Search Results - "Burnham, Daniel R"
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Bioconjugation of Ultrabright Semiconducting Polymer Dots for Specific Cellular Targeting
Published in Journal of the American Chemical Society (03-11-2010)“…Semiconducting polymer dots (Pdots) represent a new class of ultrabright fluorescent probes for biological imaging. They exhibit several important…”
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2
The mechanism of DNA unwinding by the eukaryotic replicative helicase
Published in Nature communications (14-05-2019)“…Accurate DNA replication is tightly regulated in eukaryotes to ensure genome stability during cell division and is performed by the multi-protein replisome. At…”
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3
Design of Highly Emissive Polymer Dot Bioconjugates for In Vivo Tumor Targeting
Published in Angewandte Chemie International Edition (04-04-2011)“…Lighting up brain tumors: Highly fluorescent nanodots that consist of semiconducting polymer blends were attached to the peptide ligand chlorotoxin. The…”
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4
Ultrabright and Bioorthogonal Labeling of Cellular Targets Using Semiconducting Polymer Dots and Click Chemistry
Published in Angewandte Chemie (International ed.) (03-12-2010)“…All aboard! A facile conjugation method allows covalent linking of functional molecules to semiconducting polymer dots for bioorthogonal labeling of cellular…”
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5
The bacterial replication origin BUS promotes nucleobase capture
Published in Nature communications (14-12-2023)“…Genome duplication is essential for the proliferation of cellular life and this process is generally initiated by dedicated replication proteins at chromosome…”
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Magnetic forces and DNA mechanics in multiplexed magnetic tweezers
Published in PloS one (03-08-2012)“…Magnetic tweezers (MT) are a powerful tool for the study of DNA-enzyme interactions. Both the magnet-based manipulation and the camera-based detection used in…”
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7
Retrieval of the complex refractive index of aerosol droplets from optical tweezers measurements
Published in Physical chemistry chemical physics : PCCP (01-01-2012)“…The cavity enhanced Raman scattering spectrum recorded from an aerosol droplet provides a unique fingerprint of droplet radius and refractive index, assuming…”
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8
Skewed brownian fluctuations in single-molecule magnetic tweezers
Published in PloS one (29-09-2014)“…Measurements in magnetic tweezers rely upon precise determination of the position of a magnetic microsphere. Fluctuations in the position due to Brownian…”
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Editorial for the Special Issue on Optical Trapping and Manipulation: From Fundamentals to Applications
Published in Micromachines (Basel) (15-04-2020)“…This Special Issue of is devoted to optical trapping, and the enormous range of uses the method has found in the decades since its first demonstration [...]…”
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10
Copper-free click chemistry for attachment of biomolecules in magnetic tweezers
Published in BMC biophysics (25-09-2015)“…Single-molecule techniques have proven to be an excellent approach for quantitatively studying DNA-protein interactions at the single-molecule level. In…”
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11
Three-dimensional super-resolution fluorescence imaging of DNA
Published in Scientific reports (27-07-2020)“…Recent advances in fluorescence super-resolution microscopy are providing important insights into details of cellular structures. To acquire three dimensional…”
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12
Annealing helicase HARP closes RPA-stabilized DNA bubbles non-processively
Published in Nucleic acids research (05-05-2017)“…We investigate the mechanistic nature of the Snf2 family protein HARP, mutations of which are responsible for Schimke immuno-osseous dysplasia. Using a…”
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13
Self-Digitization of Samples into a High-Density Microfluidic Bottom-Well Array
Published in Analytical chemistry (Washington) (05-11-2013)“…This paper describes a sample digitization method that generates tens of thousands of nanoliter-sized droplets in a high-density array in a matter of minutes…”
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14
Validation of the plasmid study to relate DNA damaging effects of radionuclides to those from external beam radiotherapy
Published in Nuclear medicine and biology (01-09-2021)“…The biological consequences of absorbed radiation doses are ill-defined for radiopharmaceuticals, unlike for external beam radiotherapy (EBRT). A reliable…”
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15
Toward optical-tweezers-based force microscopy for airborne microparticles
Published in Applied optics. Optical technology and biomedical optics (20-12-2014)“…Optical tweezers have found widespread application in biological and colloidal physics for the measurement of pN forces over nanometer to micrometer length…”
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16
Thermocapillary manipulation of droplets using holographic beam shaping: Microfluidic pin ball
Published in Applied physics letters (21-07-2008)“…We demonstrate that holographically generated optical patterns offer greater flexibility for the thermocapillary control of water droplets than Gaussian spots;…”
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17
Spectroscopic characterisation and manipulation of arrays of sub-picolitre aerosol droplets
Published in Lab on a chip (21-02-2009)“…Arrays of optically tweezed aerosol droplets, each of sub-picolitre volume, are manipulated by holographic optical tweezers and characterised by cavity…”
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18
Single aerosol trapping with an annular beam: improved particle localisation
Published in Physical chemistry chemical physics : PCCP (05-12-2012)“…In this paper we explore the trapping of aerosol droplets using an annular beam, formed by blocking the central portion of a Gaussian beam, and quantify the…”
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Mixing via thermocapillary generation of flow patterns inside a microfluidic drop
Published in New journal of physics (31-07-2009)“…The heating produced by a focused laser has been shown to provide a range of manipulation tools on droplets in microfluidic situations, through the generation…”
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Ultrabright and Bioorthogonal Labeling of Cellular Targets Using Semiconducting Polymer Dots and Click Chemistry
Published in Angewandte Chemie (03-12-2010)“…Leuchtende Halbleiterpolymerpunkte mit kovalent angebundenen funktionellen Molekülen eignen sich für die bioorthogonale Markierung von Zellbestandteilen. Das…”
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