Search Results - "Busija, David W."

Transcriptome analysis reveals sexual disparities in gene expression in rat brain microvessels by Chandra, Partha K, Cikic, Sinisa, Baddoo, Melody C, Rutkai, Ibolya, Guidry, Jessie J, Flemington, Erik K, Katakam, Prasad VG, Busija, David W

“…Sex is an important determinant of brain microvessels (MVs) function and susceptibility to cerebrovascular and neurological diseases, but underlying mechanisms…”
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Sexual differences in mitochondrial and related proteins in rat cerebral microvessels: A proteomic approach by Cikic, Sinisa, Chandra, Partha K, Harman, Jarrod C, Rutkai, Ibolya, Katakam, Prasad VG, Guidry, Jessie J, Gidday, Jeffrey M, Busija, David W

“…Sex differences in mitochondrial numbers and function are present in large cerebral arteries, but it is unclear whether these differences extend to the…”
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Cerebrovascular function and mitochondrial bioenergetics after ischemia-reperfusion in male rats by Rutkai, Ibolya, Merdzo, Ivan, Wunnava, Sanjay V, Curtin, Genevieve T, Katakam, Prasad VG, Busija, David W

“…The underlying factors promoting increased mitochondrial proteins, mtDNA, and dilation to mitochondrial-specific agents in male rats following tMCAO are not…”
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Distinct fate, dynamics and niches of renal macrophages of bone marrow or embryonic origins by Liu, Fengming, Dai, Shen, Feng, Dechun, Qin, Zhongnan, Peng, Xiao, Sakamuri, Siva S. V. P., Ren, Mi, Huang, Li, Cheng, Min, Mohammad, Kabir E., Qu, Ping, Chen, Yong, Zhao, Chunling, Zhu, Faliang, Liang, Shujian, Aktas, Bertal H., Yang, Xiaofeng, Wang, Hong, Katakam, Prasad V. G., Busija, David W., Fischer, Tracy, Datta, Prasun K., Rappaport, Jay, Gao, Bin, Qin, Xuebin

“…Renal macrophages (RMs) participate in tissue homeostasis, inflammation and repair. RMs consist of embryo-derived (EMRMs) and bone marrow-derived RMs (BMRMs),…”
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Mitochondrial dynamics associated with oxygen-glucose deprivation in rat primary neuronal cultures by Wappler, Edina A, Institoris, Adam, Dutta, Somhrita, Katakam, Prasad V G, Busija, David W

“…Our objective was to investigate the mitochondrial dynamics following oxygen-glucose deprivation (OGD) in cultured rat cortical neurons. We documented changes…”
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The mechanistic target of rapamycin (mTOR) pathway and S6 Kinase mediate diazoxide preconditioning in primary rat cortical neurons by Dutta, Somhrita, Rutkai, Ibolya, Katakam, Prasad V. G., Busija, David W.

“…We examined the role of the mechanistic target of rapamycin (mTOR) pathway in delayed diazoxide (DZ)‐induced preconditioning of cultured rat primary cortical…”
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Protection against recurrent stroke with resveratrol: endothelial protection by Clark, Darren, Tuor, Ursula I, Thompson, Roger, Institoris, Adam, Kulynych, Angela, Zhang, Xu, Kinniburgh, David W, Bari, Ferenc, Busija, David W, Barber, Philip A

“…Despite increased risk of a recurrent stroke following a minor stroke, information is minimal regarding the interaction between injurious mild cerebral…”
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Mitochondrial-mediated suppression of ROS production upon exposure of neurons to lethal stress: Mitochondrial targeted preconditioning by Busija, David W., Gaspar, Tamas, Domoki, Ferenc, Katakam, Prasad V., Bari, Ferenc

“…Preconditioning represents the condition where transient exposure of cells to an initiating event leads to protection against subsequent, potentially lethal…”
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Untargeted Metabolomic Profiling of Extracellular Vesicles Isolated from Human Seminal Plasma by Panner Selvam, Manesh Kumar, Chandra, Partha K, Bakhtiary, Zahra, Busija, David W, Sikka, Suresh C

“…Seminal extracellular vesicles (SemEVs) are repositories of biomolecules, including metabolites involved in the regulation of sperm function. The correlation…”
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Acetaminophen and the cyclooxygenase-3 puzzle: sorting out facts, fictions, and uncertainties by Kis, Bela, Snipes, James A, Busija, David W

“…Cyclooxygenase (COX)-3, a novel COX splice variant, was suggested as the key to unlocking the mystery of the mechanism of action of acetaminophen. Although…”
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Depolarization of mitochondria in neurons promotes activation of nitric oxide synthase and generation of nitric oxide by Katakam, Prasad V G, Dutta, Somhrita, Sure, Venkata N, Grovenburg, Samuel M, Gordon, Angellica O, Peterson, Nicholas R, Rutkai, Ibolya, Busija, David W

“…The diverse signaling events following mitochondrial depolarization in neurons are not clear. We examined for the first time the effects of mitochondrial…”
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Circulating Plasma Exosomal Proteins of Either SHIV-Infected Rhesus Macaque or HIV-Infected Patient Indicates a Link to Neuropathogenesis by Chandra, Partha K, Braun, Stephen E, Maity, Sudipa, Castorena-Gonzalez, Jorge A, Kim, Hogyoung, Shaffer, Jeffrey G, Cikic, Sinisa, Rutkai, Ibolya, Fan, Jia, Guidry, Jessie J, Worthylake, David K, Li, Chenzhong, Abdel-Mageed, Asim B, Busija, David W

“…Despite the suppression of human immunodeficiency virus (HIV) replication by combined antiretroviral therapy (cART), 50-60% of HIV-infected patients suffer…”
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Insulin-Induced Generation of Reactive Oxygen Species and Uncoupling of Nitric Oxide Synthase Underlie the Cerebrovascular Insulin Resistance in Obese Rats by Katakam, Prasad VG, Snipes, James A, Steed, Mesia M, Busija, David W

“…Hyperinsulinemia accompanying insulin resistance (IR) is an independent risk factor for stroke. The objective is to examine the cerebrovascular actions of…”
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Delayed neuronal preconditioning by NS1619 is independent of calcium activated potassium channels by Gáspár, Tamás, Katakam, Prasad, Snipes, James A, Kis, Béla, Domoki, Ferenc, Bari, Ferenc, Busija, David W

“…1,3-Dihydro-1-[2-hydroxy-5-(trifluoromethyl)phenyl]-5-(trifluoromethyl)-2H-benzimidazol-2-one (NS1619), a potent activator of the large conductance Ca²⁺…”
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Rosuvastatin improves cerebrovascular function in Zucker obese rats by inhibiting NAD(P)H oxidase-dependent superoxide production by Erdös, Benedek, Snipes, James A, Tulbert, Christina D, Katakam, Prasad, Miller, Allison W, Busija, David W

“…Insulin-resistance induces cerebrovascular dysfunction and increases the risk for stroke. We investigated whether rosuvastatin (RSV), a…”
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Cerebrovascular Dysfunction in Zucker Obese Rats Is Mediated by Oxidative Stress and Protein Kinase C by Erdös, Benedek, Snipes, James A, Miller, Allison W, Busija, David W

“…Cerebrovascular Dysfunction in Zucker Obese Rats Is Mediated by Oxidative Stress and Protein Kinase C Benedek Erdös 1 2 , James A. Snipes 1 , Allison W. Miller…”
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Diazoxide induces delayed pre‐conditioning in cultured rat cortical neurons by Kis, Bela, Rajapakse, Nishadi C., Snipes, James A., Nagy, Krisztina, Horiguchi, Takashi, Busija, David W.

“…We investigated the effect of diazoxide on neuronal survival in primary cultures of rat cortical neurons against oxygen–glucose deprivation (OGD). Diazoxide…”
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Contribution of poly(ADP-ribose) polymerase to postischemic blood-brain barrier damage in rats by Lenzsér, Gábor, Kis, Béla, Snipes, James A, Gáspár, Tamás, Sándor, Péter, Komjáti, Katalin, Szabó, Csaba, Busija, David W

“…The nuclear enzyme poly(ADP-ribose) polymerase (PARP) is activated by oxidative stress and plays a significant role in postischemic brain injury. We assessed…”
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Impaired insulin-induced vasodilation in small coronary arteries of Zucker obese rats is mediated by reactive oxygen species by Katakam, Prasad V G, Tulbert, Christina D, Snipes, James A, Erdös, Benedek, Miller, Allison W, Busija, David W

“…Insulin resistance (IR) and associated hyperinsulinemia are major risk factors for coronary artery disease. Mechanisms linking hyperinsulinemia to coronary…”
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Cerebromicrovascular endothelial cells are resistant to L-glutamate by Domoki, Ferenc, Kis, Béla, Gáspár, Tamás, Bari, Ferenc, Busija, David W

“…Cerebral microvascular endothelial cells (CMVECs) have recently been implicated as targets of excitotoxic injury by l-glutamate (l-glut) or…”
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