Search Results - "Burlot, Chloé"
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Procaspase-Activating Compound-1 Synergizes with TRAIL to Induce Apoptosis in Established Granulosa Cell Tumor Cell Line (KGN) and Explanted Patient Granulosa Cell Tumor Cells In Vitro
Published in International journal of molecular sciences (29-04-2021)“…Granulosa cell tumors (GCT) constitute only ~5% of ovarian neoplasms yet have significant consequences, as up to 80% of women with recurrent GCT will die of…”
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Journal Article -
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Improving olaparib exposure to optimize adverse effects management
Published in Therapeutic advances in medical oncology (01-01-2024)“…Olaparib is an inhibitor of the human poly-(ADP-ribose)-polymerase enzymes (PARP1/2) needed to repair single-strand DNA breaks. It is used in breast, ovarian,…”
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Journal Article -
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Establishing combination PAC‐1 and TRAIL regimens for treating ovarian cancer based on patient‐specific pharmacokinetic profiles using in silico clinical trials
Published in Computational and systems oncology (01-06-2022)“…Ovarian cancer is commonly diagnosed in its late stages, and new treatment modalities are needed to improve patient outcomes and survival. We have recently…”
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Journal Article