Search Results - "Burlingame, R. W."

Anti-hydroxy-3-methylglutaryl-coenzyme A reductase (anti-HMGCR) antibody in necrotizing myopathy: treatment outcomes, cancer risk, and role of autoantibody level by Aggarwal, R, Moghadam-Kia, S, Lacomis, D, Malik, A, Qi, Z, Koontz, D, Burlingame, RW, Oddis, CV

“…Objective: To evaluate clinical associations of anti-hydroxy-3-methylglutaryl-coenzyme A reductase (anti-HMGCR) antibody (Ab) and statin exposure in…”
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Anti-C1q antibodies have higher correlation with flares of lupus nephritis than other serum markers by Akhter, E, Burlingame, RW, Seaman, AL, Magder, L, Petri, M

“…Objective. Autoantibodies are important in the diagnosis and classification of systemic lupus erythematosus (SLE), but whether they correlate with changes in…”
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Anti-RNA polymerase III antibodies in patients with systemic sclerosis detected by indirect immunofluorescence and ELISA by Parker, J. C., Burlingame, R. W., Webb, T. T., Bunn, C. C.

“…Objectives. To evaluate the analytical performance of an ELISA for the detection of anti-RNA polymerase III antibody (ARA) and to assess IIF as a method for…”
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Anti-chromatin antibodies in systemic lupus erythematosus: a useful marker for lupus nephropathy by Cervera, R, Viñas, O, Ramos-Casals, M, Font, J, García-Carrasco, M, Sisó, A, Ramírez, F, Machuca, Y, Vives, J, Ingelmo, M, Burlingame, R W

“…Background: Anti-chromatin antibodies have recently been described in patients with systemic lupus erythematosus (SLE) and it has been suggested that their…”
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Genesis and evolution of antichromatin autoantibodies in murine lupus implicates T-dependent immunization with self antigen by BURLINGAME, R. W, RUBIN, R. L, BALDERAS, R. S, THEOFILOPOULOS, A. N

“…Autoantibodies reacting with chromatin and its components, histones and DNA, are characteristic of the human autoimmune disease SLE and drug-induced lupus, but…”
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Coexistence of anti-RNA polymerase III and anti-U1RNP antibodies in patients with systemic lupus erythematosus: two cases without features of scleroderma by Satoh, M, Vazquez-Del Mercado, M, Krzyszczak, ME, Li, Y, Ceribelli, A, Burlingame, RW, Webb, TT, Sobel, ES, Reeves, WH, Chan, EKL

“…Anti-RNA polymerase III (RNAP III) antibodies are highly specific for scleroderma (SSc) and associated with diffuse SSc and renal crisis. Coexistence of…”
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The central role of chromatin in autoimmune responses to histones and DNA in systemic lupus erythematosus by Burlingame, R W, Boey, M L, Starkebaum, G, Rubin, R L

“…To gain insight into the mechanisms of autoantibody induction, sera from 40 patients with systemic lupus erythematosus (SLE) were tested by ELISAs for antibody…”
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Lupus Susceptibility Loci in New Zealand Mice by Kono, Dwight H., Burlingame, Rufus W., Owens, Dan G., Kuramochi, Akiko, Balderas, Robert S., Balomenos, Dimitrios, Theofilopoulos, Argyrios N.

“…Susceptibility to systemic lupus erythematosus has been unequivocally established to be an inherited trait, but the exact genes and how they confer…”
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The Nucleosomal Core Histone Octamer at 3.1⚬A Resolution: A Tripartite Protein Assembly and a Left-Handed Superhelix by Arents, Gina, Burlingame, Rufus W., Wang, Bi-Cheng, Love, Warner E., Moudrianakis, Evangelos N.

“…The structure of the octameric histone core of the nucleosome has been determined by x-ray crystallography to a resolution of 3.1 Å. The histone octamer is a…”
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Anti-Chromatin (Anti-Nucleosome) Antibodies by Gómez-Puerta, JA, Burlingame, RW, Cervera, R

“…Chromatin is the native complex of histones and DNA found in the cell nucleus of eukaryotes. The fundamental subunit of chromatin is the nucleosome, which is…”
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C-reactive protein binds to Fc gamma RI in transfected COS cells by Marnell, LL, Mold, C, Volzer, MA, Burlingame, RW, Du Clos, TW

“…C-Reactive protein (CRP) is an acute phase serum protein in man that binds to certain bacterial polysaccharides and to components exposed on damaged cells. CRP…”
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Subnucleosome structures as substrates in enzyme-linked immunosorbent assays by Burlingame, R W, Rubin, R L

“…Histone preparations preserving the tertiary and quaternary structure of histone-histone complexes and histone-DNA complexes, as well as individual histones,…”
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Anti-PM/Scl-100 and anti-RNA-polymerase III antibodies in scleroderma by Maes, L., Blockmans, D., Verschueren, P., Westhovens, R., Op De Beéck, K., Vermeersch, P., Van den Bergh, K., Burlingame, R.W., Mahler, M., Bossuyt, X.

“…Systemic sclerosis (SSc) is a rare autoimmune disease characterized by the presence of various autoantibodies, including anti-centromere, anti-topoisomerase…”
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Anti-CCP antibodies have more diagnostic impact than rheumatoid factor (RF) in a population tested for RF by Silveira, I G, Burlingame, R W, von Mühlen, C A, Bender, A L, Staub, H L

“…To compare the diagnostic powers of rheumatoid factor (RF) and anti-cyclic citrullinated peptide (CCP) in a population selected for its high statistical…”
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Autoantibodies associated with lupus induced by diverse drugs target a similar epitope in the (H2A-H2B)-DNA complex by RUBIN, R. L, BELL, S. A, BURLINGAME, R. W

“…IgG reactivity with the (H2A-H2B)-DNA complex, a subunit of the nucleosome, has been detected in many patients with lupus induced by procainamide and…”
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Antihistone antibodies in systemic lupus erythematosus: assay dependency and effects of ubiquitination and serum DNA by Suzuki, T, Burlingame, R W, Casiano, C A, Boey, M L, Rubin, R L

“…Antihistone antibodies occur in systemic lupus erythematosus (SLE) but there are many discrepancies in their reported prevalence, isotype, specificity and…”
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The clinical utility of antihistone antibodies. Autoantibodies reactive with chromatin in systemic lupus erythematosus and drug-induced lupus by Burlingame, R W

“…Autoantibodies reactive with denatured histones and with epitopes requiring the native histone-DNA structure in chromatin have been measured by many…”
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Drug-induced autoimmunity: a disorder at the interface between metabolism and immunity by Rubin, R L, Burlingame, R W

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Drug-induced anti-histone autoantibodies display two patterns of reactivity with substructures of chromatin by BURLINGAME, R. W, RUBIN, R. L

“…Increasing evidence suggests that autoantibodies in the rheumatic diseases are a consequence of immune selection by self-material, but the nature of the in…”
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Crystallographic Structure of the Octameric Histone Core of the Nucleosome at a Resolution of 3.3 Å by Burlingame, Rufus W., Love, Warner E., Bi-Chen Wang Ron Hamlin, Xuong, Nguyen-Huu, Moudrianakis, Evangelos N.

“…The structure of the (H2A-H2B-H3-H4)$_{2}$ histone octamer has been determined by means of x-ray crystallographic techniques at a resolution of 3.3 angstroms…”
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