Search Results - "Burns, Kathryn Elisa"

Molecular mechanisms of genetic variation and transcriptional regulation of CYP2C19 by Helsby, Nuala Ann, Burns, Kathryn Elisa

“…Inherited variation in the function of the drug metabolizing enzyme CYP2C19 was first observed 40 years ago. The SNP variants which underpin loss of CYP2C19…”
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The Concise Guide to PHARMACOLOGY 2023/24: Enzymes by Alexander, Stephen P. H., Fabbro, Doriano, Kelly, Eamonn, Mathie, Alistair A., Peters, John A., Veale, Emma L., Armstrong, Jane F., Faccenda, Elena, Harding, Simon D., Davies, Jamie A., Annett, Stephanie, Boison, Detlev, Burns, Kathryn Elisa, Dessauer, Carmen, Gertsch, Jurg, Helsby, Nuala Ann, Izzo, Angelo A., Ostrom, Rennolds, Papapetropoulos, Andreas, Pyne, Nigel J., Pyne, Susan, Robson, Tracy, Seifert, Roland, Stasch, Johannes‐Peter, Szabo, Csaba, Stelt, Mario, Vliet, Albert, Watts, Val, Wong, Szu Shen

“…The Concise Guide to PHARMACOLOGY 2023/24 is the sixth in this series of biennial publications. The Concise Guide provides concise overviews, mostly in tabular…”
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THE CONCISE GUIDE TO PHARMACOLOGY 2021/22: Enzymes by Alexander, Stephen PH, Fabbro, Doriano, Kelly, Eamonn, Mathie, Alistair, Peters, John A, Veale, Emma L, Armstrong, Jane F, Faccenda, Elena, Harding, Simon D, Pawson, Adam J, Southan, Christopher, Davies, Jamie A, Boison, Detlev, Burns, Kathryn Elisa, Dessauer, Carmen, Gertsch, Jürg, Helsby, Nuala Ann, Izzo, Angelo A., Koesling, Doris, Ostrom, Rennolds, Pyne, Nigel J., Pyne, Susan, Russwurm, Michael, Seifert, Roland, Stasch, Johannes‐Peter, Stelt, Mario, Vliet, Albert, Watts, Val, Wong, Szu Shen

“…The Concise Guide to PHARMACOLOGY 2021/22 is the fifth in this series of biennial publications. The Concise Guide provides concise overviews, mostly in tabular…”
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Intracellular activation of 4-hydroxycyclophosphamide into a DNA-alkylating agent in human leucocytes by Yong, Minghan, Burns, Kathryn Elisa, de Zoysa, Janak, Helsby, Nuala Ann

“…1.The conversion of the cyclophosphamide intermediate metabolite 4-hydroxycyclophosphamide (4-OHCP) to the final cytotoxic metabolite phosphoramide mustard…”
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Indirect regulation of CYP2C19 gene expression via DNA methylation by Burns, Kathryn Elisa, Shepherd, Phillip, Finlay, Graeme, Tingle, Malcolm Drummond, Helsby, Nuala Ann

“…1. Despite speculation that the CYP2C19 gene may contain CpG islands, there has been little direct assessment of the role for epigenetics in the regulation of…”
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The Concise Guide to PHARMACOLOGY 2021/22 by Alexander, Stephen P H, Fabbro, Doriano, Kelly, Eamonn, Mathie, Alistair, Peters, John A, Veale, Emma L, Armstrong, Jane F, Faccenda, Elena, Harding, Simon D, Pawson, Adam J, Southan, Christopher, Davies, Jamie A, Annett, Stephanie, Boison, Detlev, Burns, Kathryn Elisa, Dessauer, Carmen, Gertsch, Jürg, Helsby, Nuala Ann, Izzo, Angelo A, Koesling, Doris, Ostrom, Rennolds, Papapetropoulos, Andreas, Pyne, Nigel J, Pyne, Susan, Robson, Tracy, Russwurm, Michael, Seifert, Roland, Johannes‐Peter Stasch, Szabo, Csaba, van der Stelt, Mario, van der Vliet, Albert, Watts, Val, Szu Shen Wong

“…The Concise Guide to PHARMACOLOGY 2021/22 is the fifth in this series of biennial publications. The Concise Guide provides concise overviews, mostly in tabular…”
Get full text