Search Results - "Bushman, W."

The Sonic Hedgehog pathway stimulates prostate tumor growth by paracrine signaling and recapitulates embryonic gene expression in tumor myofibroblasts by Shaw, A, Gipp, J, Bushman, W

“…The Hedgehog (Hh) pathway contributes to prostate cancer growth and progression. The presence of robust Sonic Hedgehog (Shh) expression in both normal prostate…”
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Mapping the Degradable Kinome Provides a Resource for Expedited Degrader Development by Donovan, Katherine A., Ferguson, Fleur M., Bushman, Jonathan W., Eleuteri, Nicholas A., Bhunia, Debabrata, Ryu, SeongShick, Tan, Li, Shi, Kun, Yue, Hong, Liu, Xiaoxi, Dobrovolsky, Dennis, Jiang, Baishan, Wang, Jinhua, Hao, Mingfeng, You, Inchul, Teng, Mingxing, Liang, Yanke, Hatcher, John, Li, Zhengnian, Manz, Theresa D., Groendyke, Brian, Hu, Wanyi, Nam, Yunju, Sengupta, Sandip, Cho, Hanna, Shin, Injae, Agius, Michael P., Ghobrial, Irene M., Ma, Michelle W., Che, Jianwei, Buhrlage, Sara J., Sim, Taebo, Gray, Nathanael S., Fischer, Eric S.

“…Targeted protein degradation (TPD) refers to the use of small molecules to induce ubiquitin-dependent degradation of proteins. TPD is of interest in drug…”
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Proteomics-Based Identification of DUB Substrates Using Selective Inhibitors by Bushman, Jonathan W, Donovan, Katherine A, Schauer, Nathan J, Liu, Xiaoxi, Hu, Wanyi, Varca, Anthony C, Buhrlage, Sara J, Fischer, Eric S

“…Deubiquitinating enzymes (DUBs) catalyze the removal of ubiquitin, thereby reversing the activity of E3 ubiquitin ligases and are central to the control of…”
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Selective degradation-inducing probes for studying cereblon (CRBN) biology by Powell, Chelsea E, Du, Guangyan, Bushman, Jonathan W, He, Zhixiang, Zhang, Tinghu, Fischer, Eric S, Gray, Nathanael S

“…Targeted protein degradation represents a rapidly growing area in drug discovery and development. Moreover, small molecules that induce the targeted…”
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Growth, morphogenesis, and differentiation during mouse prostate development in situ, in renal grafts, and in vitro by Doles, J.D., Vezina, C.M., Lipinski, R.J., Peterson, R.E., Bushman, W.

“…BACKGROUND In vitro organ culture and renal grafting of the urogenital sinus (UGS) have both been used as models of prostate development. However, neither has…”
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P75 by Weber, J.J, Jerde, T.J, Huang, W, Bushman, W

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Anti-adipogenic effects of interferon-gamma is mediated by a stat5-smad3 dyad in visceral adipose mesenchymal stromal cells by Das, R., Giri, J., Paul, P., Froelich, N., Chinnadurai, R., Bushman, W., Galipeau, J.

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Protein gel electrophoresis in the undergraduate physics laboratory by Miles, Danny G., Bushman, David W., Chen, Zhong-Ying

“…We describe an undergraduate laboratory experiment in protein gel electrophoresis that uses readily available apparatus and materials. The separation of a…”
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019 Assessing the Variability in Insurance Coverage Transparency for Male Sexual Health Conditions in the United States by Le, B., Paolone, D., McAchran, S., Gralneck, D., Bushman, W.

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Overexpression of c-src Enhances β-Adrenergic-Induced cAMP Accumulation by Bushman, Wade A., Wilson, Linda K., Luttrell, Deirdre K., Moyers, Julie S., Parsons, Sarah J.

“…During our investigations into the physiological role of c-src tyrosine kinase in normal cells, we found that clonal transfectants of C3H10T1/2 murine…”
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Evaluation and treatment of urinary incontinence in the adult by Bushman, W

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Autonomous DNA binding domains of lambda integrase recognize two different sequence families by Moitoso de Vargas, L, Pargellis, C A, Hasan, N M, Bushman, E W, Landy, A

“…The 40 kd lambda Integrase protein is shown to contain two autonomous DNA binding domains with different sequence specificities. Competition experiments in…”
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Definitive Identification of a Member of the Epstein--Barr Virus Nuclear Protein 3 Family by Hennessy, Kevin, Wang, Fred, Bushman, Ellen Woodland, Kieff, Elliott

“…Some Epstein--Barr virus (EBV) immune human antisera are known to react with a 142-kDa protein, EBV-encoded nuclear antigen 3 (EBNA3), which, like EBNA1 and…”
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Interaction of the λ Site-Specific Recombination Protein Xis with Attachment Site DNA by Yin, Samuel, Bushman, Wade, Landy, Arthur

“…Nuclease protection experiments show that Xis protein of bacteriophage λ specifically binds attachment (att) site DNA. The region of Xis binding, present in…”
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Immunohistochemical staining of ras p21: staining in benign and malignant prostate tissue by Bushman, E C, Nayak, R N, Bushman, W

“…A total of 124 specimens of prostate tissue (25 normal prostate, 41 benign prostatic hyperplasia, 58 adenocarcinoma) was immunostained for ras p21 using a…”
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Long-term results of the Stamey bladder neck suspension: direct comparison with the Marshall-Marchetti-Krantz procedure by Clemens, J Q, Stern, J A, Bushman, W A, Schaeffer, A J

“…We performed followup of a cohort of women who underwent the Stamey endoscopic needle suspension (group 1) or the Marshall-Marchetti-Krantz vesicourethropexy…”
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Hedgehog Signaling Promotes Prostate Xenograft Tumor Growth by Fan, Lian, Pepicelli, Carmen V, Dibble, Christian C, Catbagan, Winnie, Zarycki, Jodi L, Laciak, Robert, Gipp, Jerry, Shaw, Aubie, Lamm, Marilyn L. G, Munoz, Alejandro, Lipinski, Robert, Thrasher, J. Brantley, Bushman, Wade

“…During fetal prostate development, Sonic hedgehog (Shh) expression by the urogenital sinus epithelium activates Gli-1 expression in the adjacent mesenchyme and…”
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The use of urea for dissolution of urinary mucus in urinary tract reconstruction by Bushman, W, Howards, S S

“…Increased urinary mucus is common after urinary tract reconstruction involving the use of bowel segments. This mucus can prove troublesome when it interferes…”
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The Role of Carbohydrate Metabolism in the Regulation of Postfeeding Diuresis in Adult Helicoverpa zea (Lepidoptera: Noctuidae) by Bushman, David W, McGinley, Sarah M. G, Einsmann, Juliet E, Robel, David K

“…The effects of hemolymph sugar levels and carbohydrate metabolism on postfeeding diuresis in corn earworm moths, Helicoverpa zea (Boddie) were examined. High…”
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Effects of age and meal composition on feeding behavior and postfeeding diuresis in adult Helicoverpa zea (Lepidoptera: Noctuidae) by Bushman, D.W. (Mount Saint Mary's College, Emmitsburg, MD.)

“…The effects of age and meal composition on feeding behavior and postfeeding diuresis in corn earworm moths have been investigated. Meal size is governed by the…”
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