo, Cristina, Delgado, Pilar, Busse, Christian E., Sanz-Bravo, Alejandro, Martos-Folgado, Inmaculada, Bonzon-Kulichenko, Elena, Ferrarini, Alessia, Gonzalez-Valdes, Ileana B., Mur, Sonia M., Roldán-Montero, Raquel, Martinez-Lopez, Diego, Martin-Ventura, Jose L., Vázquez, Jesús, Wardemann, Hedda, Ramiro, Almudena R.

“…Cardiovascular disease (CVD) is the leading cause of mortality in the world, with most CVD-related deaths resulting from myocardial infarction or stroke. The…”
Get full text

Single‐cell based high‐throughput sequencing of full‐length immunoglobulin heavy and light chain genes by Busse, Christian E., Czogiel, Irina, Braun, Peter, Arndt, Peter F., Wardemann, Hedda

“…Single‐cell PCR and sequencing of full‐length Ig heavy (Igh) and Igk and Igl light chain genes is a powerful tool to measure the diversity of antibody…”
Get full text

Cloning and expression of murine Ig genes from single B cells by Tiller, Thomas, Busse, Christian E., Wardemann, Hedda

“…We have established a highly efficient 96-well format based strategy to characterize the expressed murine antibody repertoire by combining immunoglobulin (Ig)…”
Get full text

Atypical and classical memory B cells produce Plasmodium falciparum neutralizing antibodies by Muellenbeck, Matthias F, Ueberheide, Beatrix, Amulic, Borko, Epp, Alexandra, Fenyo, David, Busse, Christian E, Esen, Meral, Theisen, Michael, Mordmüller, Benjamin, Wardemann, Hedda

“…Antibodies can protect from Plasmodium falciparum (Pf) infection and clinical malaria disease. However, in the absence of constant reexposure, serum…”
Get full text

Adaptive Immune Receptor Repertoire Community recommendations for sharing immune-repertoire sequencing data by Rubelt, Florian, Busse, Christian E, Bukhari, Syed Ahmad Chan, Bürckert, Jean-Philippe, Mariotti-Ferrandiz, Encarnita, Cowell, Lindsay G, Watson, Corey T, Marthandan, Nishanth, Faison, William J, Hershberg, Uri, Laserson, Uri, Corrie, Brian D, Davis, Mark M, Peters, Bjoern, Lefranc, Marie-Paule, Scott, Jamie K, Breden, Felix, Luning Prak, Eline T, Kleinstein, Steven H

“…High-throughput sequencing of B and T cell receptors is routinely being applied in studies of adaptive immunity. The Adaptive Immune Receptor Repertoire (AIRR)…”
Get full text

sciReptor: analysis of single-cell level immunoglobulin repertoires by Imkeller, Katharina, Arndt, Peter F, Wardemann, Hedda, Busse, Christian E

“…The sequencing of immunoglobulin (Ig) transcripts from single B cells yields essential information about Ig heavy:light chain pairing, which is lost in…”
Get full text

OGRDB: a reference database of inferred immune receptor genes by Lees, William, Busse, Christian E, Corcoran, Martin, Ohlin, Mats, Scheepers, Cathrine, Matsen, Frederick A, Yaari, Gur, Watson, Corey T, Collins, Andrew, Shepherd, Adrian J

“…Abstract High-throughput sequencing of the adaptive immune receptor repertoire (AIRR-seq) is providing unprecedented insights into the immune response to…”
Get full text

Direct high‐throughput amplification and sequencing of immunoglobulin genes from single human B cells by Murugan, Rajagopal, Imkeller, Katharina, Busse, Christian E., Wardemann, Hedda

Get full text

IGLV3-21 01 is an inherited risk factor for CLL through the acquisition of a single-point mutation enabling autonomous BCR signaling by Maity, Palash C, Bilal, Mayas, Koning, Marvyn T, Young, Marc, van Bergen, Cornelis A M, Renna, Valerio, Nicolò, Antonella, Datta, Moumita, Gentner-Göbel, Eva, Barendse, Rob S, Somers, Sebastiaan F, de Groen, Ruben A L, Vermaat, Joost S P, Steinbrecher, Daniela, Schneider, Christof, Tausch, Eugen, Bittolo, Tamara, Bomben, Riccardo, Mazzarello, Andrea Nicola, Del Poeta, Giovanni, Kroes, Wilma G M, van Wezel, J Tom, Imkeller, Katharina, Busse, Christian E, Degano, Massimo, Bakchoul, Tamam, Schulz, Axel Ronald, Mei, Henrik, Ghia, Paolo, Kotta, Konstantia, Stamatopoulos, Kostas, Wardemann, Hedda, Zucchetto, Antonella, Chiorazzi, Nicholas, Gattei, Valter, Stilgenbauer, Stephan, Veelken, Hendrik, Jumaa, Hassan

“…The prognosis of chronic lymphocytic leukemia (CLL) depends on different markers, including cytogenetic aberrations, oncogenic mutations, and mutational status…”
Get full text

Maneuvering through Hostile Environments: How Firms Leverage Product and Process Innovativeness by Kach, Andrew, Busse, Christian, Azadegan, Arash, Wagner, Stephan M.

“…ABSTRACT Is focusing on innovativeness the appropriate organizational response in hostile environments? This study addresses four distinct forms of hostile…”
Get full text

Expression Cloning of Antibodies from Single Human B Cells by Rollenske, Tim, Murugan, Rajagopal, Wardemann, Hedda, Busse, Christian E

“…The majority of lymphomas originate from B cells at the germinal center stage. Preferential selection of B-cell clones by a limited set of antigens has been…”
Get more information

IGLV3-2101 is an inherited risk factor for CLL through the acquisition of a single-point mutation enabling autonomous BCR signaling by Maity, Palash C., Bilal, Mayas, Koning, Marvyn T., Young, Marc, van Bergen, Cornelis A. M., Renna, Valerio, Nicolò, Antonella, Datta, Moumita, Gentner-Göbel, Eva, Barendse, Rob S., Somers, Sebastiaan F., de Groen, Ruben A. L., Vermaat, Joost S. P., Steinbrecher, Daniela, Schneider, Christof, Tausch, Eugen, Bittolo, Tamara, Bomben, Riccardo, Mazzarello, Andrea Nicola, del Poeta, Giovanni, Kroes, Wilma G. M., van Wezel, J. Tom, Imkeller, Katharina, Busse, Christian E., Degano, Massimo, Bakchoul, Tamam, Schulz, Axel Ronald, Mei, Henrik, Ghia, Paolo, Kotta, Konstantia, Stamatopoulos, Kostas, Wardemann, Hedda, Zucchetto, Antonella, Chiorazzi, Nicholas, Gattei, Valter, Stilgenbauer, Stephan, Veelken, Hendrik, Jumaa, Hassan

“…The prognosis of chronic lymphocytic leukemia (CLL) depends on different markers, including cytogenetic aberrations, oncogenic mutations, and mutational status…”
Get full text

AIRR Community Standardized Representations for Annotated Immune Repertoires by Vander Heiden, Jason Anthony, Marquez, Susanna, Marthandan, Nishanth, Bukhari, Syed Ahmad Chan, Busse, Christian E, Corrie, Brian, Hershberg, Uri, Kleinstein, Steven H, Matsen Iv, Frederick A, Ralph, Duncan K, Rosenfeld, Aaron M, Schramm, Chaim A, Christley, Scott, Laserson, Uri

“…Increased interest in the immune system's involvement in pathophysiological phenomena coupled with decreased DNA sequencing costs have led to an explosion of…”
Get full text

An efficient single‐cell based method for linking human T cell phenotype to T cell receptor sequence and specificity by Wahl, Ilka, Hoffmann, Sandro, Hundsdorfer, Rebecca, Puchan, Julia, Hoffman, Stephen L., Kremsner, Peter G., Mordmüller, Benjamin, Busse, Christian E., Wardemann, Hedda

“…Single‐cell antigen‐receptor gene amplification and sequencing platforms have been used to characterize T cell receptor (TCR) repertoires but typically fail to…”
Get full text

Clonal selection drives protective memory B cell responses in controlled human malaria infection by Murugan, Rajagopal, Buchauer, Lisa, Triller, Gianna, Kreschel, Cornelia, Costa, Giulia, Pidelaserra Martí, Gemma, Imkeller, Katharina, Busse, Christian E, Chakravarty, Sumana, Sim, B Kim Lee, Hoffman, Stephen L, Levashina, Elena A, Kremsner, Peter G, Mordmüller, Benjamin, Höfer, Thomas, Wardemann, Hedda

“…Affinity maturation, the clonal selection and expansion of antigen-activated B cells expressing somatically mutated antibody variants that develop during T…”
Get more information

A comparison of immunoglobulin IGHV, IGHD and IGHJ genes in wild‐derived and classical inbred mouse strains by Watson, Corey T, Kos, Justin T, Gibson, William S, Newman, Leah, Deikus, Gintaras, Busse, Christian E, Smith, Melissa L, Jackson, Katherine JL, Collins, Andrew M

“…The genomes of classical inbred mouse strains include genes derived from all three major subspecies of the house mouse, Mus musculus. We recently posited that…”
Get full text