Search Results - "Bury, Aleksandra E"
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Reduction in PA28αβ activation in HD mouse brain correlates to increased mHTT aggregation in cell models
Published in PloS one (01-12-2022)“…Huntington's disease is an autosomal dominant heritable disorder caused by an expanded CAG trinucleotide repeat at the N-terminus of the Huntingtin (HTT) gene…”
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Development of a Light-Dependent Protein Histidine Kinase
Published in Methods in molecular biology (Clifton, N.J.) (2020)“…Phosphorylation plays a critical role in facilitating signal transduction in prokaryotic and eukaryotic organisms. Our study introduces a tool for…”
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Global Proteome and Ubiquitinome Changes in the Soluble and Insoluble Fractions of Q175 Huntington Mice Brains[S]
Published in Molecular & cellular proteomics (01-09-2019)“…Label-free quantitative mass spectrometry techniques were applied to discover proteome and ubiquitinome changes in brain tissue of Huntington's disease mouse…”
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Insulin-Degrading Enzyme Efficiently Degrades polyQ Peptides but not Expanded polyQ Huntingtin Fragments
Published in Journal of Huntington's disease (01-01-2024)“…Huntington's disease is an inheritable autosomal dominant disorder caused by an expanded CAG trinucleotide repeat within the Huntingtin gene, leading to a…”
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5
Reduction in PA28[alpha][beta] activation in HD mouse brain correlates to increased mHTT aggregation in cell models
Published in PloS one (27-12-2022)“…Huntington's disease is an autosomal dominant heritable disorder caused by an expanded CAG trinucleotide repeat at the N-terminus of the Huntingtin (HTT) gene…”
Get full text
Journal Article -
6
Global Proteome and Ubiquitinome Changes in the Soluble and Insoluble Fractions of Q175 Huntington Mice Brains
Published in Molecular & cellular proteomics (01-09-2019)“…Huntington's disease is caused by a polyglutamine repeat expansion in the huntingtin protein which affects the function and folding of the protein, and results…”
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Journal Article