Search Results - "Burnell, John E."
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Cetylpyridinium chloride (CPC) reduces zebrafish mortality from influenza infection: Super-resolution microscopy reveals CPC interference with multiple protein interactions with phosphatidylinositol 4,5-bisphosphate in immune function
Published in Toxicology and applied pharmacology (01-04-2022)“…The COVID-19 pandemic raises significance for a potential influenza therapeutic compound, cetylpyridinium chloride (CPC), which has been extensively used in…”
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Pharmaceutical agent cetylpyridinium chloride inhibits immune mast cell function by interfering with calcium mobilization
Published in Food and chemical toxicology (01-09-2023)“…Cetylpyridinium chloride (CPC) is an antimicrobial used in numerous personal care and janitorial products and food for human consumption at millimolar…”
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Antimicrobial cetylpyridinium chloride causes functional inhibition of mitochondria as potently as canonical mitotoxicants, nanostructural disruption of mitochondria, and mitochondrial Ca 2+ efflux in living rodent and primary human cells
Published in Food and chemical toxicology (01-04-2024)“…People are exposed to high concentrations of antibacterial agent cetylpyridinium chloride (CPC) via food and personal care products, despite little published…”
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Antimicrobial cetylpyridinium chloride causes functional inhibition of mitochondria as potently as canonical mitotoxicants, nanostructural disruption of mitochondria, and mitochondrial Ca2+ efflux in living rodent and primary human cells
Published in Food and chemical toxicology (01-04-2024)“…People are exposed to high concentrations of antibacterial agent cetylpyridinium chloride (CPC) via food and personal care products, despite little published…”
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Journal Article -
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Triclosan disrupts immune cell function by depressing Ca2+ influx following acidification of the cytoplasm
Published in Toxicology and applied pharmacology (15-10-2020)“…Triclosan (TCS) is an antimicrobial agent that was effectively banned by the FDA from hand soaps in 2016, hospital soaps in 2017, and hand sanitizers in 2019;…”
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Triclosan disrupts immune cell function by depressing Ca 2+ influx following acidification of the cytoplasm
Published in Toxicology and applied pharmacology (15-10-2020)“…Triclosan (TCS) is an antimicrobial agent that was effectively banned by the FDA from hand soaps in 2016, hospital soaps in 2017, and hand sanitizers in 2019;…”
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Journal Article