Search Results - "Buschiazzo, A."

Allostery and protein plasticity: the keystones for bacterial signaling and regulation by Imelio, J. A., Trajtenberg, F., Buschiazzo, A.

“…Bacteria sense intracellular and environmental signals using an array of proteins as antennas. The information is transmitted from such sensory modules to…”
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Volume of interest-based [18F]fluorodeoxyglucose PET discriminates MCI converting to Alzheimer's disease from healthy controls. A European Alzheimer's Disease Consortium (EADC) study by Pagani, M, De Carli, F, Morbelli, S, Öberg, J, Chincarini, A, Frisoni, G B, Galluzzi, S, Perneczky, R, Drzezga, A, van Berckel, B N M, Ossenkoppele, R, Didic, M, Guedj, E, Brugnolo, A, Picco, A, Arnaldi, D, Ferrara, M, Buschiazzo, A, Sambuceti, G, Nobili, F

“…An emerging issue in neuroimaging is to assess the diagnostic reliability of PET and its application in clinical practice. We aimed at assessing the accuracy…”
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Prevalence of interstitial pneumonia suggestive of COVID-19 at 18F-FDG PET/CT in oncological asymptomatic patients in a high prevalence country during pandemic period: a national multi-centric retrospective study by Albano, Domenico, Bertagna, Francesco, Alongi, Pierpaolo, Baldari, Sergio, Baldoncini, Alfonso, Bartolomei, Mirco, Boccaletto, Franco, Boero, Michele, Borsatti, Eugenio, Bruno, Andrea, Burroni, Luca, Capoccetti, Francesca, Castellani, Massimo, Cervino, Anna Rita, Chierichetti, Franca, Ciarmiello, Andrea, Corso, Angelo, Cuocolo, Alberto, De Rimini, Maria Luisa, Deandreis, Desiree’, Dottorini, Massimo Eugenio, Esposito, Filomena, Farsad, Mohsen, Gasparini, Massimo, Grana, Chiara Maria, Gregianin, Michele, Guerra, Luca, Loreti, Fabio, Lupi, Andrea, Martino, Gianluigi, Milan, Elisa, Modoni, Sergio, Morbelli, Silvia, Muni, Alfredo, Nicolai, Emanuele, Palumbo, Barbara, Papa, Sergio, Papaleo, Alberto, Pellerito, Riccardo, Poti, Carlo, Romano, Pasquale, Rossetti, Claudio, Rossini, Pierluigi, Rubini, Giuseppe, Ruffini, Livia, Sacchetti, Gianmauro, Savelli, Giordano, Schiavariello, Saverio, Sciagrà, Roberto, Sciuto, Rosa, Seregni, Ettore, Sestini, Stelvio, Sicolo, Michele, Spanu, Angela, Storto, Giovanni, Balducci, Massimo Tosti, Trifirò, Giuseppe, Versari, Annibale, Vignati, Alberto, Volterrani, Duccio, Calcagni, Maria Lucia, Marzola, Maria Cristina, Garufo, Antonio, Evangelista, Laura, Maroldi, Roberto, Schillaci, Orazio, Giubbini, Raffaele

“…Purpose To assess the presence and pattern of incidental interstitial lung alterations suspicious of COVID-19 on fluorine-18-fluorodeoxyglucose positron…”
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Conformational plasticity of a native retroviral capsid revealed by x-ray crystallography by Obal, G., Trajtenberg, F., Carrión, F., Tomé, L., Larrieux, N., Zhang, X., Pritsch, O., Buschiazzo, A.

“…Retroviruses depend on self-assembly of their capsid proteins (core particle) to yield infectious mature virions. Despite the essential role of the retroviral…”
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The crystal structure of the malic enzyme from Candidatus Phytoplasma reveals the minimal structural determinants for a malic enzyme by Alvarez, C. E., Trajtenberg, F., Larrieux, N., Saigo, M., Golic, A., Andreo, C. S., Hogenhout, S. A., Mussi, M. A., Drincovich, M. F., Buschiazzo, A.

“…Phytoplasmas are wall‐less phytopathogenic bacteria that produce devastating effects in a wide variety of plants. Reductive evolution has shaped their genome,…”
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S.26.02 Disturbed brain metabolism and neurotransmitters in Parkinson's disease with mild cognitive impairment by Nobili, F, Arnaldi, D, Picco, A, Buschiazzo, A, Morbelli, S

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Functional imaging in pre-motor Parkinson's disease by Arnaldi, D, Morbelli, S, Picco, A, Ferrara, M, Buschiazzo, A, Famà, F, De Carli, F, Nobili, F

“…Several non motor symptoms (NMS) can precede the onset of the classical motor Parkinson's disease (PD) syndrome. The existence of pre-motor and even…”
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Liver transplantation in systemic lupus erythematosus: case report and review of the literature by Zazzetti, F, Buschiazzo, A, Villamil, FG, Barreira, JC

“…Severe liver involvement requiring liver transplantation is a rare complication in systemic lupus erythematosus (SLE), but very few cases have been reported…”
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Trafficking and homing of systemically administered stem cells: the need for appropriate analysis tools of radionuclide images by Sambuceti, G, Massollo, M, Marini, C, Podestà, M, Cassanelli, C, Morbelli, S, Fiz, F, Buschiazzo, A, Capitanio, S, Augeri, C, Curti, G, Piana, M, Frassoni, F

“…Despite its enormous relevance, homing of hematopoietic stem cells (SCs) remains relatively uncertain due to the limitations of measuring small number of…”
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Structural basis of sialyltransferase activity in trypanosomal sialidases by Buschiazzo, Alejandro, Tavares, Gisele A., Campetella, Oscar, Spinelli, Silvia, Cremona, Marfa L., París, Gastón, Fernanda Amaya, Maria, Frasch, Alberto C.C., Alzari, Pedro M.

“…The intracellular parasite Trypanosoma cruzi, the etiological agent of Chagas disease, sheds a developmentally regulated surface trans‐sialidase, which is…”
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Immunogenicity and adverse events of SARS-CoV-2 vaccine in health workers by Juárez, Vicente, Marina, Gabriela, Ramón, Claudia, Parentis, Mariangeles, Mamaní, Lorena, Rúa, Gustavo A, Crespo Espindola, Maria E, Buschiazzo, Emilio A, Aciar, Mariana M, Belbruno, Leila N, Lecumberri, María B, Ralle, Ana C, Luna Murillo, Juan M, Delgado, Lucía, Miranda Cáceres, Ivanna, Bonnal, Juan P, Guzman, Valeria E, Eddelcop, Bernardo A

“…The aim of this study was to evaluate the adverse effects and immune response associated with IgG anti S1 SAEA-CoV-2 antibodies among healthcare workers at…”
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Probing molecular function of trypanosomal sialidases: single point mutations can change substrate specificity and increase hydrolytic activity by Paris, G, Cremona, M L, Amaya, M F, Buschiazzo, A, Giambiagi, S, Frasch, A C, Alzari, P M

“…Sialidases are present on the surface of several trypanosomatid protozoan parasites. They are highly specific for sialic acid linked in alpha-(2,3) to a…”
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Identification of the gene(s) coding for the trans‐sialidase of Trypanosoma cruzi by Parodi, A.J., Pollevick, G.D., Mautner, M., Buschiazzo, A., Sanchez, D.O., Frasch, A.C.

“…The gene(s) encoding the Trypanosoma cruzi shed‐acute‐phase‐antigen (SAPA) has a 5′ end encoding a region containing two totally and two partially conserved…”
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Medium scale production and purification to homogeneity of a recombinant trans-sialidase from Trypanosoma cruzi by Buschiazzo, A, Frasch, A C, Campetella, O

“…Trypanosoma cruzi, the agent of Chagas' disease, presents an enzyme that catalyzes the transfer of sialic acid among glycoproteins and glycolipids known as…”
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HemR is an OmpR/PhoB‐like response regulator from Leptospira, which simultaneously effects transcriptional activation and repression of key haem metabolism genes by Morero, Natalia R., Botti, Horacio, Nitta, Kazuhiro R., Carrión, Federico, Obal, Gonzalo, Picardeau, Mathieu, Buschiazzo, Alejandro

“…Summary Several Leptospira species cause leptospirosis, the most extended zoonosis worldwide. In bacteria, two‐component systems constitute key signalling…”
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Crystal structure of glycogen synthase: homologous enzymes catalyze glycogen synthesis and degradation by Buschiazzo, Alejandro, Ugalde, Juan E, Guerin, Marcelo E, Shepard, William, Ugalde, Rodolfo A, Alzari, Pedro M

“…Glycogen and starch are the major readily accessible energy storage compounds in nearly all living organisms. Glycogen is a very large branched glucose…”
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The Crystal Structure and Mode of Action of Trans-Sialidase, a Key Enzyme in Trypanosoma cruzi Pathogenesis by Buschiazzo, Alejandro, Amaya, Marı́a F., Cremona, Marı́a L., Frasch, Alberto C., Alzari, Pedro M.

“…Trans-sialidases (TS) are GPI-anchored surface enzymes expressed in specific developmental stages of trypanosome parasites like Trypanosoma cruzi, the…”
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Structural Insights into the Catalytic Mechanism of Trypanosoma cruzi trans-Sialidase by Amaya, Marı́a Fernanda, Watts, Andrew G, Damager, Iben, Wehenkel, Annemarie, Nguyen, Tong, Buschiazzo, Alejandro, Paris, Gastón, Frasch, A.Carlos, Withers, Stephen G, Alzari, Pedro M

“…Sialidases are a superfamily of sialic-acid-releasing enzymes that are of significant interest due to their implication as virulence factors in the…”
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Trypanosoma cruzi Trans-sialidase Operates through a Covalent Sialyl−Enzyme Intermediate:  Tyrosine Is the Catalytic Nucleophile by WATTS, Andrew G., DAMAGER, Iben, AMAYA, Maria L., BUSCHIAZZO, Alejandro, ALZARI, Pedro, FRASCH, Alberto C., WITHERS, Stephen G.

“…Modified sialic acid substrates have been used to label Trypanosoma cruzi trans-sialidase, demonstrating that the enzyme catalyses the transfer of sialic acid…”
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Structural and Kinetic Analysis of Two Covalent Sialosyl-Enzyme Intermediates on Trypanosoma rangeli Sialidase by Watts, Andrew G., Oppezzo, Pablo, Withers, Stephen G., Alzari, Pedro M., Buschiazzo, Alejandro

“…Trypanosoma rangeli sialidase is a glycoside hydrolase (family GH33) that catalyzes the cleavage of α-2→3-linked sialic acid residues from sialoglycoconjugates…”
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