Search Results - "Busardo, Francesco P"

3F-α-pyrrolydinovalerophenone (3F-α-PVP) in vitro human metabolism: Multiple in silico predictions to assist in LC-HRMS/MS analysis and targeted/untargeted data mining by Carlier, Jeremy, Berardinelli, Diletta, Montanari, Eva, Sirignano, Ascanio, Di Trana, Annagiulia, Busardò, Francesco P.

“…•3F-α-PVP metabolic fate was characterized with human hepatocyte incubations.•LC-HRMS/MS and targeted/untargeted data mining was used to analyze the…”
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A Review of Synthetic Cathinone–Related Fatalities From 2017 to 2020 by La Maida, Nunzia, Di Trana, Annagiulia, Giorgetti, Raffaele, Tagliabracci, Adriano, Busardò, Francesco P., Huestis, Marilyn A.

“…Synthetic cathinones (SCs) are designer analogs of the natural active principle of khat. Since their appearance on the black market in 2003, their popularity…”
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GHB Pharmacology and Toxicology: Acute Intoxication, Concentrations in Blood and Urine in Forensic Cases and Treatment of the Withdrawal Syndrome by Busardo, Francesco, Jones, Alan

“…The illicit recreational drug of abuse, γ-hydroxybutyrate (GHB) is a potent central nervous system depressant and is often encountered during forensic…”
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Pharmacotoxicology of Non-fentanyl Derived New Synthetic Opioids by Solimini, Renata, Pichini, Simona, Pacifici, Roberta, Busardò, Francesco P, Giorgetti, Raffaele

“…A class of opioid agonists not structurally related to fentanyl, derived from research publications of pharmaceutical companies or patents within the United…”
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Human metabolism of four synthetic benzimidazole opioids: isotonitazene, metonitazene, etodesnitazene, and metodesnitazene by Taoussi, Omayema, Berardinelli, Diletta, Zaami, Simona, Tavoletta, Francesco, Basile, Giuseppe, Kronstrand, Robert, Auwärter, Volker, Busardò, Francesco P., Carlier, Jeremy

“…Following isotonitazene scheduling in 2019, the availability of alternative 2-benzylbenzimidazole opioids (nitazenes) on the global drug market increased,…”
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Pyrrolidinyl Synthetic Cathinones α-PHP and 4F-α-PVP Metabolite Profiling Using Human Hepatocyte Incubations by Carlier, Jeremy, Diao, Xingxing, Giorgetti, Raffaele, Busardò, Francesco P, Huestis, Marilyn A

“…For more than ten years, new synthetic cathinones (SCs) mimicking the effects of controlled cocaine-like stimulants have flooded the illegal drug market,…”
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In silico, in vitro, and in vivo human metabolism of acetazolamide, a carbonic anhydrase inhibitor and common “diuretic and masking agent” in doping by Busardò, Francesco P., Lo Faro, Alfredo F., Sirignano, Ascanio, Giorgetti, Raffaele, Carlier, Jeremy

“…Acetazolamide (ACZ) is a carbonic anhydrase inhibitor prescribed for the treatment of various pathologies. It is also used in doping and is prohibited in and…”
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Adulteration Practices of Psychoactive Illicit Drugs: An Updated Review by Solimini, Renata, Rotolo, Maria C, Pellegrini, Manuela, Minutillo, Adele, Pacifici, Roberta, Busardò, Francesco P, Zaami, Simona

“…Powdery drugs such as cocaine and heroin are frequently adulterated or diluted predominantly to obtain more doses and to increase the drug dealer's profits,…”
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Anabolic Androgenic Steroid (AAS) Related Deaths: Autoptic, Histopathological and Toxicological Findings by Frati, Paola, Busardo, Francesco, Cipolloni, Luigi, Dominicis, Enrico, Fineschi, Vittorio

“…Anabolic androgenic steroids (AASs) represent a large group of synthetic derivatives of testosterone, produced to maximize anabolic effects and minimize the…”
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Metabolism and detection of designer benzodiazepines: a systematic review by Gameli, Prince S, Huestis, Marilyn A, Balloni, Aurora, Busardò, Francesco P, Carlier, Jeremy

“…Synthesis and illicit use of designer benzodiazepines are growing concerns, with these new psychoactive substances (NPS) posing serious health consequences and…”
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European Drug Users at Risk from Illicit Fentanyls Mix by Pichini, Simona, Pacifici, Roberta, Marinelli, Enrico, Busardò, Francesco P

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Neurological Aspects of Medical Use of Cannabidiol by Mannucci, Carmen, Navarra, Michele, Calapai, Fabrizio, Spagnolo, Elvira V, Busardò, Francesco P, Cas, Roberto D, Ippolito, Francesca M, Calapai, Gioacchino

“…Cannabidiol (CBD) is among the major secondary metabolites of Cannabis devoid of the delta-9-tetra-hydrocannabinol psychoactive effects. It is a…”
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Twelve months monitoring of hair GHB decay following a single dose administration in a case of facilitated sexual assault by Busardò, Francesco P., Vaiano, Fabio, Mannocchi, Giulio, Bertol, Elisabetta, Zaami, Simona, Marinelli, Enrico

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Monitoring Perinatal Exposure to Cannabis and Synthetic Cannabinoids by Carlier, Jeremy, Huestis, Marilyn A., Zaami, Simona, Pichini, Simona, Busardò, Francesco P.

“…Drug use during pregnancy is a critical global challenge, capable of severe impacts on neonatal development. However, the consumption of cannabis and synthetic…”
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Enhancing the sensitivity of the LC-MS/MS detection of propofol in urine and blood by azo-coupling derivatization by Vaiano, Fabio, Mari, Francesco, Busardò, Francesco P., Bertol, Elisabetta

“…Propofol is a low-polarity, volatile molecule that is difficult for an electrospray ion source (ESI) to ionize in either negative ion mode (NIM) or positive…”
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3-CMC, 4-CMC, and 4-BMC Human Metabolic Profiling: New Major Pathways to Document Consumption of Methcathinone Analogues? by Berardinelli, Diletta, Taoussi, Omayema, Daziani, Gloria, Tavoletta, Francesco, Ricci, Giovanna, Tronconi, Livio P., Adamowicz, Piotr, Busardò, Francesco P., Carlier, Jeremy

“…Synthetic cathinones represent one of the largest and most abused new psychoactive substance classes, and have been involved in numerous intoxications and…”
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Testing Unconventional Matrices to Monitor for Prenatal Exposure to Heroin, Cocaine, Amphetamines, Synthetic Cathinones, and Synthetic Opioids by Carlier, Jeremy, La Maida, Nunzia, Di Trana, Annagiulia, Huestis, Marilyn A., Pichini, Simona, Busardò, Francesco P.

“…The prevalence of drug use during pregnancy continues to increase despite the associated serious adverse obstetrical outcomes, including increased risk of…”
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Biomarkers of 4-hydroxy- N,N -methylpropyltryptamine (4-OH-MPT) intake identified from human hepatocyte incubations by Carlier, Jeremy, Malaca, Sara, Huestis, Marilyn A, Tagliabracci, Adriano, Tini, Anastasio, Busardò, Francesco P

“…4-Hydroxy- -methylpropyltryptamine (4-OH-MPT) is a psychedelic tryptamine whose use is regulated in several countries. Due to unspecific effects, consumption…”
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Advances in Forensic Toxicology by Malaca, Sara, Carlier, Jeremy, Busardò, Francesco P

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Monitoring Prenatal Exposure to Buprenorphine and Methadone by Di Trana, Annagiulia, La Maida, Nunzia, Tittarelli, Roberta, Huestis, Marilyn A., Pichini, Simona, Busardò, Francesco P., Carlier, Jeremy

“…Buprenorphine and methadone are international gold standards for managing opioid use disorders. Although they are efficacious in treating opioid dependence,…”
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