Search Results - "Burton, Donald J."

Site-Specific Preparation of 2-Carboalkoxy-4-substituted Naphthalenes and 9-Alkylphenanthrenes and Evidence for an Allene Intermediate in the Novel Base-Catalyzed Cyclization of 2-Alkynylbiphenyls by Wang, Yi, Burton, Donald J

“…A site-specific preparation of 2-carboalkoxy-4-substituted naphthalenes and 9-alkylphenanthrenes is described. The successful cyclization of an allene…”
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A Facile, General Synthesis of 3,4-Difluoro-6-substituted-2-pyrones by Wang, Yi, Burton, Donald J

“…Reaction of (2E)-2,3-difluoro-3-iodoacrylic acid with a variety of terminal acetylenes under cocatalysis of PdCl2(PPh3)2 and CuI gave difluorinated 2-pyrones…”
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Unusual photocyclization of perfluoro cis-1,2-dimethyl-1,3-butadienyl benzenes as a means to synthesize partially fluorinated naphthalenes by Yamamoto, Michiharu, Swenson, Dale C., Burton, Donald J.

“…The preparation of perfluoro cis-1,2-dimethyl butadienyl copper reagent and subsequent coupling with aryl iodides are described. Photocyclization of the…”
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A Simple, Two-Step, Site-Specific Preparation of Fluorinated Naphthalene and Phenanthrene Derivatives from Fluorobromo-Substituted Alkenes by Wang, Yi, Xu, Jianjun, Burton, Donald J

“…A facile two-step procedure for the site-specific preparation of fluorinated naphthalene and phenanthrene derivatives is described. The Sonogashira reaction of…”
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Site-Specific Preparation of 3-Fluoro-1-substituted-naphthalenes via a Novel Base-Catalyzed Cyclization Reaction from (E)-Monofluoroenynes by Xu, Jianjun, Wang, Yi, Burton, Donald J

“…A novel cyclization reaction for the preparation of 3-fluoro-1-substituted-naphthalenes is reported. (E)-Monofluoroenynes, which are prepared by Sonogashira…”
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Room Temperature Preparation of Trifluoroethenylzinc Reagent by Metalation of the Readily Available Halocarbon HFC-134a and an Efficient, Economically Viable Synthesis of 1,2,2-Trifluorostyrenes by Raghavanpillai, Anilkumar, Burton, Donald J

“…Trifluoroethenylzinc reagent [CF2CFZnX] was generated from the readily available halocarbon HFC-134a by an in situ metalation−transmetalation procedure at…”
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Approaches to the preparation of (Z)-1,2-difluorostilbenes by Burton, Donald J., Wesolowski, C.A., Liu, Qibo, Davis, Charles R.

“…Methodology directed at the preparation of (Z)-1,2-difluorostilbenes has been evaluated. For symmetrical (Z)-1,2-difluorostilbenes, photochemical isomerization…”
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Stereospecific synthesis of unsymmetrical (E)- and (Z)-1,2-difluorostilbenes by Lim, Chongsoo, Wang, Yi, Burton, Donald J.

“…[Display omitted] A methodology was developed for the synthesis and purification of unsymmetrical (E)- or (Z)-1,2-difluorostilbenes using 1,4-dioxane, which…”
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A New Route for the Preparation of Substituted 2,2-Difluorostyrenes and a Convenient Route to Substituted (2,2,2-Trifluoroethyl)benzenes by Nguyen, Ba V, Burton, Donald J

“…The (2,2-difluoroethenyl)zinc reagent II is coupled with aryl iodides or bromides in the presence of Pd(PPh3)4 in DMF to give the corresponding…”
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Stereospecific synthesis of (E)- and (Z)-1-chloro-1,2-difluorostyrenes by Lim, Chongsoo, Burton, Donald J.

“…(Z)-2-chloro-1,2-difluoro-1-iodoethene and the (E)-2-chloro-1,2-difluoro-1-iodoethene react with activated zinc at 50°C to stereospecifically generate the…”
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An improved, efficient route to 2,2-difluoroethenylbenzenes by Lu, Long, Burton, Donald J.

“…Treatment of vinylidene fluoride with tert-BuLi at −115 °C gave a solution of [F 2C CHLi]. Addition of Bu 3SnCl to this lithium reagent at −110 °C gave an 88%…”
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Synthetic and mechanistic aspects of halo-F-methylphosphonates by Flynn, Richard M., Burton, Donald J.

“…[Display omitted] ► Trialkylphosphites react with halo-F-methanes to afford halo-F-methylphosphonates. ► Mechanistically, the reaction involves halophilic…”
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The stereoselective synthesis of (Z)-HFC CFZnI and stereospecific preparation of (E)-1,2-difluorostyrenes from (Z)-HFC CFZnI via an unusual Pd(PPh3)4–Cu(I)Br co-catalysis approach or (Z)-HFC CFSnBu3 by Liu, Qibo, Burton, Donald J.

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Copper(I)-Only Catalyzed Reactions of (E)-2,3-Difluoro-3-stannylacrylic Ester with Acid Chlorides and Mechanistic Studies of the “Copper Effect” in Stille Coupling Reactions by Wang, Yi, Burton, Donald J

“…The reactions of (E)-2,3-difluoro-3-stannylacrylic ester with acid chlorides under catalysis of CuI stereospecifically afforded ethyl…”
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Chemoselective halogenation of 2-hydroperfluoroalkyl aldehydes by Wiebe, Donald A., Burton, Donald J.

“…Free-radical chlorination or bromination of 2-hydroperfluoroalkyl aldehydes chemoselectively affords the corresponding acyl halide. Only the formyl hydrogen is…”
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Preparation of E-(1,2-difluoro-1,2-ethenediyl)bis(tributylstannane) by Liu, Qibo, Burton, Donald J.

“…Chlorotrifluoroethene is converted in situ to [F 2C CFSiMe 3]. The crude [F 2C CFSiMe 3] solution is reduced with lithium aluminum hydride to (HFC CFSiMe 3),…”
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Synthesis of new fluorinated synthons: (E and Z) ClFCCFI and (E and Z) BrFCCFI by Lim, Chongsoo, Wesolowski, Craig A., Burton, Donald J.

“…Trifluorovinyl(trimethyl)silane can be prepared from the trifluorovinyl zinc reagent in DMF in 74% isolated yield. This silane can be reduced by LAH to give…”
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New Efficient Approach to 2,2-Diaryl-1,1-difluoro-1-alkenes and 1,1-Difluoro-2-aryl-1,3-dienes via Suzuki Coupling of α-Halo-β,β-difluorostyrenes by Raghavanpillai, Anilkumar, Burton, Donald J

“…α-Halo-β,β-difluorostyrenes [ArCX = CF2; X = Br, I; Ar = aryl, heteroaryl; synthesized by the Pd(0)-catalyzed coupling reaction of the corresponding…”
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A Novel Stereospecific Route to (E)- and (Z)-(2-Substituted-1,2-difluoroethenyl)stannanes by Xue, Ling, Lu, Long, Pedersen, Scot D, Liu, Qibo, Narske, Robert M, Burton, Donald J

“…In the presence of 1.2−1.5 equiv of potassium fluoride, a variety of (E)- and (Z)-(2-substituted-1,2-difluoroethenyl)silanes reacted with tributyltin chloride…”
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Synthesis of .alpha.,.alpha.-Difluoro-Functionalized Ketones by Qiu, Zai-Ming, Burton, Donald J

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