Search Results - "Burova, L A"

Major pathogenicity factors of Streptococcus pyogenes by Burova, L. A., Totolian, A. A.

“…Streptococcal diseases and their complications are among the global problems of international health. S. pyogenes (group A streptococci — GAS) is a pathogen…”
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Mechanisms of Antiproliferative Effect of Streptococcal Arginine Deiminase on Jurkat Lymphoblastic Leukemia Cells by Starikova, E. A., Mammedova, J. T., Ozhiganova, A., Burova, L. A., Kudryavtsev, I. V.

“…Arginine deprivation strategy is considered as a promising trend in cancer therapy. The aim of the study was to investigate the influence of streptococcal…”
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Streptococcus pyogenes: phenomenon of nonimmune binding of human immunoglobulins and its role in pathology by Burova, L. A., Suvorov, A. N., Totolian, A. A.

“…M and M-like proteins represent the main pathogenicity factors of Streptococcus pyogenes, a widely spread and potentially lethal bacterial pathogen. These…”
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Effect of streptococcal arginine deiminase on the function of CD4+ and CD8+T lymphocytes by Starikova, E. A., Mammedova, J. T., Ozhiganova, A., Lebedeva, A. M., Leveshko, T. A., Burova, L. A., Kudryavtsev, I. V.

“…Arginine metabolism plays an important role in regulating the functions of immune cells in mammals. Pathogenic microbes use the mechanism of arginine depletion…”
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Streptococcus pyogenes M49-16 Arginine Deiminase Disrupts Actin Cytoskeleton and Monolayer Confluence in a Culture of Endothelial Cells by Mammedova, J. T., Karaseva, A. B., Burova, L. A., Sokolov, A. V., Perepletchikova, D. A., Malashicheva, A. B., Starikova, E. A.

“…The actin cytoskeleton is involved in the regulation of the endothelial barrier. Arginine bioavailability is an important factor that determines actin…”
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A role of streptokinase in experimental post-streptococcal glomerulonephritis by Burova, L. A., Gavrilov, E. A., Pigarevsky, P. V., Totolian, Artem A.

“…Post-streptococcal glomerulonephritis (PSGN) refers to the sequela of the acute infection, caused by Streptococcus pyogenes (group A streptococcus, GAS). This…”
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Influence of streptococcal arginine deiminase on the leukocyte infiltration in murine air pouch model by Starikova, E. A., Kudryavtsev, I. V., Burova, L. A., Lebedeva, A. M., Mammedova, J. T., Freidlin, I. S.

“…Numerous pathogens express arginine deiminase, an enzyme that catalyzes the hydrolysis of L-arginine in a chain of biochemical reactions aimed at the synthesis…”
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Impact of IgG Fc-fragments on experimental glomerulonephritis induced by Streptococcus pyogenes strain binding various immunoglobulin classes by Burova, L. A., Pigarevsky, P. V., Snegova, V. A., Totolian, A. A.

“…The pathogenesis of poststreptococcal glomerulonephritis (PSGN), a major complication of acute infections caused by group A streptococci (GAS) remains unclear…”
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S. pyogenes M49-16 arginine deiminase inhibits proliferative activity of human peripheral blood lymphocytes by Starickova, E. A., Leveshko, T. A., Churakina, D. V., Kudryavtsev, I. V., Burova, L. A., Freidlin, I. S.

“…Arginine deiminase is one of three enzymes constituting the arginine deiminase system in bacteria. It was demonstrated that arginine deiminase exerts…”
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Myocardial tissue damage in rabbits injected with group A streptococci, types M1 and M22. Role of bacterial immunoglobulin G-binding surface proteins by BUROVA, L. A., NAGORNEV, V. A., PIGAREVSKY, P. V., GLADILINA, M. M., GAVRILOVA, E. A., SELIVERSTOVA, V. G., TOTOLIAN, A. A., THERN, A., SCHALÉN, C.

“…Acute rheumatic fever (ARF) and acute poststreptococcal glomerulonephritis (APSGN), two important sequelae of streptococcal throat or skin infections,…”
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THE ROLE OF ARGININE DEIMINASE FROM STREPTOCOCCUS PYOGENES IN INHIBITION MACROPHAGES NITROGEN MONOXIDE (NO) SYNTHESIS by Starikova, E. A., Sokolov, A. V., Burova, L. A., Golovin, A. S., Lebedeva, A. M., Vasilyev, V. B., Freidlin, I. S.

“…The protective role of macrophages closely related to the production of bactericidal molecules, in which nitrogen monoxide (NO) play an  important role…”
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EFFECT OF ARGININE DEIMINASE FROM STREPTOCOCCUS PYOGENES ON CYTOSKELETON STRUCTURE AND MIGRATION ACTIVITY OF HUMAN ENDOTHELIAL CELLS by Starikova, E. A., Mammedova, J. T., Burova, L. A., Sokolov, A. V., Vasilyev, V. B., Freidlin, I. S.

“…There is a growing body of data about the cytopathic effect of bacterial arginine deiminase on human endothelial cells, but the precise mechanisms of…”
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IMMUNOSUPPRESSIVE EFFECTS OF ARGININE DEIMINASE FROM STREPTOCOCCUS PYOGENES by Starikova, E. A., Sokolov, A. V., Burova, L. A., Freidlin, I. S.

“…Many pathogens use metabolic pathway of arginine for successful dissemination. Bacterial arginine deiminase hydrolyzes arginine to form one molecule of ammonia…”
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Nephritogenic activity of IgA-binding streptococcus pyogenes : An experimental model of IgA glomerulonephritis by Burova, L. A., Pigarevsky, P. V., Snegova, V. A., Duplik, N. V., Schalén, Claës, Totolian, Artem A.

“…The aim of present study was to arrange an experimental rabbit model for IgA-nephropathy. To this purpose, an approach was attempted which was previously…”
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Monocytes of human blood as a target of Streptococcus pyogenes components by Lebedeva, A M, Starikova, E A, Burova, L A, Freĭdlin, I S, Samoĭlova, K A

“…Study the effect of components of destroyed streptococci on human blood monocyte functions related to processes of trans-endothelial migration in vitro…”
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A ROLE OF ARGININE DEIMINASE FROM STREPTOCOCCUS PYOGENES M49-16 IN PROMOTING INFECTION AND INHIBITION OF ENDOTHELIAL CELL PROLIFERATION by Starikova, E. A., Karaseva, A. B., Burova, L. A., Suvorov, A. N., Sokolov, A. V., Vasilyev, V. B., Freidlin, I. S.

“…Arginine deiminase is a bacterial enzyme that hydrolyses arginine with citrulline and ammonia formation. In recent years, increasing evidence is reported about…”
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CHANGES IN MONOCYTE ADHESION TO ENDOTHELIAL CELLS UNDER THE INFLUENCE OF STREPTOCOCCUS PYOGENES COMPONENTS by Lebedeva, A. M., Starikova, E. A., Burova, L. A., Freidlin, I. S.

“…Adhesion to blood vessel endothelium is an important stage of leukocyte migration. This study was aimed for studying the effects of supernates from…”
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NEPHRITOGENIC ACTIVITY OF STREPTOCOCCUS PYOGENES emm1 AND emm12 GENOTYPES ISOLATED FROM PATIENTS AND ASYMPTOMATIC CARRIERS by Burova, L. A., Pigarevsky, P. V., Snegova, V. A., Kuleshevich, E. V., Zharkov, D. A., Schalen, C., Totolian, Artem A.

“…In this paper the nephritogenic activity of Streptococcus pyogenes genotype emm1 and emm12 clinical isolates from scarlet fever patients and healthy children…”
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Immunopathological acute poststreptococcal glomerulonephritis (AGN): analysis of development mechanisms by Totolian, A A, Burova, L A, Nagornev, V A, Pigarevskiĭ, P V

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REGULATORY MECHANISMS OF HUMAN MONOCYTIC THP-1 CELLS TRANSENDOTHELIAL MIGRATION INDUCED BY STREPTOCOCCUS PYOGENES COMPONENTS by Starikova, E. A., Lebedeva, A. M., Aktureeva, N. A., Burova, L. A., Freidlin, I. S.

“…Enhanced transendothelial migration of leukocytes during infection and inflammation occurs due to increased expression of ICAM-1 and VCAM-1 adherence molecules…”
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