Search Results - "Burkhardt, K"

Multiple actin networks coordinate mechanotransduction at the immunological synapse by Blumenthal, Daniel, Burkhardt, Janis K

“…Activation of naive T cells by antigen-presenting cells (APCs) is an essential step in mounting an adaptive immune response. It is known that antigen…”
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F-actin flow drives affinity maturation and spatial organization of LFA-1 at the immunological synapse by Comrie, William A, Babich, Alexander, Burkhardt, Janis K

“…Integrin-dependent interactions between T cells and antigen-presenting cells are vital for proper T cell activation, effector function, and memory. Regulation…”
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Mouse T cell priming is enhanced by maturation-dependent stiffening of the dendritic cell cortex by Blumenthal, Daniel, Chandra, Vidhi, Avery, Lyndsay, Burkhardt, Janis K

“…T cell activation by dendritic cells (DCs) involves forces exerted by the T cell actin cytoskeleton, which are opposed by the cortical cytoskeleton of the…”
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Action and Traction: Cytoskeletal Control of Receptor Triggering at the Immunological Synapse by Comrie, William A, Burkhardt, Janis K

“…It is well known that F-actin dynamics drive the micron-scale cell shape changes required for migration and immunological synapse (IS) formation. In addition,…”
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Cryptosporidium rhoptry effector protein ROP1 injected during invasion targets the host cytoskeletal modulator LMO7 by Guérin, Amandine, Roy, Nathan H., Kugler, Emily M., Berry, Laurence, Burkhardt, Janis K., Shin, Jung-Bum, Striepen, Boris

“…The parasite Cryptosporidium invades and replicates in intestinal epithelial cells and is a leading cause of diarrheal disease and early childhood mortality…”
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Actin foci facilitate activation of the phospholipase C-γ in primary T lymphocytes via the WASP pathway by Kumari, Sudha, Depoil, David, Martinelli, Roberta, Judokusumo, Edward, Carmona, Guillaume, Gertler, Frank B, Kam, Lance C, Carman, Christopher V, Burkhardt, Janis K, Irvine, Darrell J, Dustin, Michael L

“…Wiscott Aldrich Syndrome protein (WASP) deficiency results in defects in calcium ion signaling, cytoskeletal regulation, gene transcription and overall T cell…”
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Calcium influx through CRAC channels controls actin organization and dynamics at the immune synapse by Hartzell, Catherine A, Jankowska, Katarzyna I, Burkhardt, Janis K, Lewis, Richard S

“…T cell receptor (TCR) engagement opens Ca(2+) release-activated Ca(2+) (CRAC) channels and triggers formation of an immune synapse between T cells and…”
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Assembly, annotation, and comparison of Macrophomina phaseolina isolates from strawberry and other hosts by Burkhardt, Alyssa K, Childs, Kevin L, Wang, Jie, Ramon, Marina L, Martin, Frank N

“…Macrophomina phaseolina is a fungal plant pathogen with a broad host range, but one genotype was shown to exhibit host preference/specificity on strawberry…”
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Integrins Modulate T Cell Receptor Signaling by Constraining Actin Flow at the Immunological Synapse by Jankowska, Katarzyna I, Williamson, Edward K, Roy, Nathan H, Blumenthal, Daniel, Chandra, Vidhi, Baumgart, Tobias, Burkhardt, Janis K

“…Full T cell activation requires coordination of signals from multiple receptor-ligand pairs that interact in parallel at a specialized cell-cell contact site…”
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The Actin Cytoskeleton: A Mechanical Intermediate for Signal Integration at the Immunological Synapse by Roy, Nathan H, Burkhardt, Janis K

“…The immunological synapse (IS) is a specialized structure that serves as a platform for cell-cell communication between a T cell and an antigen-presenting cell…”
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Coordinate control of cytoskeletal remodeling and calcium mobilization during T-cell activation by Babich, Alexander, Burkhardt, Janis K.

“…Summary Ca2+ mobilization and cytoskeletal reorganization are key hallmarks of T‐cell activation, and their interdependence has long been recognized. Recent…”
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Stromal Notch ligands foster lymphopenia-driven functional plasticity and homeostatic proliferation of naïve B cells by Gómez Atria, Daniela, Gaudette, Brian T, Londregan, Jennifer, Kelly, Samantha, Perkey, Eric, Allman, Anneka, Srivastava, Bhaskar, Koch, Ute, Radtke, Freddy, Ludewig, Burkhard, Siebel, Christian W, Ryan, Russell Jh, Robertson, Tanner F, Burkhardt, Janis K, Pear, Warren S, Allman, David, Maillard, Ivan

“…In lymphopenic environments, secondary lymphoid organs regulate the size of B and T-cell compartments by supporting homeostatic proliferation of mature…”
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Multicenter Postmarket Analysis of the Neuroform Atlas Stent for Stent-Assisted Coil Embolization of Intracranial Aneurysms by Burkhardt, J-K, Srinivasan, V, Srivatsan, A, Albuquerque, F, Ducruet, A F, Hendricks, B, Gross, B A, Jankowitz, B T, Thomas, A J, Ogilvy, C S, Maragkos, G A, Enriquez-Marulanda, A, Crowley, R W, Levitt, M R, Kim, L J, Griessenauer, C J, Schirmer, C M, Dalal, S, Piper, K, Mokin, M, Winkler, E A, Abla, A A, McDougall, C, Birnbaum, L, Mascitelli, J, Litao, M, Tanweer, O, Riina, H, Johnson, J, Chen, S, Kan, P

“…The Neuroform Atlas is a new microstent to assist coil embolization of intracranial aneurysms that recently gained FDA approval. We present a postmarket…”
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Molecular Ordering of the Initial Signaling Events of CD95 by Algeciras-Schimnich, Alicia, Shen, Le, Barnhart, Bryan C., Murmann, Andrea E., Burkhardt, Janis K., Peter, Marcus E.

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Early Postmarket Results with EmboTrap II Stent Retriever for Mechanical Thrombectomy: A Multicenter Experience by Srivatsan, A, Srinivasan, V M, Starke, R M, Peterson, E C, Yavagal, D R, Hassan, A E, Alawieh, A, Spiotta, A M, Saleem, Y, Fargen, K M, Wolfe, S Q, de Leacy, R A, Singh, I P, Maier, I L, Johnson, J N, Burkhardt, J-K, Chen, S R, Kan, P

“…EmboTrap II is a novel stent retriever with a dual-layer design and distal mesh designed for acute ischemic stroke emergent large-vessel occlusions. We present…”
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Asymmetric B Cell Division in the Germinal Center Reaction by Barnett, Burton E., Ciocca, Maria L., Goenka, Radhika, Barnett, Lisa G., Wu, Junmin, Laufer, Terri M., Burkhardt, Janis K., Cancro, Michael P., Reiner, Steven L.

“…Lifelong antibody responses to vaccination require reorganization of lymphoid tissue and dynamic intercellular communication called the germinal center…”
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Ectromelia-encoded virulence factor C15 specifically inhibits antigen presentation to CD4+ T cells post peptide loading by Forsyth, Katherine S, Roy, Nathan H, Peauroi, Elise, DeHaven, Brian C, Wold, Erik D, Hersperger, Adam R, Burkhardt, Janis K, Eisenlohr, Laurence C

“…Smallpox and monkeypox pose severe threats to human health. Other orthopoxviruses are comparably virulent in their natural hosts, including ectromelia, the…”
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Murine chronic graft-versus-host disease proteome profiling discovers CCL15 as a novel biomarker in patients by Du, Jing, Flynn, Ryan, Paz, Katelyn, Ren, Hong-Gang, Ogata, Yuko, Zhang, Qing, Gafken, Philip R., Storer, Barry E., Roy, Nathan H., Burkhardt, Janis K., Mathews, Wendy, Tolar, Jakub, Lee, Stephanie J., Blazar, Bruce R., Paczesny, Sophie

“…Improved diagnostic and treatment methods are needed for chronic graft-versus-host disease (cGVHD), the leading cause of late nonrelapse mortality (NRM) in…”
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Fascin1 promotes cell migration of mature dendritic cells by Yamakita, Yoshihiko, Matsumura, Fumio, Lipscomb, Michael W, Chou, Po-chien, Werlen, Guy, Burkhardt, Janis K, Yamashiro, Shigeko

“…Dendritic cells (DCs) play central roles in innate and adaptive immunity. Upon maturation, DCs assemble numerous veil-like membrane protrusions, disassemble…”
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A Murine Model of X-Linked Moesin-Associated Immunodeficiency (X-MAID) Reveals Defects in T Cell Homeostasis and Migration by Avery, Lyndsay, Robertson, Tanner F, Wu, Christine F, Roy, Nathan H, Chauvin, Samuel D, Perkey, Eric, Vanderbeck, Ashley, Maillard, Ivan, Burkhardt, Janis K

“…X-linked moesin associated immunodeficiency (X-MAID) is a primary immunodeficiency disease in which patients suffer from profound lymphopenia leading to…”
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