Search Results - "Burr, Stephanie D"

Replacement of saturated fatty acids with linoleic acid in western diet attenuates atherosclerosis in a mouse model with inducible ablation of hepatic LDL receptor by Burr, Stephanie D., Chen, Yongbin, Hartley, Christopher P., Zhao, Xianda, Liu, Jun

“…Dietary saturate fatty acids (SFAs) have been consistently linked to atherosclerosis and obesity, both of which are characterized by chronic inflammation and…”
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PNPLA3 is a triglyceride lipase that mobilizes polyunsaturated fatty acids to facilitate hepatic secretion of large-sized very low-density lipoprotein by Johnson, Scott M., Bao, Hanmei, McMahon, Cailin E., Chen, Yongbin, Burr, Stephanie D., Anderson, Aaron M., Madeyski-Bengtson, Katja, Lindén, Daniel, Han, Xianlin, Liu, Jun

“…The I148M variant of PNPLA3 is closely associated with hepatic steatosis. Recent evidence indicates that the I148M mutant functions as an inhibitor of…”
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Rap1a Activity Elevated the Impact of Endogenous AGEs in Diabetic Collagen to Stimulate Increased Myofibroblast Transition and Oxidative Stress by Burr, Stephanie D, Dorroh, Christopher C, Stewart, Jr, James A

“…Diabetics have an increased risk for heart failure due to cardiac fibroblast functional changes occurring as a result of AGE/RAGE signaling. Advanced glycation…”
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Rap1a Overlaps the AGE/RAGE Signaling Cascade to Alter Expression of α-SMA, p-NF-κB, and p-PKC-ζ in Cardiac Fibroblasts Isolated from Type 2 Diabetic Mice by Burr, Stephanie D, Stewart, Jr, James A

“…Cardiovascular disease, specifically heart failure, is a common complication for individuals with type 2 diabetes mellitus. Heart failure can arise with…”
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Rap1a Regulates Cardiac Fibroblast Contraction of 3D Diabetic Collagen Matrices by Increased Activation of the AGE/RAGE Cascade by Burr, Stephanie D., Stewart, James A.

“…Cardiovascular disease is a common diabetic complication that can arise when cardiac fibroblasts transition into myofibroblasts. Myofibroblast transition can…”
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The Impact of Diabetic Conditions and AGE/RAGE Signaling on Cardiac Fibroblast Migration by Burr, Stephanie D, Harmon, Mallory B, Jr, James A Stewart

“…Diabetic individuals have an increased risk for developing cardiovascular disease due to stiffening of the left ventricle (LV), which is thought to occur, in…”
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A novel gene's role in an ancient mechanism: secreted Frizzled-related protein 1 is a critical component in the anterior-posterior Wnt signaling network that governs the establishment of the anterior neuroectoderm in sea urchin embryos by Khadka, Anita, Martínez-Bartolomé, Marina, Burr, Stephanie D, Range, Ryan C

“…The anterior neuroectoderm (ANE) in many deuterostome embryos (echinoderms, hemichordates, urochordates, cephalochordates, and vertebrates) is progressively…”
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Extracellular matrix components isolated from diabetic mice alter cardiac fibroblast function through the AGE/RAGE signaling cascade by Burr, Stephanie D., Stewart, James A.

“…Individuals suffering from diabetes have an increased risk of developing cardiovascular complications such as heart failure. Heart failure can be a result of…”
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The Power of Simplicity: Sea Urchin Embryos as in Vivo Developmental Models for Studying Complex Cell-to-cell Signaling Network Interactions by Range, Ryan C, Martinez-Bartolomé, Marina, Burr, Stephanie D

“…Remarkably few cell-to-cell signal transduction pathways are necessary during embryonic development to generate the large variety of cell types and tissues in…”
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Abstract 161: Ablation Of Intracellular Lipolytic Inhibitor G0S2 Promotes Vascular Lipolysis And Alleviates Diet-induced Atherosclerosis by Chen, Yongbin, Johnson, Scott M, Burr, Stephanie D, Povero, Davide, McMahon, Cailin E, Liu, Jun

“…Abstract only Adipose tissue plays a central role in the regulation of plasma triglyceride (TG) and fatty acid (FA) levels, whose elevation is associated with…”
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Rap1a Overlaps the AGE/RAGE Signaling Cascade in Type 2 Diabetes Mellitus by Burr, Stephanie D

“…Diabetic individuals have an increased risk for developing cardiovascular disease due to stiffening of the left ventricle, which is thought to occur, in part,…”
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The Power of Simplicity: Sea Urchin Embryos as in Vivo Developmental Models for Studying Complex Cell-to-cell Signaling Network Interactions by Range, Ryan C., Martinez-Bartolomé, Marina, Burr, Stephanie D.

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