Search Results - "Burzynski, Laura C"

Alternative Pathways of IL-1 Activation, and Its Role in Health and Disease by Pyrillou, Katerina, Burzynski, Laura C, Clarke, Murray C H

“…Cytokines activate or inhibit immune cell behavior and are thus integral to all immune responses. IL-1α and IL-1β are powerful apical cytokines that instigate…”
Get full text

The Coagulation and Immune Systems Are Directly Linked through the Activation of Interleukin-1α by Thrombin by Burzynski, Laura C., Humphry, Melanie, Pyrillou, Katerina, Wiggins, Kimberley A., Chan, Julie N.E., Figg, Nichola, Kitt, Lauren L., Summers, Charlotte, Tatham, Kate C., Martin, Paul B., Bennett, Martin R., Clarke, Murray C.H.

“…Ancient organisms have a combined coagulation and immune system, and although links between inflammation and hemostasis exist in mammals, they are indirect and…”
Get full text

Thrombin-activated interleukin-1α drives atherogenesis, but also promotes vascular smooth muscle cell proliferation and collagen production by Burzynski, Laura C, Morales-Maldonado, Alejandra, Rodgers, Amanda, Kitt, Lauren A, Humphry, Melanie, Figg, Nichola, Bennett, Martin R, Clarke, Murray C H

“…Abstract Aims Atherosclerosis is driven by multiple processes across multiple body systems. For example, the innate immune system drives both atherogenesis and…”
Get full text

Death Is Coming and the Clot Thickens, as Pyroptosis Feeds the Fire by Burzynski, Laura C., Clarke, Murray C.H.

“…Pyroptotic cell death during endotoxemia causes death via unknown mechanisms. In this issue of Immunity, Wu et al. (2019) show that T3SS rod proteins or LPS…”
Get full text

Interleukin-1α Activity in Necrotic Endothelial Cells Is Controlled by Caspase-1 Cleavage of Interleukin-1 Receptor-2: IMPLICATIONS FOR ALLOGRAFT REJECTION by Burzynski, Laura C, Humphry, Melanie, Bennett, Martin R, Clarke, Murray C H

“…Inflammation is a key instigator of the immune responses that drive atherosclerosis and allograft rejection. IL-1α, a powerful cytokine that activates both…”
Get full text

Interleukin-1α Activity in Necrotic Endothelial Cells Is Controlled by Caspase-1 Cleavage of Interleukin-1 Receptor-2 by Burzynski, Laura C., Humphry, Melanie, Bennett, Martin R., Clarke, Murray C.H.

“…Inflammation is a key instigator of the immune responses that drive atherosclerosis and allograft rejection. IL-1α, a powerful cytokine that activates both…”
Get full text

Platelet Isolation and Activation Assays by Burzynski, Laura C, Pugh, Nicholas, Clarke, Murray C H

“…Platelets regulate hemostasis and are the key determinants of pathogenic thrombosis following atherosclerotic plaque rupture. Platelets circulate in an…”
Get full text

Sensory Signalling in Mice Lacking the Serotonin Transporter (SERT) by Keating, Christopher D, Burzynski, Laura C, Gershon, Michael D, Grundy, David

Get full text