Open Retromuscular Mesh Repair of Complex Incisional Hernia: Predictors of Wound Events and Recurrence

Background Mesh repair of incisional hernias has been consistently shown to diminish recurrence rates after repair, with an increased risk of infectious complications. We present a consecutive series of elective, retrorectus mesh repairs of the abdominal wall and attempt to determine predictors of w...

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Published in:	Journal of the American College of Surgeons Vol. 220; no. 4; pp. 606 - 613
Main Authors:	Cobb, William S., MD, FACS, Warren, Jeremy A., MD, Ewing, Joseph A., BS, Burnikel, Alex, Merchant, Miller, Carbonell, Alfredo M., DO, FACS
Format:	Journal Article
Language:	English
Published:	United States Elsevier Inc 01-04-2015
Subjects:	Abdominal Wall - surgery Adult Aged Aged, 80 and over Female Follow-Up Studies Hernia, Ventral - surgery Herniorrhaphy - methods Humans Incidence Male Middle Aged Prognosis Recurrence Retrospective Studies South Carolina - epidemiology Surgery Surgical Mesh Surgical Wound Infection - epidemiology Young Adult South Carolina SSI OR surgical site occurrence odds ratio SSO surgical site infection
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Summary:	Background Mesh repair of incisional hernias has been consistently shown to diminish recurrence rates after repair, with an increased risk of infectious complications. We present a consecutive series of elective, retrorectus mesh repairs of the abdominal wall and attempt to determine predictors of wound events and recurrence. Study Design A retrospective review was performed to include elective, retromuscular mesh repairs of complex incisional hernias from August 2006 to August 2013. Demographics, operative details, and postoperative events including wound events, surgical site infections (SSI), and recurrences were recorded. Results Over the 7-year period, 255 retromuscular mesh repairs of midline incisional defects were performed. Median age of the patients was 58 years, with an average BMI of 32.2 kg/m2 . Average size of the fascial defect was 181.4 cm2 , with recurrent defects making up 48% of repairs. Wound events occurred in 37.7% of cases; SSIs occurred in 19.6% of cases. Recurrence rate was 16.9%, with mean time to recurrence of 19.2 months. With respect to mesh type, recurrences were 16.2% with synthetic, 17.1% for bioabsorbable, and 25% for biologic mesh. When evaluating polypropylene meshes, recurrence was more likely with lightweight mesh (22.9%) vs midweight mesh (10.6%) (p = 0.045). Predictors of SSI included history of mesh infection (odds ratio [OR] 4.8, 95% CI 1.9 to 12.1; p < 0.001) and recurrent repairs (OR 2.5, 95% CI 1.1 to 5.8; p < 0.05). The only predictor of recurrence was the presence of an SSI (OR 3.1, 95% CI 1.5 to 6.3; p < 0.01). Conclusions Wound events are common after open mesh repairs of complex incisional hernias. Previous mesh infections and recurrent repairs increase the likelihood of an SSI, which significantly increases the risk of recurrence. Recurrences after retrorectus mesh repairs are significantly higher with lightweight compared with mid-weight meshes.
Bibliography:	ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23
ISSN:	1072-7515 1879-1190
DOI:	10.1016/j.jamcollsurg.2014.12.055