Search Results - "Busbee, Philip B"

Use of natural AhR ligands as potential therapeutic modalities against inflammatory disorders by Busbee, Philip B, Rouse, Michael, Nagarkatti, Mitzi, Nagarkatti, Prakash S

“…The aim of this review is to discuss research involving ligands for the aryl hydrocarbon receptor (AhR) and their role in immunomodulation. While activation of…”
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Natural indoles, indole-3-carbinol (I3C) and 3,3'-diindolylmethane (DIM), attenuate staphylococcal enterotoxin B-mediated liver injury by downregulating miR-31 expression and promoting caspase-2-mediated apoptosis by Busbee, Philip B, Nagarkatti, Mitzi, Nagarkatti, Prakash S

“…Staphylococcal enterotoxin B (SEB) is a potent superantigen capable of inducing inflammation characterized by robust immune cell activation and proinflammatory…”
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Dysregulated TP53 Among PTSD Patients Leads to Downregulation of miRNA let-7a and Promotes an Inflammatory Th17 Phenotype by Busbee, Philip B, Bam, Marpe, Yang, Xiaoming, Abdulla, Osama A, Zhou, Juhua, Ginsberg, Jay Paul Jack, Aiello, Allison E, Uddin, Monica, Nagarkatti, Mitzi, Nagarkatti, Prakash S

“…Post-traumatic stress disorder (PTSD) is a psychiatric disorder and patients diagnosed with PTSD often express other comorbid health issues, particularly…”
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Yin and yang of cannabinoid CB1 receptor: CB1 deletion in immune cells causes exacerbation while deletion in non-immune cells attenuates obesity by Miranda, Kathryn, Becker, William, Busbee, Philip B., Dopkins, Nicholas, Abdulla, Osama A., Zhong, Yin, Zhang, Jiajia, Nagarkatti, Mitzi, Nagarkatti, Prakash S.

“…While blockade of cannabinoid receptor 1 (CB1) has been shown to attenuate diet-induced obesity (DIO), its relative role in different cell types has not been…”
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Resveratrol modulates the gut microbiota to prevent murine colitis development through induction of Tregs and suppression of Th17 cells by Alrafas, Haider Rasheed, Busbee, Philip B., Nagarkatti, Mitzi, Nagarkatti, Prakash S.

“…Inflammatory diseases of the gastrointestinal tract are often associated with microbial dysbiosis. Thus, dietary interactions with intestinal microbiota, to…”
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Resveratrol Downregulates miR‐31 to Promote T Regulatory Cells during Prevention of TNBS‐Induced Colitis by Alrafas, Haider Rasheed, Busbee, Philip B., Nagarkatti, Mitzi, Nagarkatti, Prakash S.

“…Scope Colitis, an inflammatory bowel disease, is associated with aberrant regulation of the colonic mucosal immune system. Resveratrol, a natural plant…”
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AhR Activation Leads to Massive Mobilization of Myeloid-Derived Suppressor Cells with Immunosuppressive Activity through Regulation of CXCR2 and MicroRNA miR-150-5p and miR-543-3p That Target Anti-Inflammatory Genes by Neamah, Wurood Hantoosh, Singh, Narendra P, Alghetaa, Hasan, Abdulla, Osama A, Chatterjee, Saurabh, Busbee, Philip B, Nagarkatti, Mitzi, Nagarkatti, Prakash

“…The compound 2,3,7,8-tetrachlorodibenzo- -dioxin (TCDD), an environmental contaminant, is a potent ligand for aryl hydrocarbon receptor (AhR). In the current…”
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Natural indoles, indole-3-carbinol and 3,3′-diindolymethane, inhibit T cell activation by staphylococcal enterotoxin B through epigenetic regulation involving HDAC expression by Busbee, Philip B., Nagarkatti, Mitzi, Nagarkatti, Prakash S.

“…Staphylococcal enterotoxin B (SEB) is a potent exotoxin produced by the Staphylococcus aureus. This toxin is classified as a superantigen because of its…”
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Indole-3-carbinol prevents colitis and associated microbial dysbiosis in an IL-22-dependent manner by Busbee, Philip B, Menzel, Lorenzo, Alrafas, Haider Rasheed, Dopkins, Nicholas, Becker, William, Miranda, Kathryn, Tang, Chaunbing, Chatterjee, Saurabh, Singh, Udai, Nagarkatti, Mitzi, Nagarkatti, Prakash S

“…Colitis, an inflammatory bowel disease, is caused by a variety of factors, but luminal microbiota are thought to play crucial roles in disease development and…”
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Cannabinoid Receptor Activation on Haematopoietic Cells and Enterocytes Protects against Colitis by Becker, William, Alrafas, Haider Rasheed, Busbee, Philip B, Walla, Michael D, Wilson, Kiesha, Miranda, Kathryn, Cai, Guoshuai, Putluri, Vasanta, Putluri, Nagireddy, Nagarkatti, Mitzi, Nagarkatti, Prakash S

“…Abstract Background and Aims Cannabinoid receptor [CB] activation can attenuate inflammatory bowel disease [IBD] in experimental models and human cohorts…”
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AhR expression on both Rorc-specific immune cells and Vil1-expressing colonic epithelial cells are essential for I3C-mediated protection against colitis by Mitchell, Chandani, Staley, Shanieka, Wilson, Keisha, Rutkovsky, Alex, Wisniewski, Pj, Dopkins, Nicholas, Nagarkatti, Mitzi, Nagarkatti, Prakash, Busbee, Philip B

“…Abstract Colitis is an inflammatory bowel disease (IBD) characterized by dysregulation of the immune system. In our previous reports, we showed…”
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Natural indoles, indole-3-carbinol and 3,3′-diindolymethane, inhibit T cell activation by Staphylococcal Entertoxin B through epigenetic regulation involving HDAC expression by Busbee, Philip B., Nagarkatti, Mitzi, Nagarkatti, Prakash S.

“…Staphylococcal entertoxin B (SEB) is a potent exotoxin produced by the Staphylococcus aureus . This toxin is classified as a superantigen because of its…”
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Natural Indoles, Indole-3-Carbinol (I3C) and 3,3'-Diindolylmethane (DIM), Attenuate Staphylococcal Enterotoxin B-Mediated Liver Injury by Downregulating miR-31 Expression and Promoting Caspase-2-Mediated Apoptosis: e0118506 by Busbee, Philip B, Nagarkatti, Mitzi, Nagarkatti, Prakash S

“…Staphylococcal enterotoxin B (SEB) is a potent superantigen capable of inducing inflammation characterized by robust immune cell activation and proinflammatory…”
Get full text