Search Results - "Burkes, Robert"

The role of chest computed tomography in the evaluation and management of chronic obstructive pulmonary disease by Burkes, Robert M, Zafar, Muhammad A, Panos, Ralph J

“…The purpose of this review is to compile recent data on the clinical associations of computed tomography (CT) scan findings in the literature and potential…”
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An Update on the Global Initiative for Chronic Obstructive Lung Disease 2017 Guidelines With a Focus on Classification and Management of Stable COPD by Burkes, Robert M, Donohue, James F

“…The 2017 Global Initiative for Chronic Obstructive Lung Disease (GOLD) guidelines offer important changes to the assessment and management of stable COPD of…”
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How might endotyping guide chronic obstructive pulmonary disease treatment? Current understanding, knowledge gaps and future research needs by Burkes, Robert M., Panos, Ralph J., Borchers, Michael T.

“…This review discusses emerging therapies directed at chronic obstructive pulmonary disease (COPD) endotypes and pathobiological processes that manifest as the…”
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Initiating drug therapy in early stage chronic obstructive pulmonary disease: does it impact the course and outcome? by Burkes, Robert M, Drummond, Michael B

“…PURPOSE OF REVIEWEarly chronic obstructive pulmonary disease (COPD) is emerging in importance for the clinical and research settings. This review will…”
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Plasma cathelicidin and longitudinal lung function in current and former smokers by Burkes, Robert M, Astemborski, Jacquie, Lambert, Allison A, Brown, Todd T, Wise, Robert A, Kirk, Gregory D, Drummond, M Bradley

“…Cathelicidin (also known as LL-37 in humans) is an antimicrobial peptide secreted by epithelial and immune cells and regulated by vitamin D. The immunological…”
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Associations Among 25-Hydroxyvitamin D Levels, Lung Function, and Exacerbation Outcomes in COPD: An Analysis of the SPIROMICS Cohort by Burkes, Robert M, Ceppe, Agathe S, Doerschuk, Claire M, Couper, David, Hoffman, Eric A, Comellas, Alejandro P, Barr, R Graham, Krishnan, Jerry A, Cooper, Christopher, Labaki, Wassim W, Ortega, Victor E, Wells, J Michael, Criner, Gerard J, Woodruff, Prescott G, Bowler, Russell P, Pirozzi, Cheryl S, Hansel, Nadia N, Wise, Robert A, Brown, Todd T, Drummond, M Bradley

“…The relationship between 25-hydroxyvitamin D (25-OH-vitamin D) and COPD outcomes remains unclear. Using the Subpopulations and Intermediate Outcome Measures in…”
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Considerations for and Mechanisms of Adjunct Therapy in COPD by Mandru, Rachana, Zhou, Christine Y, Pauley, Rachel, Burkes, Robert M

“…Inhaled bronchodilators and corticosteroids, when indicated, form the backbone of COPD therapy. However, over the last decade there has been an emergence of…”
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Opioid overdose leading to intensive care unit admission: Epidemiology and outcomes by Pfister, Gregory J., Burkes, Robert M., Guinn, Brian, Steele, Jacquelene, Kelley, Robert R., Wiemken, Timothy L., Saad, Mohamed, Ramirez, Julio, Cavallazzi, Rodrigo

“…There is a scarcity of studies assessing the patient population admitted to the intensive care unit (ICU) with opioid overdose. We sought to characterize the…”
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Associations of Smoking, Cytomegalovirus Serostatus, and Natural Killer Cell Phenotypes in Smokers With and At Risk for COPD by Burkes, Robert M, Bailey, Elijah, Hwalek, Timothy, Osterburg, Andrew, Lach, Laura, Panos, Ralph, Waggoner, Stephen N, Borchers, Michael T

“…Chronic obstructive disease (COPD) risk factors, smoking, and chronic infection (cytomegalovirus [CMV]) may mold natural killer (NK) cell populations. What is…”
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Impact of Quality Improvement on Care of Chronic Obstructive Pulmonary Disease Patients in an Internal Medicine Resident Clinic by Burkes, Robert M, Mkorombindo, Takudzwa, Chaddha, Udit, Bhatt, Alok, El-Kersh, Karim, Cavallazzi, Rodrigo, Kubiak, Nancy

“…Chronic obstructive pulmonary disease (COPD) is a leading cause of morbidity and mortality. Guideline-discordant care of COPD is not uncommon. Further, there…”
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Rural Residence and Chronic Obstructive Pulmonary Disease Exacerbations. Analysis of the SPIROMICS Cohort by Burkes, Robert M, Gassett, Amanda J, Ceppe, Agathe S, Anderson, Wayne, O'Neal, Wanda K, Woodruff, Prescott G, Krishnan, Jerry A, Barr, R Graham, Han, MeiLan K, Martinez, Fernando J, Comellas, Alejandro P, Lambert, Allison A, Kaufman, Joel D, Dransfield, Mark T, Wells, J Michael, Kanner, Richard E, Paine, 3rd, Robert, Bleecker, Eugene R, Paulin, Laura M, Hansel, Nadia N, Drummond, M Bradley

“…Rural residence is associated with poor outcomes in several chronic diseases. The association between rural residence and chronic obstructive pulmonary disease…”
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Diffuse Alveolar Hemorrhage Secondary to Disseminated Histoplasmosis After Kidney Transplantation by Bhatt, Alok, MBBS, Burkes, Robert, MD, Karnib, Hala, MD, Saad, Mohamed, MD

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Ultra Long-Acting β-Agonists in Chronic Obstructive Pulmonary Disease by Burkes, Robert M, Panos, Ralph J

“…Inhaled β-agonists have been foundational medications for maintenance COPD management for decades. Through activation of cyclic adenosine monophosphate…”
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Opioid overdose leading to intensive care unit admission: Epidemiology and outcomes by Burkes, Robert, MD, Pfister, Gregory, MD, Guinn, Brian, Cavallazzi, Rodrigo, MD

“…Because our study was retrospective, we were unable to accurately discern which cases were due to intentional overdose…”
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Results of a Resident-Led Quality Improvement Project on Care of Patients With COPD in an Internal Medicine Resident Teaching Clinic by Burkes, Robert, MD, Mkorombindo, Takudzwa, MD, Chaddha, Udit, MD, Bhatt, Alok, MD, Kubiak, Nancy, MD, El-Kersh, Karim, MD, Cavallazzi, Rodrigo, MD

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A Case of Relapsing Mucocutaneous Ulcers by Burkes, Robert M., Bhumbra, Nasreen A.

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Bronchoalveolar Lavage and Plasma Cathelicidin Response to 25-Hydroxy Vitamin D Supplementation: A Pilot Study by Sanders, Emily C., Burkes, Robert M., Mock, Jason R., Brown, Todd T., Wise, Robert A., Hansel, Nadia N., Liu, Mark C., Drummond, M. Bradley

“…INTRODUCTIONCathelicidin is a vitamin D-regulated, antimicrobial peptide involved in the innate immune response of the airways. Reduced plasma cathelicidin…”
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Age-Dependent Associations Between 25-Hydroxy Vitamin D Levels and COPD Symptoms: Analysis of SPIROMICS by Burkes, Robert M, Couper, David J, Barjaktarevic, Igor Z, Cooper, Christopher B, Labaki, Wassim W, Han, Meilan K, Woodruff, Prescott G, Lazarus, Stephen C, Parekh, Trisha M, Paine, 3rd, Robert, Comellas, Alejandro P, Bowler, Russell P, Loehr, Laura R, Putcha, Nirupama, Wise, Robert A, Brown, Todd T, Drummond, M Bradley

“…Age and vitamin D levels may affect symptom burden in chronic obstructive pulmonary disease (COPD). We used the Subpopulations and Intermediate Outcome…”
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Probable Levofloxacin-Induced Thrombocytopenia in a Patient Previously on Ciprofloxacin: A Case Report and Literature Review by Landi, A. Justine, Burkes, Robert

“…Drug-induced thrombocytopenia is a poorly understood, yet common phenomenon widely encountered in clinical practice. We present a case of suspected…”
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Plasma Cathelicidin is Independently Associated with Reduced Lung Function in COPD: Analysis of the Subpopulations and Intermediate Outcome Measures in COPD Study Cohort by Burkes, Robert M, Ceppe, Agathe S, Couper, David J, Comellas, Alejandro P, Wells, J Michael, Peters, Stephen P, Criner, Gerard J, Kanner, Richard E, Paine, 3rd, Robert, Christenson, Stephanie A, Cooper, Christopher B, Barjaktarevic, Igor Z, Krishnan, Jerry A, Labaki, Wassim W, Han, MeiLan K, Curtis, Jeffrey L, Hansel, Nadia N, Wise, Robert A, Drummond, M Bradley

“…The antimicrobial peptide cathelicidin, also known in humans as LL-37, is a defensin secreted by immune and airway epithelial cells. Deficiencies in this…”
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