Search Results - "Burkett, Wesley C."
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Ipatasertib, an oral AKT inhibitor, in combination with carboplatin exhibits anti-proliferative effects in uterine serous carcinoma
Published in Annals of medicine (Helsinki) (01-12-2023)“…Uterine serous carcinoma (USC) exhibits worse survival rates compared to the endometrioid subtype, and there is currently no effective treatment options for…”
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An evaluation of the microbiota of the upper reproductive tract of women with and without epithelial ovarian cancer
Published in Gynecologic oncology reports (01-08-2022)“…•There is a distinct microbiota of the upper reproductive tract.•There are differences in the microbiota composition between the ovary, fallopian tube, and…”
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Palmitic Acid Exerts Anti-Tumorigenic Activities by Modulating Cellular Stress and Lipid Droplet Formation in Endometrial Cancer
Published in Biomolecules (Basel, Switzerland) (01-05-2024)“…Epidemiological and clinical evidence have extensively documented the role of obesity in the development of endometrial cancer. However, the effect of fatty…”
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Fractured and delayed: A qualitative analysis of disruptions in care for gynecologic malignancies during incarceration
Published in Gynecologic oncology (01-09-2023)“…Women are experiencing growing rates of incarceration at twice the pace of that for men. Additionally, one-third will be older than 55 years of age by the end…”
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A Review of Current Management of Placental Site Trophoblastic Tumor and Epithelioid Trophoblastic Tumor
Published in Obstetrical & gynecological survey (01-02-2022)“…Placental site trophoblastic tumor (PSTT) and epithelioid trophoblastic tumor (ETT) are rare forms of gestational trophoblastic neoplasia (GTN). These tumors…”
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The interplay of obesity, microbiome dynamics, and innovative anti-obesity strategies in the context of endometrial cancer progression and therapeutic approaches
Published in Biochimica et biophysica acta. Reviews on cancer (01-11-2023)“…Endometrial cancer (EC) is the most common gynecologic malignancy in the United States, and its incidence and mortality are rising. Obesity is more tightly…”
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Differences in the microbial profiles of early stage endometrial cancers between Black and White women
Published in Gynecologic oncology (01-05-2022)“…Black women suffer a higher mortality from endometrial cancer (EC) than White women. Potential biological causes for this disparity include a higher prevalence…”
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Intermittent energy restriction inhibits tumor growth and enhances paclitaxel response in a transgenic mouse model of endometrial cancer
Published in Gynecologic oncology (01-07-2024)“…Overweight/obesity is the strongest risk factor for endometrial cancer (EC), and weight management can reduce that risk and improve survival. We aimed to…”
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Oleic Acid Exhibits Anti-Proliferative and Anti-Invasive Activities via the PTEN/AKT/mTOR Pathway in Endometrial Cancer
Published in Cancers (01-11-2023)“…Reprogramming of fatty acid metabolism promotes cell growth and metastasis through a variety of processes that stimulate signaling molecules, energy storage,…”
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Extending the platinum-free interval: The impact of omitting 2nd line platinum chemotherapy in intermediate platinum-sensitive ovarian cancer
Published in Gynecologic oncology (01-11-2019)“…AbstractObjectivesPatients with epithelial ovarian cancer (EOC) recurring between 6 and 12 months after primary platinum chemotherapy have worse prognosis than…”
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Adjuvant therapy for early stage, endometrial cancer with lymphovascular space invasion: Is there a role for chemotherapy?
Published in Gynecologic oncology (01-03-2020)“…Lymphovascular space invasion (LVSI) is an independent risk factor for recurrence and poor survival in early-stage endometrioid endometrial cancer (EEC), but…”
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