Search Results - "Busch, Sarah"
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The role of extracellular matrix in CNS regeneration
Published in Current opinion in neurobiology (01-02-2007)“…Chondroitin sulfate proteoglycans are the principal inhibitory component of glial scars, which form after damage to the adult central nervous system and act as…”
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2
Modulation of the proteoglycan receptor PTPσ promotes recovery after spinal cord injury
Published in Nature (London) (19-02-2015)“…Regeneration and plasticity after spinal cord injury are limited by inhibitory proteoglycans; here, modulation of a receptor for proteoglycans in rats is shown…”
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3
Another Barrier to Regeneration in the CNS: Activated Macrophages Induce Extensive Retraction of Dystrophic Axons through Direct Physical Interactions
Published in The Journal of neuroscience (17-09-2008)“…Injured axons of the adult CNS undergo lengthy retraction from the initial site of axotomy after spinal cord injury. Macrophage infiltration correlates…”
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4
Overcoming Macrophage-Mediated Axonal Dieback Following CNS Injury
Published in The Journal of neuroscience (12-08-2009)“…Trauma to the adult CNS initiates multiple processes including primary and secondary axotomy, inflammation, and glial scar formation that have devastating…”
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PTPσ Is a Receptor for Chondroitin Sulfate Proteoglycan, an Inhibitor of Neural Regeneration
Published in Science (American Association for the Advancement of Science) (23-10-2009)“…Chondroitin sulfate proteoglycans (CSPGs) present a barrier to axon regeneration. However, no specific receptor for the inhibitory effect of CSPGs has been…”
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Entrapment via synaptic-like connections between NG2 proteoglycan+ cells and dystrophic axons in the lesion plays a role in regeneration failure after spinal cord injury
Published in The Journal of neuroscience (03-12-2014)“…NG2 is purportedly one of the most growth-inhibitory chondroitin sulfate proteoglycans (CSPGs) produced after spinal cord injury. Nonetheless, once the severed…”
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Adult NG2+ Cells Are Permissive to Neurite Outgrowth and Stabilize Sensory Axons during Macrophage-Induced Axonal Dieback after Spinal Cord Injury
Published in The Journal of neuroscience (06-01-2010)“…We previously demonstrated that activated ED1+ macrophages induce extensive axonal dieback of dystrophic sensory axons in vivo and in vitro. Interestingly,…”
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Multipotent adult progenitor cells prevent macrophage-mediated axonal dieback and promote regrowth after spinal cord injury
Published in The Journal of neuroscience (19-01-2011)“…Macrophage-mediated axonal dieback presents an additional challenge to regenerating axons after spinal cord injury. Adult adherent stem cells are known to have…”
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Intravenous multipotent adult progenitor cell treatment decreases inflammation leading to functional recovery following spinal cord injury
Published in Scientific reports (19-11-2015)“…Following spinal cord injury (SCI), immune-mediated secondary processes exacerbate the extent of permanent neurological deficits. We investigated the capacity…”
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Chronic Enhancement of the Intrinsic Growth Capacity of Sensory Neurons Combined with the Degradation of Inhibitory Proteoglycans Allows Functional Regeneration of Sensory Axons through the Dorsal Root Entry Zone in the Mammalian Spinal Cord
Published in The Journal of neuroscience (31-08-2005)“…Peripherally conditioned sensory neurons have an increased capacity to regenerate their central processes. However, even conditioned axons struggle in the…”
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Athermal energy loss from x-rays deposited in thin superconducting films on solid substrates
Published in Physical review. B, Condensed matter and materials physics (05-03-2013)“…When energy is deposited in a thin-film cryogenic detector, such as from the absorption of an x-ray, an important feature that determines the energy resolution…”
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Prevention of contrast-induced nephropathy in STEMI patients undergoing primary percutaneous coronary intervention: a systematic review
Published in Journal of interventional cardiology (01-02-2013)“…To evaluate the current prophylactic strategies against CIN in patients with STEMI treated by primary percutaneous coronary intervention. Contrast-induced…”
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13
Prototype phantoms for characterization of ultralow field magnetic resonance imaging
Published in Magnetic resonance in medicine (01-12-2014)“…Purpose Prototype phantoms were designed, constructed, and characterized for the purpose of calibrating ultralow field magnetic resonance imaging (ULF MRI)…”
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Intracoronary and systemic melatonin to patients with acute myocardial infarction: protocol for the IMPACT trial
Published in Danish medical journal (01-02-2014)“…Ischaemia-reperfusion injury following acute myocardial infarctions (AMI) is an unavoidable consequence of the primary percutaneous coronary intervention…”
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15
Reduced Responsiveness to Social Provocation in Autism Spectrum Disorder
Published in Autism research (01-06-2015)“…Deficits in emotion processing and social interaction are prominent symptoms of autism spectrum disorder (ASD). ASD has also been associated with aggressive…”
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Advances in Small Pixel TES-Based X-Ray Microcalorimeter Arrays for Solar Physics and Astrophysics
Published in IEEE transactions on applied superconductivity (01-06-2013)“…We are developing small-pixel transition-edge sensor microcalorimeters for solar physics and astrophysics applications. These large format close-packed arrays…”
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Autonomic Symptoms in Older Adults Are Common and Associated With Health-Related Quality of Life
Published in Frontiers in neurology (23-11-2021)“…Background: Autonomic symptoms are common in older adults, and a large body of literature focusing on age-related diseases shows that autonomic symptoms in…”
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The Magnetically-Tuned Transition-Edge Sensor
Published in Journal of low temperature physics (01-08-2014)“…We present the first measurements on the proposed magnetically-tuned superconducting transition-edge sensor and compare the modified resistive transition with…”
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Magnetically Tuned Superconducting Transition-Edge Sensors
Published in IEEE transactions on applied superconductivity (01-06-2013)“…In this work we present a detector model for superconducting transition-edge sensors (TESs) that includes for the first time the magnetic field dependence of…”
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Time Domain Multiplexed Readout of Magnetically Coupled Calorimeters
Published in IEEE transactions on applied superconductivity (01-06-2013)“…Magnetically coupled calorimeters (MCC) have extremely high potential for X-ray applications. Although very high energy-resolution has been demonstrated, until…”
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