Search Results - "Burslem, Frank"

Assessing the phenotypic effects in the general population of rare variants in genes for a dominant Mendelian form of diabetes by Flannick, Jason, Beer, Nicola L, Bick, Alexander G, Agarwala, Vineeta, Molnes, Janne, Gupta, Namrata, Burtt, Noël P, Florez, Jose C, Meigs, James B, Taylor, Herman, Lyssenko, Valeriya, Irgens, Henrik, Fox, Ervin, Burslem, Frank, Johansson, Stefan, Brosnan, M Julia, Trimmer, Jeff K, Newton-Cheh, Christopher, Tuomi, Tiinamaija, Molven, Anders, Wilson, James G, O'Donnell, Christopher J, Kathiresan, Sekar, Hirschhorn, Joel N, Njølstad, Pål R, Rolph, Tim, Seidman, J G, Gabriel, Stacey, Cox, David R, Seidman, Christine E, Groop, Leif, Altshuler, David

“…David Altshuler and colleagues sequenced seven genes for maturity-onset diabetes of the young (MODY), a dominant Mendelian disorder, in 4,003 individuals drawn…”
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Analysis of the acute and chronic wound environments: the role of proteases and their inhibitors by Trengove, Naomi J., Stacey, Michael C., Macauley, Shawn, Bennett, Neil, Gibson, Jane, Burslem, Frank, Murphy, Gillian, Schultz, Gregory

“…To assess the differences in proteolytic activity of acute and chronic wound environments, wound fluids were collected from acute surgical wounds (22 samples)…”
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Analysis of the Ultraviolet B Response in Primary Human Keratinocytes Using Oligonucleotide Microarrays by Sesto, Angela, Navarro, Manuel, Burslem, Frank, Jorcano, José L.

“…UV radiation is the most important environmental skin aggressor, causing cancer and other problems. This paper reports the use of oligonucleotide microarray…”
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The Psoriatic Transcriptome Closely Resembles That Induced by Interleukin-1 in Cultured Keratinocytes: Dominance of Innate Immune Responses in Psoriasis by Mee, John B, Johnson, Claire M, Morar, Nilesh, Burslem, Frank, Groves, Richard W

“…Psoriasis has been considered an autoimmune, T cell-mediated disorder in which adaptive immune responses predominate over those of non-antigen-specific innate…”
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GPIb-dependent platelet activation is dependent on Src kinases but not MAP kinase or cGMP-dependent kinase by Marshall, Stuart J., Senis, Yotis A., Auger, Jocelyn M., Feil, Robert, Hofmann, Franz, Salmon, Gary, Peterson, J. Thomas, Burslem, Frank, Watson, Steve P.

“…Glycoprotein Ib-IX-V (GPIb-IX-V) mediates platelet tethering to von Willebrand factor (VWF), recruiting platelets into the thrombus, and activates integrin…”
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Wound healing and inflammation genes revealed by array analysis of 'macrophageless' PU.1 null mice by Cooper, Lisa, Johnson, Claire, Burslem, Frank, Martin, Paul

“…Wound healing is a complex process requiring the collaborative efforts of different tissues and cell lineages, and involving the coordinated interplay of…”
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The Psoriatic Transcriptome Closely Resembles That Induced by Interleukin-1 in Cultured Keratinocytes by Mee, John B, Johnson, Claire M, Morar, Nilesh, Burslem, Frank, Groves, Richard W

“…Psoriasis has been considered an autoimmune, T cell-mediated disorder in which adaptive immune responses predominate over those of non-antigen-specific innate…”
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Gene expression profiling of wound healing in keratinocytes using DNA microarrays by Johnson, Claire, Burslem, Frank, Lanfear, Jerry

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Selectivity of inhibition of matrix metalloproteases MMP-3 and MMP-2 by succinyl hydroxamates and their carboxylic acid analogues is dependent on P3′ group chirality by Fray, M.Jonathan, Burslem, M.Frank, Dickinson, RogerP

“…Structure–activity relationships are described for a series of succinyl hydroxamic acids 1a– o and their carboxylic acid analogues 2a– o as inhibitors of…”
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