Search Results - "Burroughs, K. D."

Dysregulation of IGF-I signaling in uterine leiomyoma by Burroughs, KD, Howe, SR, Okubo, Y, Fuchs-Young, R, LeRoith, D, Walker, CL

“…IGF-I expression has been observed in human uterine leiomyomas. To examine whether autocrine IGF-I signaling plays a role in the growth of these tumors, we…”
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Altered Hormonal Responsiveness of Proliferation and Apoptosis During Myometrial Maturation and the Development of Uterine Leiomyomas in the Rat by BURROUGHS, Kevin D, FUCHS-YOUNG, Robin, DAVIS, Barbara, WALKER, Cheryl L

“…Uterine leiomyomas are responsive to the ovarian steroids, estrogen and progesterone; however, a mechanistic understanding of the role of these hormones in the…”
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Insulin-Like Growth Factor-I: a Key Regulator of Human Cancer Risk? by Burroughs, Kevin D., Dunn, Sandra E., Barrett, J. Carl, Taylor, Jack A.

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Efficacy of LGD1069 (Targretin), a retinoid X receptor-selective ligand, for treatment of uterine leiomyoma by Gamage, S D, Bischoff, E D, Burroughs, K D, Lamph, W W, Gottardis, M M, Walker, C L, Fuchs-Young, R

“…The conventional treatment of uterine leiomyomas, or fibroids, with gonadotropin-releasing hormone (GnRH) agonists is often associated with serious side…”
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Regulation of apoptosis in uterine leiomyomata by Burroughs, K D, Kiguchi, K, Howe, S R, Fuchs-Young, R, Trono, D, Barrett, J C, Walker, C

“…Tumors developing from hormone-dependent tissues, such as the breast and prostate, have been successfully treated in the clinic by methods of hormone ablation,…”
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Potentiation of oncolytic adenoviral vector efficacy with gutless vectors encoding GMCSF or TRAIL by Burroughs, Kevin D, Kayda, Dawn B, Sakhuja, Kiran, Hudson, Yvette, Jakubczak, John, Bristol, J Andrew, Ennist, David, Hallenbeck, Paul, Kaleko, Michael, Connelly, Sheila

“…Oncolytic adenoviral vectors selectively replicate in and lyse human tumor cells, providing a promising means for targeted tumor destruction. However,…”
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Phase I trial of Seneca Valley Virus (NTX-010), a newly discovered systemically deliverable oncolytic picornavirus, in patients with solid tumors with neuroendocrine features by Rudin, C. M., Lansey, D., Burroughs, K. D., Hales, L. M., Neefe, J. R., Reddy, P. S., Hallenbeck, P. L.

“…Abstract only 18014 Background: NTX-010 is a replication-competent cytolytic picornavirus with selective tropism for cancers with neuroendocrine features…”
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Preclinical evidence for therapeutic efficacy of selective estrogen receptor modulators for uterine leiomyoma by Walker, C L, Burroughs, K D, Davis, B, Sowell, K, Everitt, J I, Fuchs-Young, R

“…Uterine leiomyoma are the most common gynecologic neoplasm and a primary cause of hysterectomy in premenopausal women. Preclinical studies were conducted in…”
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Phosphatidylinositol 3-Kinase and Mek1/2 Are Necessary for Insulin-Like Growth Factor-I-Induced Vascular Endothelial Growth Factor Synthesis in Prostate Epithelial Cells: A Role for Hypoxia-Inducible Factor-1? by BURROUGHS, Kevin D, OH, Jennifer, BARRETT, J. Carl, DIAUGUSTINE, Richard P

“…Due to the importance of vascular endothelial growth factor (VEGF) in the neovascularization of solid tumors, a clear understanding of how VEGF is regulated in…”
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