Search Results - "Buschard, K."

Early life treatment with vancomycin propagates Akkermansia muciniphila and reduces diabetes incidence in the NOD mouse by Hansen, C. H. F., Krych, L., Nielsen, D. S., Vogensen, F. K., Hansen, L. H., Sørensen, S. J., Buschard, K., Hansen, A. K.

“…Aims/hypothesis Increasing evidence suggests that environmental factors changing the normal colonisation pattern in the gut strongly influence the risk of…”
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Sulphated galactosylceramide by Buschard, K.

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Caesarean section is associated with an increased risk of childhood-onset type 1 diabetes mellitus: a meta-analysis of observational studies by Cardwell, C. R, Stene, L. C, Joner, G, Cinek, O, Svensson, J, Goldacre, M. J, Parslow, R. C, Pozzilli, P, Brigis, G, Stoyanov, D, Urbonaitė, B, Šipetić, S, Schober, E, Ionescu-Tirgoviste, C, Devoti, G, de Beaufort, C. E, Buschard, K, Patterson, C. C

“…Aims/hypothesis The aim of this study was to investigate the evidence of an increased risk of childhood-onset type 1 diabetes in children born by Caesarean…”
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A gluten‐free diet lowers NKG2D and ligand expression in BALB/c and non‐obese diabetic (NOD) mice by Adlercreutz, E. H., Weile, C., Larsen, J., Engkilde, K., Agardh, D., Buschard, K., Antvorskov, J. C.

“…Summary The interplay between diet and immune parameters which could affect type 1 diabetes (T1D) pathogenesis is not sufficiently clarified. Intestinal…”
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Birthweight and the risk of childhood-onset type 1 diabetes: a meta-analysis of observational studies using individual patient data by Cardwell, C. R., Stene, L. C., Joner, G., Davis, E. A., Cinek, O., Rosenbauer, J., Ludvigsson, J., Castell, C., Svensson, J., Goldacre, M. J., Waldhoer, T., Polanska, J., Gimeno, S. G. A., Chuang, L.-M., Parslow, R. C., Wadsworth, E. J. K., Chetwynd, A., Pozzilli, P., Brigis, G., Urbonaitė, B., Šipetić, S., Schober, E., Ionescu-Tirgoviste, C., de Beaufort, C. E., Stoyanov, D., Buschard, K., Patterson, C. C.

“…Aims/hypothesis We investigated whether children who are heavier at birth have an increased risk of type 1 diabetes. Methods Relevant studies published before…”
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Glucose activation of islets of Langerhans up‐regulates Toll‐like receptor 5: possible mechanism of protection by Weile, C., Josefsen, K., Buschard, K.

“…Summary Toll‐like receptors are pattern‐recognition receptors of the innate immune system that are activated during viral, bacterial or other infections, as…”
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Association between age, IL-10, IFNγ, stimulated C-peptide and disease progression in children with newly diagnosed Type 1 diabetes by Kaas, A., Pfleger, C., Kharagjitsingh, A. V., Schloot, N. C., Hansen, L., Buschard, K., Koeleman, B. P. C., Roep, B. O., Mortensen, H. B., Alizadeh, B. Z.

“…Diabet. Med. 29, 734–741 (2012) Aims  The relation of disease progression and age, serum interleukin 10 (IL‐10) and interferon gamma (IFNγ) and their genetic…”
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The glycolipid sulfatide protects insulin-producing cells against cytokine-induced apoptosis, a possible role in diabetes by Roeske-Nielsen, A., Dalgaard, L. T., Månsson, J.-E., Buschard, K.

“…Aims/hypothesis Cytokine‐induced apoptosis is recognised as a major cause of the decline in β‐cell mass that ultimately leads to type 1 diabetes mellitus…”
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Association of adiponectin, interleukin (IL)-1ra, inducible protein 10, IL-6 and number of islet autoantibodies with progression patterns of type 1 diabetes the first year after diagnosis by Kaas, A, Pfleger, C, Hansen, L, Buschard, K, Schloot, N.C, Roep, B.O, Mortensen, H.B

“…The progression of type 1 diabetes after diagnosis is poorly understood. Our aim was to assess the relation of disease progression of juvenile-onset type 1…”
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Dietary Gluten Reduces the Number of Intestinal Regulatory T Cells in Mice by Ejsing-Duun, M, Josephsen, J, Aasted, B, Buschard, K, Hansen, A.K

“…It is well established that gluten-free diet reduces the incidence of type 1 diabetes mellitus (T1D) in non-obese diabetic (NOD) mice, though the mechanism is…”
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Involvement of sulfatide in beta cells and type 1 and type 2 diabetes by BUST-HARD, K, BLOMQVIST, M, OSTERBYE, T, FREDMAN, P

“…Mammalian tissues express beta-isoforms of glycosphingolipids and, among these, sulfatide (sulphated galactosylceramide) is present in the beta cells, and it…”
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The postnatal growth of the beta-cell mass in pigs by Bock, T, Kyhnel, A, Pakkenberg, B, Buschard, K

“…Studies of the postnatal growth of the beta-cell mass in rats have revealed some unexpected and apparently paradoxical results, the most prominent being a…”
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Glucagon-like peptide I and glucose-dependent insulinotropic polypeptide stimulate Ca2+-induced secretion in rat alpha-cells by a protein kinase A-mediated mechanism by Ding, W. G., Renstrom, E., Rorsman, P., Buschard, K., Gromada, J.

“…Glucagon-like peptide I and glucose-dependent insulinotropic polypeptide stimulate Ca2+-induced secretion in rat alpha-cells by a protein kinase A-mediated…”
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Glucose induces early growth response gene (Egr-1) expression in pancreatic beta cells by JOSEFSEN, K, SØRENSEN, L. R, BUSCHARD, K, BIRKENBACH, M

“…A copy deoxyribonucleic acid (cDNA) clone of the immediate early growth response gene, egr-1 (Krox-24, Zif268, NGFI-1), was isolated through subtractive…”
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Low serum concentration of sulfatide and presence of sulfated lactosylceramid are associated with Type 2 diabetes. The Skaraborg Project by Buschard, K., Fredman, P., Bøg-Hansen, E., Blomqvist, M., Hedner, J., Råstam, L., Lindblad, U.

“…Aims  The glycosphingolipid sulfatide (sulfated galactosyl‐ceramide) increases exocytosis of β‐cell secretory granules, activates KATP‐channels and is thereby…”
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Estimation of number of follicles, volume of colloid and inner follicular surface area in the thyroid gland of rats by Hartoft‐Nielsen, M. L., Rasmussen, Å. K., Feldt‐Rasmussen, U., Buschard, K., Bock, T.

“…Volume is an important variable in assessing the growth and involution of the thyroid gland. The functional unit in the thyroid is the follicle, which consists…”
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Characterisation of sulphonylurea and ATP-regulated K+ channels in rat pancreatic A-cells by Bokvist, K, Olsen, H L, Høy, M, Gotfredsen, C F, Holmes, W F, Buschard, K, Rorsman, P, Gromada, J

“…We have monitored whole-cell and single channel ATP-sensitive K+ (KATP) currents in isolated rat glucagon-secreting pancreatic A-cells. Tolbutamide produced a…”
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Beta-galactosylceramide increases and sulfatide decreases cytokine and chemokine production in whole blood cells by Roeske-Nielsen, A., Fredman, P., Mansson, J.E., Bendtzen, K., Buschard, K.

“…The glycosphingolipid sulfatide and its immediate precursor beta-galactosylceramide (GalCer) are present in the pancreatic beta-cell in equimolar…”
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Reduced frequency of blood group Lewis a−b− in female Type 1 diabetes patients by Kharagjitsingh, A. V., Prinsen, K., Lemkes, H. H. P. J., De Vries, R. R. P., Roep, B. O., Buschard, K.

“…Aims  To examine a disputed association between the Lewis(a−b−) phenotype and Type 1 diabetes (T1D). Methods  Lewis red blood cell phenotyping was performed…”
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Sulfatide promotes the folding of proinsulin, preserves insulin crystals, and mediates its monomerization by Osterbye, T, Jørgensen, K H, Fredman, P, Tranum-Jensen, J, Kaas, A, Brange, J, Whittingham, J L, Buschard, K

“…Sulfatide is a glycolipid that has been associated with insulin-dependent diabetes mellitus. It is present in the islets of Langerhans and follows the same…”
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