Search Results - "Burnouf, Catherine"

Recent advances in PDE4 inhibitors as immunoregulators and anti-inflammatory drugs by Burnouf, Catherine, Pruniaux, Marie-Pierre

“…The phosphodiesterases (PDEs) are responsible for the hydrolysis of intracellular cyclic adenosine and guanosine monophosphate (cAMP and cGMP, respectively)…”
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Relationship between phosphodiesterase type 4 inhibition and anti-inflammatory activity of CI-1044 in rat airways by Pruniaux, Marie-Pierre, Lagente, Vincent, Ouaged, Malika, Bertin, Bernadette, Moreau, François, Julien-Larose, Christine, Rocher, Marie-Noelle, Leportier, Christelle, Martin, Brigitte, Bouget, Anita, Dubuit, Jean-Pierre, Burnouf, Catherine, Doherty, Annette M., Bertrand, Claude P.

“…The anti‐inflammatory effects of CI‐1044 and of the other selective PDE4 inhibitors rolipram and cilomilast were investigated in Brown‐Norway (BN) rats,…”
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Synthesis, Structure−Activity Relationships, and Pharmacological Profile of 9-Amino-4-oxo-1-phenyl-3,4,6,7-tetrahydro[1,4]diazepino[6,7,1-h i]indoles:  Discovery of Potent, Selective Phosphodiesterase Type 4 Inhibitors by Burnouf, Catherine, Auclair, Eric, Avenel, Nadine, Bertin, Bernadette, Bigot, Christèle, Calvet, Alain, Chan, Kam, Durand, Corinne, Fasquelle, Veronique, Féru, Frédéric, Gilbertsen, Richard, Jacobelli, Henry, Kebsi, Adel, Lallier, Emmanuelle, Maignel, Jacquie, Martin, Brigitte, Milano, Stéphane, Ouagued, Malika, Pascal, Yves, Pruniaux, Marie-Pierre, Puaud, Jocelyne, Rocher, Marie-Noëlle, Terrasse, Christophe, Wrigglesworth, Roger, Doherty, Annette M

“…The synthesis, structure−activity relationships, and biological properties of a novel series of potent and selective phosphodiesterase type 4 (PDE4) inhibitors…”
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