Search Results - "Bushmann, Frederic D"

Improving the Assessment of Risk Factors Relevant to Potential Carcinogenicity of Gene Therapies: A Consensus Article by Klapwijk, Jan C, Del Rio Espinola, Alberto, Libertini, Silvana, Collin, Philippe, Fellows, Mick D, Jobling, Susan, Lynch, Anthony M, Martus, HansJoerg, Vickers, Catherine, Zeller, Andreas, Biasco, Luca, Brugman, Martijn H, Bushmann, Frederic D, Cathomen, Toni, Ertl, Hildegrund C J, Gabriel, Richard, Gao, Guangping, Jadlowsky, Julie K, Kimber, Ian, Lanz, Thomas A, Levine, Bruce L, Micklethwaite, Kenneth P, Onodera, Masafumi, Pizzurro, Daniella M, Reed, Simon, Rothe, Michael, Sabatino, Denise E, Salk, Jesse J, Schambach, Axel, Themis, Michael, Yuan, Jing

“…Regulators and industry are actively seeking improvements and alternatives to current models and approaches to evaluate potential carcinogenicity of gene…”
Get more information

Loss of p19Arf in a Rag1−/− B-cell precursor population initiates acute B-lymphoblastic leukemia by Hauer, Julia, Mullighan, Charles, Morillon, Estelle, Wang, Gary, Bruneau, Julie, Brousse, Nicole, Lelorc'h, Marc, Romana, Serge, Boudil, Amine, Tiedau, Daniela, Kracker, Sven, Bushmann, Frederic D., Borkhardt, Arndt, Fischer, Alain, Hacein-Bey-Abina, Salima, Cavazzana-Calvo, Marina

“…In human B-acute lymphoblastic leukemia (B-ALL), RAG1-induced genomic alterations are important for disease progression. However, given that biallelic loss of…”
Get full text

Leukemia Prone B-Precursor Population in a p19ARF-/-RAG1-/- Mouse Model by Hauer, Julia, Mullighan, Charles G., Morillon, Estelle, Wang, Gary P, Bruneau, Julie, Brousse, Nicole, Borkhardt, Arndt, Bushmann, Frederic D, Fischer, Alain, Hacein-Bey-Abina, Salima, Cavazzana-Calvo, Marina

“…Abstract 3971 Poster Board III-907 Aberrant V(D)J-recombination may contribute to the oncogenic transformation of B-lymphoid precursor cells, suggesting that…”
Get full text