Search Results - "Burlingham, William J."
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Extracellular matrix scaffold and hydrogel derived from decellularized and delipidized human pancreas
Published in Scientific reports (11-07-2018)“…Extracellular matrix (ECM) plays an important developmental role by regulating cell behaviour through structural and biochemical stimulation. Tissue-specific…”
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Milk and the "Grandmother Effect"- a new contribution to the legacy of Ray Owen
Published in Haematologica (Roma) (01-02-2019)Get full text
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Functional characterization of human pluripotent stem cell-derived arterial endothelial cells
Published in Proceedings of the National Academy of Sciences - PNAS (25-07-2017)“…Here, we report the derivation of arterial endothelial cells from human pluripotent stem cells that exhibit arterial-specific functions in vitro and in vivo…”
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A New Model of Epstein-Barr Virus Infection Reveals an Important Role for Early Lytic Viral Protein Expression in the Development of Lymphomas
Published in Journal of Virology (01-01-2011)“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Modification of host dendritic cells by microchimerism-derived extracellular vesicles generates split tolerance
Published in Proceedings of the National Academy of Sciences - PNAS (31-01-2017)“…Maternal microchimerism (MMc) has been associated with development of allospecific transplant tolerance, antitumor immunity, and cross-generational…”
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An Epstein-Barr Virus (EBV) Mutant with Enhanced BZLF1 Expression Causes Lymphomas with Abortive Lytic EBV Infection in a Humanized Mouse Model
Published in Journal of Virology (01-08-2012)“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Epigenetic Priming of Human Pluripotent Stem Cell‐Derived Cardiac Progenitor Cells Accelerates Cardiomyocyte Maturation
Published in Stem cells (Dayton, Ohio) (01-07-2019)“…Human pluripotent stem cell‐derived cardiomyocytes (hPSC‐CMs) exhibit a fetal phenotype that limits in vitro and therapeutic applications. Strategies to…”
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Bioengineered vocal fold mucosa for voice restoration
Published in Science translational medicine (18-11-2015)“…Patients with voice impairment caused by advanced vocal fold (VF) fibrosis or tissue loss have few treatment options. A transplantable, bioengineered VF mucosa…”
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Infectious Tolerance as Seen With 2020 Vision: The Role of IL-35 and Extracellular Vesicles
Published in Frontiers in immunology (26-08-2020)“…Originally identified as lymphocyte regulation of fellow lymphocytes, our understanding of infectious tolerance has undergone significant evolutions in…”
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A Humanized Mouse Model Generated Using Surplus Neonatal Tissue
Published in Stem cell reports (10-04-2018)“…Here, we describe the NeoThy humanized mouse model created using non-fetal human tissue sources, cryopreserved neonatal thymus and umbilical cord blood…”
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Naturally acquired tolerance and sensitization to minor histocompatibility antigens in healthy family members
Published in Blood (10-09-2009)“…Bidirectional cell transfer during pregnancy frequently leads to postpartum persistence of allogeneic cells and alloimmune responses in both the mother and in…”
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A Human Pluripotent Stem Cell-Based Screen for Smooth Muscle Cell Differentiation and Maturation Identifies Inhibitors of Intimal Hyperplasia
Published in Stem cell reports (11-06-2019)“…Contractile to synthetic phenotypic switching of smooth muscle cells (SMCs) contributes to stenosis in vascular disease and vascular transplants. To generate…”
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Treg-Cell-Derived IL-35-Coated Extracellular Vesicles Promote Infectious Tolerance
Published in Cell reports (Cambridge) (28-01-2020)“…Interleukin-35 (IL-35) is an immunosuppressive cytokine composed of Epstein-Barr-virus-induced protein 3 (Ebi3) and IL-12α chain (p35) subunits, yet the forms…”
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HY immune tolerance is common in women without male offspring
Published in PloS one (19-03-2014)“…Sex difference is an established risk factor for hematopoietic stem cell transplantation (HSCT)-related complications like graft versus host disease (GVHD)…”
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Microchimerism in cord blood: Mother as anticancer drug
Published in Proceedings of the National Academy of Sciences - PNAS (14-02-2012)Get full text
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Anti-Type V Collagen Humoral Immunity in Lung Transplant Primary Graft Dysfunction
Published in The Journal of immunology (1950) (15-10-2008)“…Primary graft dysfunction (PGD) is a major complication following lung transplantation. We reported that anti-type V collagen (col(V)) T cell immunity was…”
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Extracellular Vesicle–associated GARP/TGFβ:LAP Mediates “Infectious” Allo-tolerance
Published in Transplantation direct (01-06-2023)“…Here we test the hypothesis that, like CD81-associated "latent" IL35, the transforming growth factor (TGF)β:latency-associated peptide (LAP)/glycoprotein A…”
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Epitope analysis of the collagen type V-specific T cell response in lung transplantation reveals an HLA-DRB115 bias in both recipient and donor
Published in PloS one (12-11-2013)“…IL-17-dependent cellular immune responses to the α1 chain of collagen type V are associated with development of bronchiolitis obliterans syndrome after lung…”
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Extracellular vesicles in fetal-maternal immune tolerance
Published in Biomedical journal (01-10-2024)“…Two key problems of allo-tolerance during fetal-maternal co-existence are: 1) it's focus must be local, allowing the mother's continued peripheral immune…”
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Donor HLA−DR Drives the Development of De Novo Autoimmunity Following Lung and Heart Transplantation
Published in Transplantation direct (01-10-2020)“…Individuals harbor preexisting HLA-DR/DQ-restricted responses to collagen type V (ColV) mediated by Th17 cells under Treg control, both specific to peptides…”
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