Search Results - "Burleigh, Angela"
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Granzyme B inhibition reduces disease severity in autoimmune blistering diseases
Published in Nature communications (12-01-2021)“…Pemphigoid diseases refer to a group of severe autoimmune skin blistering diseases characterized by subepidermal blistering and loss of dermal-epidermal…”
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Granzyme K mediates IL-23-dependent inflammation and keratinocyte proliferation in psoriasis
Published in Frontiers in immunology (05-06-2024)“…Psoriasis is an inflammatory disease with systemic manifestations that most commonly presents as itchy, erythematous, scaly plaques on extensor surfaces…”
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Epithelial-Mesenchymal Plasticity Induced by Discontinuous Exposure to TGFβ1 Promotes Tumour Growth
Published in Biology (Basel, Switzerland) (12-07-2022)“…Transitions between epithelial and mesenchymal cellular states (EMT/MET) contribute to cancer progression. We hypothesize that EMT followed by MET promotes…”
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Of Germ Cells, Trophoblasts, and Cancer Stem Cells
Published in Integrative cancer therapies (01-12-2008)“…The trophoblastic theory of cancer, proposed in the early 1900s by Dr John Beard, may not initially seem relevant to current cancer models and treatments…”
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The testosterone-dependent and independent transcriptional networks in the hypothalamus of Gpr54 and Kiss1 knockout male mice are not fully equivalent
Published in BMC genomics (28-04-2011)“…Humans and mice with loss of function mutations in GPR54 (KISS1R) or kisspeptin do not progress through puberty, caused by a failure to release GnRH. The…”
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Patient Recall Is Poor Following Cosmetic Treatment With Neuromodulators and Fillers
Published in Dermatologic surgery (01-04-2021)Get full text
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Delayed Inflammatory Reaction to VYC-25L Hyaluronic Acid Filler in a Patient Without a Reaction to VYC-20L
Published in Dermatologic surgery (01-05-2021)Get full text
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Molecular classification defines outcomes and opportunities in young women with endometrial carcinoma
Published in Gynecologic oncology (01-06-2019)“…Approximately 15% of endometrial carcinomas (ECs) arise in young women who may wish to avoid surgical menopause and/or preserve fertility. Our aim was to…”
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Aesthetic medicine during COVID‐19: Patient perspectives and motivations amidst a pandemic
Published in Journal of cosmetic dermatology (01-03-2021)Get full text
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Pediatric longitudinal melanonychia
Published in Canadian Medical Association journal (CMAJ) (28-08-2017)“…Burleigh provides details on a 9-year-old boy of Asian descent was referred to the outpatient pediatric dermatology clinic with an asymptomatic linear brown…”
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Topical rapamycin (sirolimus) for the treatment of uncomplicated tufted angiomas in two children and review of the literature
Published in Pediatric dermatology (01-09-2018)“…The mTOR inhibitor rapamycin is used systemically for the treatment of vascular lesions. We report the first use of topical rapamycin for the successful…”
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Clinical and pathological characterization of endometrial cancer in young women: Identification of a cohort without classical risk factors
Published in Gynecologic oncology (01-07-2015)“…Abstract Objective Endometrial cancer (EC) is the most common gynecologic malignancy with known risk factors including excess estrogen and hereditary…”
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Mutational evolution in a lobular breast tumour profiled at single nucleotide resolution
Published in Nature (London) (08-10-2009)“…Recent advances in next generation sequencing have made it possible to precisely characterize all somatic coding mutations that occur during the development…”
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Determinants of Microcystic Adnexal Carcinoma Management and Outcomes in British Columbia
Published in Journal of cutaneous medicine and surgery (01-09-2020)Get full text
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Clinical Recognition of Merkel Cell Carcinoma by Dermatologists and Nondermatologists
Published in Journal of cutaneous medicine and surgery (01-03-2020)Get full text
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A mobile yellow nodule under the foreskin of a toddler
Published in Paediatrics & child health (01-11-2017)Get full text
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A co-culture genome-wide RNAi screen with mammary epithelial cells reveals transmembrane signals required for growth and differentiation
Published in Breast cancer research : BCR (09-01-2015)“…The extracellular signals regulating mammary epithelial cell growth are of relevance to understanding the pathophysiology of mammary epithelia, yet they remain…”
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ZNF703 is a common Luminal B breast cancer oncogene that differentially regulates luminal and basal progenitors in human mammary epithelium
Published in EMBO molecular medicine (01-03-2011)“…The telomeric amplicon at 8p12 is common in oestrogen receptor‐positive (ER+) breast cancers. Array‐CGH and expression analyses of 1172 primary breast tumours…”
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