Search Results - "Burns, H.Donald"

Human positron emission tomography studies of brain neurokinin 1 receptor occupancy by aprepitant by Bergström, Mats, Hargreaves, Richard J, Burns, H.Donald, Goldberg, Michael R, Sciberras, David, Reines, Scott A, Petty, Kevin J, Ögren, Mattias, Antoni, Gunnar, Långström, Bengt, Eskola, Olli, Scheinin, Mika, Solin, Olof, Majumdar, Anup K, Constanzer, Marvin L, Battisti, Wendy P, Bradstreet, Thomas E, Gargano, Cynthia, Hietala, Jarmo

“…Aprepitant is a highly selective substance P (neurokinin 1 [NK 1] receptor) antagonist that significantly improves the pharmacotherapy of acute and delayed…”
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Characterization of specific binding of [formula omitted]L-762,459, a selective α1A-adrenoceptor radioligand to rat and human tissues by O'Malley, Stacey S, Chen, Tsing B, Francis, Barbara E, Gibson, Raymond E, Burns, H.Donald, DiSalvo, Jerry, Bayne, Marvin L, Wetzel, John M, Nagarathnam, Dhanapalan, Marzabadi, Mohammad, Gluchowski, Charles, Chang, Raymond S.L

“…L-762,459…”
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A remote-controlled high pressure reactor for radiotracer synthesis with [ 11C]carbon monoxide by Hostetler, Eric D, Burns, H.Donald

“…[ 11C]Carbon monoxide is a versatile building block for the synthesis of PET radiotracers. However, the difficulty of trapping [ 11C]CO in a small solvent…”
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An in vitro assay for predicting successful imaging radiotracers by Patel, Shil, Hamill, Terence, Hostetler, Eric, Burns, H Donald, Gibson, Raymond E

“…To develop an in vitro binding assay able to predict whether a radiolabel is likely to be a useful clinical tracer for positron emission tomography (PET)…”
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Image-derived input function for [11C]flumazenil kinetic analysis in human brain by Sanabria-Bohórquez, Sandra M, Maes, Alex, Dupont, Patrick, Bormans, Guy, de Groot, Tjibbe, Coimbra, Alexandre, Eng, WaiSi, Laethem, Tine, De Lepeleire, Inge, Gambale, Jay, Vega, Jose M, Burns, H Donald

“…We describe a method for analysis of [11C]flumazenil data using an input curve directly derived from the positron emission tomography (PET) images. The shape…”
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Radioiodinated endothelin-1: a radiotracer for imaging endothelin receptor distribution and occupancy by Gibson, Raymond E, Fioravanti, Christine, Francis, Barbara, Burns, H.Donald

“…Endothelin (ET) is one of the most potent vasoconstrictors known. Recently, ET has been implicated in various diseases, e.g., acute renal failure and…”
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Receptor binding radiotracers for the angiotensin II receptor: radioiodinated [Sar1, Ile8]Angiotensin II by Gibson, R E, Beauchamp, H T, Fioravanti, C, Brenner, N, Burns, H D

“…The potential for imaging the angiotensin II receptor was evaluated using the radioiodinated peptide antagonist [125I][Sar1, Ile8)angiotensin II. The…”
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Chapter 26. PET ligands for assessing receptor occupancy in vivo by Burns, H.Donald, Hamill, Terence G., Eng, Wai-si, Hargreaves, Richard

“…Interest in using PET for assessing receptor occupancy in vivo continues to increase and development new PET radioligands remains an active area of research…”
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(+)-3-[123I]Iodo-MK-801: synthesis and characterization of binding to the N-methyl-D-aspartate receptor complex by Ransom, R W, Eng, W S, Burns, H D, Gibson, R E, Solomon, H F

“…Synthetic methods have been established for preparing high specific activity (+)-3-[123I]Iodo-MK-801 in high radiochemical yield. The binding of the…”
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In vivo binding and autoradiographic imaging of (+)-3-[125I]Iodo-MK-801 to the NMDA receptor-channel complex in rat brain by Gibson, E G, Burns, H D, Thorpe, H H, Eng, W S, Ransom, R, Solomon, H

“…Radioiodinated (+)-3-Iodo-MK-801 is a high affinity radioligand for the N-methyl-D-aspartate (NMDA) receptor-channel complex. We have demonstrated in vivo…”
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A radioiodinated quinoline DNA complex as a potential melanoma imaging agent by Heindel, N D, Emrich, J G, Burns, H D, Dannals, R, Schneider, R

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