Search Results - "Bush, Matthew"

The actinobacterial WhiB‐like (Wbl) family of transcription factors by Bush, Matthew J.

“…Summary The WhiB‐like (Wbl) family of proteins are exclusively found in Actinobacteria. Wbls have been shown to play key roles in virulence and antibiotic…”
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FBXL5 Regulates IRP2 Stability in Iron Homeostasis via an Oxygen-Responsive [2Fe2S] Cluster by Wang, Hui, Shi, Hui, Rajan, Malini, Canarie, Elizabeth R., Hong, Seoyeon, Simoneschi, Daniele, Pagano, Michele, Bush, Matthew F., Stoll, Stefan, Leibold, Elizabeth A., Zheng, Ning

“…Cellular iron homeostasis is dominated by FBXL5-mediated degradation of iron regulatory protein 2 (IRP2), which is dependent on both iron and oxygen. However,…”
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Large-Scale Structural Characterization of Drug and Drug-Like Compounds by High-Throughput Ion Mobility-Mass Spectrometry by Hines, Kelly M, Ross, Dylan H, Davidson, Kimberly L, Bush, Matthew F, Xu, Libin

“…Ion mobility-mass spectrometry (IM-MS) can provide orthogonal information, i.e., m/z and collision cross section (CCS), for the identification of drugs and…”
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Ion mobility mass spectrometry of peptide, protein, and protein complex ions using a radio-frequency confining drift cell by Allen, Samuel J, Giles, Kevin, Gilbert, Tony, Bush, Matthew F

“…Ion mobility mass spectrometry experiments enable the characterization of mass, assembly, and shape of biological molecules and assemblies. Here, a new…”
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c-di-GMP signalling and the regulation of developmental transitions in streptomycetes by Bush, Matthew J., Tschowri, Natalia, Schlimpert, Susan, Flärdh, Klas, Buttner, Mark J.

“…Key Points The erection of reproductive aerial hyphae and sporulation septation are the two most striking developmental transitions in the life cycle of…”
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Collision Cross Sections of Proteins and Their Complexes: A Calibration Framework and Database for Gas-Phase Structural Biology by Bush, Matthew F, Hall, Zoe, Giles, Kevin, Hoyes, John, Robinson, Carol V, Ruotolo, Brandon T

“…Collision cross sections in both helium and nitrogen gases were measured directly using a drift cell with RF ion confinement inserted within a quadrupole/ion…”
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Quantitatively Differentiating Antibodies Using Charge-State Manipulation, Collisional Activation, and Ion Mobility-Mass Spectrometry by Gozzo, Theresa A., Bush, Matthew F.

“…Antibody-based therapeutics continue to expand both in the number of products and in their use in patients. These heterogeneous proteins challenge traditional…”
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Effects of charge on protein ion structure: Lessons from cation‐to‐anion, proton‐transfer reactions by Gozzo, Theresa A., Bush, Matthew F.

“…Collision cross‐section values, which can be determined using ion mobility experiments, are sensitive to the structures of protein ions and useful for…”
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Clinical Practice Guideline: Ménière’s Disease by Basura, Gregory J., Adams, Meredith E., Monfared, Ashkan, Schwartz, Seth R., Antonelli, Patrick J., Burkard, Robert, Bush, Matthew L., Bykowski, Julie, Colandrea, Maria, Derebery, Jennifer, Kelly, Elizabeth A., Kerber, Kevin A., Koopman, Charles F., Kuch, Amy Angie, Marcolini, Evie, McKinnon, Brian J., Ruckenstein, Michael J., Valenzuela, Carla V., Vosooney, Alexis, Walsh, Sandra A., Nnacheta, Lorraine C., Dhepyasuwan, Nui, Buchanan, Erin M.

“…Objective Ménière’s disease (MD) is a clinical condition defined by spontaneous vertigo attacks (each lasting 20 minutes to 12 hours) with documented low- to…”
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Collision-Induced Unfolding Is Sensitive to the Polarity of Proteins and Protein Complexes by Hong, Seoyeon, Bush, Matthew F.

“…Collision-induced unfolding (CIU) uses ion mobility to probe the structures of ions of proteins and noncovalent complexes as a function of the extent of…”
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Charge-State Dependent Compaction and Dissociation of Protein Complexes: Insights from Ion Mobility and Molecular Dynamics by Hall, Zoe, Politis, Argyris, Bush, Matthew F, Smith, Lorna J, Robinson, Carol V

“…Collapse to compact states in the gas phase, with smaller collision cross sections than calculated for their native-like structure, has been reported…”
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Structural Characterization of Drug-like Compounds by Ion Mobility Mass Spectrometry: Comparison of Theoretical and Experimentally Derived Nitrogen Collision Cross Sections by Campuzano, Iain, Bush, Matthew F, Robinson, Carol V, Beaumont, Claire, Richardson, Keith, Kim, Hyungjun, Kim, Hugh I

“…We present the use of drug-like molecules as a traveling wave (T-wave) ion mobility (IM) calibration sample set, covering the m/z range of 122.1–609.3, the…”
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Ion Mobility Mass Spectrometry of Peptide Ions: Effects of Drift Gas and Calibration Strategies by Bush, Matthew F, Campuzano, Iain D. G, Robinson, Carol V

“…One difficulty in using ion mobility (IM) mass spectrometry (MS) to improve the specificity of peptide ion assignments is that IM separations are performed…”
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Structural Dynamics of Native-Like Ions in the Gas Phase: Results from Tandem Ion Mobility of Cytochrome c by Allen, Samuel J, Eaton, Rachel M, Bush, Matthew F

“…Ion mobility (IM) is a gas-phase separation technique that is used to determine the collision cross sections of native-like ions of proteins and protein…”
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Evaluating Equity Through the Social Determinants of Hearing Health by Schuh, Marissa R., Bush, Matthew L.

“…Hearing loss in adults is a significant public health problem throughout the world. Undiagnosed and untreated hearing loss causes a measurable impact on health…”
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Barriers to Rehabilitation Care in Pediatric Cochlear Implant Recipients by Noblitt, Bryce, Alfonso, Kristan P, Adkins, Margaret, Bush, Matthew L

“…OBJECTIVE:The purpose of this study was to assess barriers to rehabilitation care for pediatric cochlear implant (CI) recipients. STUDY DESIGN:Cross-sectional…”
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Comparison of Adult and Pediatric Cochlear Implant Wound Complications: A Meta‐Analysis by Ekman, Brady, Laureano, Jack, Balasuriya, Beverly, Mahairas, Anthony, Bush, Matthew L.

“…Objective To compare age‐related differences in wound complications following cochlear implantation (CI). Methods We performed a systematic review of PubMed,…”
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Towards IMn with electrostatic drift fields: Resetting the potential of trapped ions between dimensions of ion mobility by Zercher, Benjamin P., Feng, Yuan, Bush, Matthew F.

“…Increasing the dimensionality of ion mobility (IM) presents an enticing opportunity to increase the information content and selectivity of many analyses…”
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Folding of Protein Ions in the Gas Phase after Cation-to-Anion Proton-Transfer Reactions by Laszlo, Kenneth J, Munger, Eleanor B, Bush, Matthew F

“…The structure and folding of a protein in solution depends on noncovalent interactions within the protein and those with surrounding ions and molecules…”
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A Flexible, Modular Platform for Multidimensional Ion Mobility of Native-like Ions by Eaton, Rachel M., Zercher, Benjamin P., Wageman, AnneClaire, Bush, Matthew F.

“…Native ion mobility (IM) mass spectrometry (MS) is used to probe the size, shape, and assembly of biomolecular complexes. IM-IM-MS can increase the amount of…”
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