Search Results - "Burmeister, Melissa"
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Exendin-4 attenuates high glucose-induced cardiomyocyte apoptosis via inhibition of endoplasmic reticulum stress and activation of SERCA2a
Published in American Journal of Physiology: Cell Physiology (15-03-2013)“…Hyperglycemia-induced cardiomyocyte apoptosis contributes to diabetic cardiomyopathy. Glucagon-like peptide-1 (Glp1) receptor (Glp1r) agonists improve cardiac…”
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2
Cellular Sites and Mechanisms Linking Reduction of Dipeptidyl Peptidase-4 Activity to Control of Incretin Hormone Action and Glucose Homeostasis
Published in Cell metabolism (10-01-2017)“…Pharmacological inhibition of the dipeptidyl peptidase-4 (DPP4) enzyme potentiates incretin action and is widely used to treat type 2 diabetes. Nevertheless,…”
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3
Differential effects of cannabis constituents on schizophrenia-related psychosis: a rationale for incorporating cannabidiol into a schizophrenia therapeutic regimen
Published in Frontiers in psychiatry (23-04-2024)“…Schizophrenia is a serious mental health disorder that confers one of the highest mortality rates of all psychiatric illnesses. Although the disorder's…”
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The Hypothalamic Glucagon-Like Peptide 1 Receptor Is Sufficient but Not Necessary for the Regulation of Energy Balance and Glucose Homeostasis in Mice
Published in Diabetes (New York, N.Y.) (01-02-2017)“…Pharmacological activation of the hypothalamic glucagon-like peptide 1 (GLP-1) receptor (GLP-1R) promotes weight loss and improves glucose tolerance. This…”
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5
Real-world community hospital hyperglycemia management in noncritically ill, type 2 diabetic patients: a comparison between basal-bolus insulin and correctional insulin
Published in Journal of pharmacy & pharmaceutical sciences (2024)“…This study evaluated the safety and efficacy of two insulin regimens for inpatient hyperglycemia management: combination short-plus long-acting insulin…”
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The pharmacist’s role in reducing infusion-related phlebitis
Published in American journal of health-system pharmacy (21-07-2023)“…Abstract Purpose Pharmacists oversee parenteral drug preparation and administration in hospitals, clinics, infusion centers, and home infusion settings…”
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7
Evidence for proton-pump inhibitor (PPI)-associated dysbiosis in metabolically unhealthy obesity
Published in Frontiers in endocrinology (Lausanne) (15-06-2023)“…Obesity adversely impacts millions of American adults by predisposing them to significant health risks and further complications. Obesity is differentiated…”
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Central glucagon-like peptide 1 receptor-induced anorexia requires glucose metabolism-mediated suppression of AMPK and is impaired by central fructose
Published in American journal of physiology: endocrinology and metabolism (01-04-2013)“…Glucagon-like peptide-1 (GLP-1) suppresses food intake via activation of a central (i.e., brain) GLP-1 receptor (GLP-1R). Central AMP-activated protein kinase…”
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9
Acute activation of central GLP-1 receptors enhances hepatic insulin action and insulin secretion in high-fat-fed, insulin resistant mice
Published in American journal of physiology: endocrinology and metabolism (01-02-2012)“…Glucagon-like peptide-1 (GLP-1) receptor knockout (Glp1r(-/-)) mice exhibit impaired hepatic insulin action. High fat (HF)-fed Glp1r(-/-) mice exhibit…”
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The glucagon-like peptide-1 receptor in the ventromedial hypothalamus reduces short-term food intake in male mice by regulating nutrient sensor activity
Published in American journal of physiology: endocrinology and metabolism (01-12-2017)“…Pharmacological activation of the glucagon-like peptide-1 receptor (GLP-1R) in the ventromedial hypothalamus (VMH) reduces food intake. Here, we assessed…”
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11
Targeted inhibition of complement activation prevents features of preeclampsia in mice
Published in Kidney international (01-02-2011)“…Preeclampsia is a major cause of maternal and neonatal morbidity and mortality. In mouse models, complement activation in the placenta is associated with…”
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Glucagon-Like Peptide-1 Receptor Knockout Mice Are Protected from High-Fat Diet-Induced Insulin Resistance
Published in Endocrinology (Philadelphia) (01-10-2010)“…Glucagon-like peptide-1 augments nutrient-stimulated insulin secretion. Chow-fed mice lacking the glucagon-like peptide-1 receptor (Glp1r) exhibit enhanced…”
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13
Silencing Nox4 in the Paraventricular Nucleus Improves Myocardial Infarction–Induced Cardiac Dysfunction by Attenuating Sympathoexcitation and Periinfarct Apoptosis
Published in Circulation research (11-06-2010)“…RATIONALE:Myocardial infarction (MI)-induced heart failure is characterized by central nervous system–driven sympathoexcitation and deteriorating cardiac…”
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14
Genetic Silencing of Nox2 and Nox4 Reveals Differential Roles of These NADPH Oxidase Homologues in the Vasopressor and Dipsogenic Effects of Brain Angiotensin II
Published in Hypertension (Dallas, Tex. 1979) (01-11-2009)“…The renin-angiotensin system exerts a tremendous influence over fluid balance and arterial pressure. Angiotensin II (Ang-II), the effector peptide of the…”
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15
Cardiovascular Risk Reduction: A Pharmacotherapeutic Update for Antiplatelet Medications
Published in Critical care nursing clinics of North America (01-03-2019)“…This update presents evidence for new antiplatelet therapies including modified P2Y inhibitors and a new class of thromboxane antagonists. Discussed are…”
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Angiotensin II–Dependent Hypertension Requires Cyclooxygenase 1–Derived Prostaglandin E2 and EP1 Receptor Signaling in the Subfornical Organ of the Brain
Published in Hypertension (Dallas, Tex. 1979) (01-04-2012)“…Cyclooxygenase (COX)-derived prostanoids have long been implicated in blood pressure (BP) regulation. Recently prostaglandin E2 (PGE2) and its receptor EP1…”
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17
Exendin-4 improves cardiac function in mice overexpressing monocyte chemoattractant protein-1 in cardiomyocytes
Published in Journal of molecular and cellular cardiology (01-11-2014)“…Abstract The incretin hormone glucagon-like peptide-1 (Glp1) is cardioprotective in models of ischemia-reperfusion injury, myocardial infarction and…”
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In Vivo Bioluminescence Imaging Reveals Redox-Regulated Activator Protein-1 Activation in Paraventricular Nucleus of Mice With Renovascular Hypertension
Published in Hypertension (Dallas, Tex. 1979) (01-02-2011)“…Renovascular hypertension in mice is characterized by an elevation in hypothalamic angiotensin II levels. The paraventricular nucleus (PVN) is a major…”
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Cardiovascular responses to peripheral chemoreflex activation and comparison of different methods to evaluate baroreflex gain in conscious mice using telemetry
Published in American journal of physiology. Regulatory, integrative and comparative physiology (01-10-2008)“…Peripheral chemoreceptors located in the carotid bodies are the primary sensors of systemic hypoxia. Although the pattern of responses elicited by peripheral…”
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Centrally administered nociceptin/orphanin FQ (N/OFQ) evokes bradycardia, hypotension, and diuresis in mice via activation of central N/OFQ peptide receptors
Published in The Journal of pharmacology and experimental therapeutics (01-07-2007)“…The present studies examined the cardiovascular and renal responses produced by activation of central nociceptin/orphanin FQ (N/OFQ) peptide (NOP) receptors in…”
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