Search Results - "Busignies, V."

Comparative study between Drucker-Prager/Cap and modified Cam-Clay models for the numerical simulation of die compaction of pharmaceutical powders by Diarra, H., Mazel, V., Busignies, V., Tchoreloff, P.

“…Numerical simulation with finite element method is commonly used to model the process of die compaction. In pharmaceutical field, the Drucker-Prager/Cap (DPC)…”
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Lamination of pharmaceutical tablets due to air entrapment: Direct visualization and influence of the compact thickness by Mazel, V., Busignies, V., Diarra, H., Tchoreloff, P.

“…[Display omitted] Capping and lamination are two problems that are often faced during the industrial manufacturing of pharmaceutical tablets. Several reasons…”
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Sensitivity of elastic parameters during the numerical simulation of pharmaceutical die compaction process with Drucker-Prager/Cap model by Diarra, H., Mazel, V., Busignies, V., Tchoreloff, P.

“…Numerical simulation of the die compaction process with Drucker-Prager/Cap (DPC) model is increasingly used to understand the powder behavior during…”
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Shear strength of pharmaceutical tablets: Theoretical considerations, evaluation and relation with the capping tendency of biconvex tablets by Mazel, V., Diarra, H., Busignies, V., Tchoreloff, P.

“…[Display omitted] Capping is a major industrial issue during pharmaceutical powder compression, especially in the case of biconvex tablets. Several articles…”
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Finite Element Method (FEM) modeling of the powder compaction of cosmetic products: Comparison between simulated and experimental results by Diarra, H., Mazel, V., Boillon, A., Rehault, L., Busignies, V., Bureau, S., Tchoreloff, P.

“…The numerical modeling of the die compaction process using the Finite Element Method (FEM) and the Drucker Prager Cap (DPC) Model has been widely developed in…”
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Reevaluation of the diametral compression test for tablets using the flattened disc geometry by Mazel, V., Guerard, S., Croquelois, B., Kopp, J.B., Girardot, J., Diarra, H., Busignies, V., Tchoreloff, P.

“…[Display omitted] Mechanical strength is an important critical quality attribute for tablets. It is classically measured, in the pharmaceutical field, using…”
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Prediction of the compressibility of complex mixtures of pharmaceutical powders by Busignies, V., Mazel, V., Diarra, H., Tchoreloff, P.

“…The model we proposed was able to predict with a good precision the final density of the compacts of three different complex mixtures at different compaction…”
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Development and pre-clinical evaluation in the swine model of a mucosal vaccine tablet for human influenza viruses: A proof-of-concept study by Busignies, V., Simon, G., Mollereau, G., Bourry, O., Mazel, V., Rosa-Calatrava, M., Tchoreloff, P.

“…[Display omitted] Liquid vaccine formulations present some disadvantages such as stability problems, cold chain requirement or administration by trained…”
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Evaluation of a rotary tablet press simulator as a tool for the characterization of compaction properties of pharmaceutical products by Michaut, F, Busignies, V, Fouquereau, C, de Barochez, B Huet, Leclerc, B, Tchoreloff, P

“…The Stylcam 100R, a rotary press simulator, was designed to simulate speed profiles of rotary tablet presses. Such a simulator was qualified by numerous…”
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The surface layer of pharmaceutical compacts: The role of the punch surface and its impact on the mechanical properties of the compacts by Mazel, V., Busignies, V., Diarra, H., Reiche, I., Tchoreloff, P.

“…During pharmaceutical compaction, the interaction between the punch and the powder determines the formation and the aspect of the surface of the compact. In…”
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Quantitative measurements of localized density variations in cylindrical tablets using X-ray microtomography by Busignies, Virginie, Leclerc, Bernard, Porion, Patrice, Evesque, Pierre, Couarraze, Guy, Tchoreloff, Pierre

“…Direct compaction is a complex process that results in a density distribution inside the tablets which is often heterogeneous. Therefore, the density…”
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Curing of aqueous polymeric film coatings: Importance of the coating level and type of plasticizer by Yang, Q.W., Flament, M.P., Siepmann, F., Busignies, V., Leclerc, B., Herry, C., Tchoreloff, P., Siepmann, J.

“…The aim of this study was to better understand the effects of the curing conditions on the resulting drug release patterns from pellets coated with aqueous…”
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Compaction behaviour and new predictive approach to the compressibility of binary mixtures of pharmaceutical excipients by Busignies, V., Leclerc, B., Porion, P., Evesque, P., Couarraze, G., Tchoreloff, P.

“…The compressibility of three pharmaceutical excipients (microcrystalline cellulose, lactose and anhydrous calcium phosphate) and their binary mixtures was…”
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Compaction of crystallographic forms of pharmaceutical granular lactoses. I. Compressibility by Busignies, V., Tchoreloff, P., Leclerc, B., Besnard, M., Couarraze, G.

“…Physico-chemical properties of a substance including the compaction behaviour are directly connected with the crystalline structure. The aim of this work is to…”
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Investigation and modelling approach of the mechanical properties of compacts made with binary mixtures of pharmaceutical excipients by Busignies, V., Leclerc, B., Porion, P., Evesque, P., Couarraze, G., Tchoreloff, P.

“…Three pharmaceutical excipients (microcrystalline cellulose, lactose, anhydrous calcium phosphate) and their binary mixtures were compacted to form compacts of…”
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Anisotropic Porous Structure of Pharmaceutical Compacts Evaluated by PGSTE-NMR in Relation to Mechanical Property Anisotropy by Porion, Patrice, Busignies, Virginie, Mazel, Vincent, Leclerc, Bernard, Evesque, Pierre, Tchoreloff, Pierre

“…Purpose The pore space anisotropy of pharmaceutical compacts was evaluated in relation to the mechanical property anisotropy. Methods The topology and the pore…”
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Application of PGSTE-NMR technique to characterize the porous structure of pharmaceutical tablets by Busignies, Virginie, Porion, Patrice, Leclerc, Bernard, Evesque, Pierre, Tchoreloff, Pierre

“…Direct compaction of pharmaceutical tablets is a complex process that results in a heterogeneous density distribution inside the compact. In the present study,…”
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New application of PGSE-NMR technique to characterize the porous structure of pharmaceutical tablets by Busignies, V., Poirion, P., Leclerc, B., Evesque, P., Tchoreloff, P.

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