Search Results - "Bushra Ijaz"
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1
Oxidative toxicity in diabetes and Alzheimer's disease: mechanisms behind ROS/ RNS generation
Published in Journal of biomedical science (19-09-2017)“…Reactive oxidative species (ROS) toxicity remains an undisputed cause and link between Alzheimer's disease (AD) and Type-2 Diabetes Mellitus (T2DM). Patients…”
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2
The Insight of In Silico and In Vitro evaluation of Beta vulgaris phytochemicals against Alzheimer's disease targeting acetylcholinesterase
Published in PloS one (03-03-2022)“…B. vulgaris extracts possess antioxidant, anti-inflammatory along with its role in improving memory disorders. Subsequently, in vitro and in silico studies of…”
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3
Perception of breast cancer risk factors: Dysregulation of TGF-β/miRNA axis in Pakistani females
Published in PloS one (23-07-2021)“…Breast cancer poses a serious health risk for women throughout the world. Among the Asian population, Pakistani women have the highest risk of developing…”
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4
Salt tolerance in indica rice cell cultures depends on a fine tuning of ROS signalling and homeostasis
Published in PloS one (30-04-2019)“…Among cereal crops, salinity tolerance is rare and complex. Multiple genes control numerous pathways, which constitute plant's response to salinity. Cell…”
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5
Circulating tumor DNA in blood: Future genomic biomarkers for cancer detection
Published in Experimental hematology (01-09-2018)“…•Tumor heterogeneity causes significant challenges in designing cancer therapies.•Cell free circulating tumor DNA (ctDNA) can monitor tumor burden, therapy…”
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Glycosylation of Recombinant Anticancer Therapeutics in Different Expression Systems with Emerging Technologies
Published in Cancer research (Chicago, Ill.) (01-06-2018)“…Glycosylation, a posttranslational modification, has a major role in recombinant anticancer therapeutic proteins, as most of the approved recombinant…”
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Chitosan-Linseed mucilage polyelectrolyte complex nanoparticles of Methotrexate: In vitro cytotoxic efficacy and toxicological studies
Published in Arabian journal of chemistry (01-02-2023)“…The goal of this research was to develop, fabricate and analyze polymeric nanoparticles for the administration of methotrexate (MTX). Linseed mucilage and…”
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pH Responsive Abelmoschus esculentus Mucilage and Administration of Methotrexate: In-Vitro Antitumor and In-Vivo Toxicity Evaluation
Published in International journal of molecular sciences (01-03-2022)“…The rapid progression in biomaterial nanotechnology apprehends the potential of non-toxic and potent polysaccharide delivery modules to overcome oral…”
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Eco-smart biocontrol strategies utilizing potent microbes for sustainable management of phytopathogenic diseases
Published in Biotechnology reports (Amsterdam, Netherlands) (01-12-2024)“…•Biocontrol strategies offer eco-friendly solutions to combat phytopathogenic diseases, reducing reliance on harmful chemical treatments.•Effective management…”
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10
Formulation and evaluation of quince seeds mucilage – sodium alginate microspheres for sustained delivery of cefixime and its toxicological studies
Published in Arabian journal of chemistry (01-06-2022)“…[Display omitted] Quince seed mucilage was used in a combination of sodium alginate to develop sustained-release microspheres of cefixime. Physical…”
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11
Association of depression with dental caries and periodontal disease at a tertiary care hospital
Published in Journal of the Pakistan Medical Association (01-05-2021)“…To determine the association of depression with dental caries and periodontal disease. The cross-sectional descriptive study was conducted at the Nishtar…”
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12
Phytochemical Screening and Protective Effects of Prunus persica Seeds Extract on Carbon Tetrachloride-Induced Hepatic Injury in Rats
Published in Current pharmaceutical biotechnology (2022)“…Carbon tetrachloride (CCl4) is a dynamic environmental toxin released from chemical factories and its concentration in the atmosphere is accelerating at an…”
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Evaluation of betanin-encapsulated biopolymeric nanoparticles for antitumor activity via PI3K/Akt/mTOR signaling pathway
Published in Arabian journal of chemistry (01-12-2023)“…Cancer nanotheranostic components are useful in monitoring drug delivery and potency against tumor cells. Current chemotherapeutic agents exhibit severe side…”
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14
H2O2 Signature and Innate Antioxidative Profile Make the Difference Between Sensitivity and Tolerance to Salt in Rice Cells
Published in Frontiers in plant science (23-10-2018)“…Salt tolerance is a complex trait that varies between and within species. H 2 O 2 profiles as well as antioxidative systems have been investigated in the…”
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Ficus benghalensis as Potential Inhibitor of 5 α -Reductase for Hair Growth Promotion: In Vitro , In Silico , and In Vivo Evaluation
Published in Frontiers in pharmacology (07-12-2021)“…The screening of hair follicles, dermal papilla cells, and keratinocytes through , , and histology has previously been reported to combat alopecia. has been…”
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Prevalence of BRCA1 and BRCA2 germline variants in an unselected pancreatic cancer patient cohort in Pakistan
Published in Hereditary cancer in clinical practice (11-11-2023)“…Background BRCA1 and BRCA2 (BRCA1/2) are the most frequently investigated genes among Caucasian pancreatic cancer patients, whereas limited reports are…”
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Phytochemical analysis of Berberis lyceum methanolic extract and its antiviral activity through the restoration of MAPK signaling pathway modulated by HCV NS5A
Published in Asian Pacific journal of tropical biomedicine (01-03-2021)“…Objective: To evaluate the antiviral activity and phytochemicals of selected plant extracts and their effect on the mitogen-activated protein kinase (MAPK)…”
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HCV infection causes cirrhosis in human by step-wise regulation of host genes involved in cellular functioning and defense during fibrosis: Identification of bio-markers
Published in Genes & diseases (01-09-2019)“…Chronic Hepatitis C Viral (HCV) infection is a leading health problem worldwide and resulted in fibrotic scar formation, and finally liver-cirrhosis. Although…”
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A comparison of four fibrosis indexes in chronic HCV: development of new fibrosis-cirrhosis index (FCI)
Published in BMC gastroenterology (21-04-2011)“…Hepatitis C can lead to liver fibrosis and cirrhosis. We compared readily available non-invasive fibrosis indexes for the fibrosis progression discrimination…”
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In vivo effects of Rauvolfia vomitoria (Apocynaceae) ethanolic extract on sexual performance and reproductive activity in male rats
Published in Andrologia (01-02-2020)“…Plants and plant‐derived products have a long history in the treatment of sexual disorders. Rauvolfia vomitoria is one of such plant used traditionally for the…”
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