Search Results - "Busnena, Belnaser A"
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Olive phenolics as c-Met inhibitors: (-)-Oleocanthal attenuates cell proliferation, invasiveness, and tumor growth in breast cancer models
Published in PloS one (21-05-2014)“…Dysregulation of the Hepatocyte growth factor (HGF)/c-Met signaling axis upregulates diverse tumor cell functions, including cell proliferation, survival,…”
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Novel c-Met inhibitory olive secoiridoid semisynthetic analogs for the control of invasive breast cancer
Published in European journal of medicinal chemistry (08-08-2016)“…Dysregulated receptor tyrosine kinase c-Met and its ligand HGF is valid and attractive molecular target for therapeutic blockade in cancer. Inspired by the…”
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Biphenyls and dibenzofurans of the rosaceous subtribe Malinae and their role as phytoalexins
Published in Planta (01-10-2023)“…Main conclusion Biphenyl and dibenzofuran phytoalexins are differentially distributed among species of the rosaceous subtribe Malinae, which includes apple and…”
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Formation and exudation of biphenyl and dibenzofuran phytoalexins by roots of the apple rootstock M26 grown in apple replant disease soil
Published in Phytochemistry (Oxford) (01-12-2021)“…Apple replant disease (ARD) is a severe soil-borne disease frequently observed in apple tree nurseries and orchards worldwide. One of the responses of apple…”
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Olive-Oil-Derived Oleocanthal Enhances β‑Amyloid Clearance as a Potential Neuroprotective Mechanism against Alzheimer’s Disease: In Vitro and in Vivo Studies
Published in ACS chemical neuroscience (19-06-2013)“…Oleocanthal, a phenolic component of extra-virgin olive oil, has been recently linked to reduced risk of Alzheimer’s disease (AD), a neurodegenerative disease…”
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Olive secoiridoids and semisynthetic bioisostere analogues for the control of metastatic breast cancer
Published in Bioorganic & medicinal chemistry (01-04-2013)“…(−)-Oleocanthal (1) and ligstroside aglycone (2) are common bioactive olive oil secoiridoids. Secoiridoid 1 has been previously reported as a c-MET inhibitor…”
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7
Optimization of Marine Triterpene Sipholenols as Inhibitors of Breast Cancer Migration and Invasion
Published in ChemMedChem (01-03-2013)“…Sipholenol A, a sipholane triterpene isolated from the Red Sea sponge Callyspongia siphonella, has the ability to reverse multidrug resistance in cancer cells…”
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Differential accumulation of phenolics and phytoalexins in seven Malus genotypes cultivated in apple replant disease-affected soil
Published in Scientia horticulturae (15-03-2024)“…•Seven Malus genotypes differe in growth performance in ARD soil.•Formation of phenolics and phytoalexins in roots is differentially induced by ARD.•Early time…”
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Abstract C259: Olive phenolics as c-Met inhibitors: Molecular mechanisms mediating the anticancer effects of oleocanthal in breast cancer cells
Published in Molecular cancer therapeutics (01-11-2013)“…Abstract The Mediterranean countries have lower cancer incidence compared to the rest of European countries and the United States. Olive oil is a key…”
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10
Olive Phenolics as c-Met Inhibitors
Published in PloS one (21-05-2014)“…Dysregulation of the Hepatocyte growth factor (HGF)/c-Met signaling axis upregulates diverse tumor cell functions, including cell proliferation, survival,…”
Get full text
Journal Article