Search Results - "Burke, Wylie"

Offering individual genetic research results: context matters by Beskow, Laura M, Burke, Wylie

“…The disclosure of individual genetic research results to study participants continues to be the subject of vigorous debate, centered primarily on the nature of…”
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Closing the gap between knowledge and clinical application: challenges for genomic translation by Burke, Wylie, Korngiebel, Diane M

“…Despite early predictions and rapid progress in research, the introduction of personal genomics into clinical practice has been slow. Several factors…”
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The cost-effectiveness of returning incidental findings from next-generation genomic sequencing by Bennette, Caroline S., Gallego, Carlos J., Burke, Wylie, Jarvik, Gail P., Veenstra, David L.

“…Purpose: The American College of Medical Genetics and Genomics (ACMG) recommended that clinical laboratories performing next-generation sequencing analyze and…”
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ASHG Statement on Direct-to-Consumer Genetic Testing in the United States by Hudson, Kathy, Javitt, Gail, Burke, Wylie, Byers, Peter

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Next-Generation Sequencing Panels for the Diagnosis of Colorectal Cancer and Polyposis Syndromes: A Cost-Effectiveness Analysis by Gallego, Carlos J, Shirts, Brian H, Bennette, Caroline S, Guzauskas, Greg, Amendola, Laura M, Horike-Pyne, Martha, Hisama, Fuki M, Pritchard, Colin C, Grady, William M, Burke, Wylie, Jarvik, Gail P, Veenstra, David L

“…To evaluate the cost effectiveness of next-generation sequencing (NGS) panels for the diagnosis of colorectal cancer and polyposis (CRCP) syndromes in patients…”
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Whole-Genome Sequencing in Healthy People by Lindor, Noralane M., MD, Thibodeau, Stephen N., PhD, Burke, Wylie, MD, PhD

“…Abstract Recent technological advances have radically changed genetic testing from an expensive and burdensome undertaking to a rapid and less costly option…”
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ASHG Statement on Direct-to-Consumer Genetic Testing in the United States by Hudson, Kathy, Javitt, Gail, Burke, Wylie, Byers, Peter

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Genetic counseling and testing for Alzheimer disease: Joint practice guidelines of the American College of Medical Genetics and the National Society of Genetic Counselors by Goldman, Jill S., Hahn, Susan E., Catania, Jennifer Williamson, Larusse-Eckert, Susan, Butson, Melissa Barber, Rumbaugh, Malia, Strecker, Michelle N., Roberts, J. Scott, Burke, Wylie, Mayeux, Richard, Bird, Thomas

“…Alzheimer disease is the most common cause of dementia. It occurs worldwide and affects all ethnic groups. The incidence of Alzheimer disease is increasing…”
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Explaining the Black-White Disparity in Preterm Birth: A Consensus Statement From a Multi-Disciplinary Scientific Work Group Convened by the March of Dimes by Braveman, Paula, Dominguez, Tyan Parker, Burke, Wylie, Dolan, Siobhan M, Stevenson, David K, Jackson, Fleda Mask, Collins, Jr, James W, Driscoll, Deborah A, Haley, Terinney, Acker, Julia, Shaw, Gary M, McCabe, Edward R B, Hay, Jr, William W, Thornburg, Kent, Acevedo-Garcia, Dolores, Cordero, José F, Wise, Paul H, Legaz, Gina, Rashied-Henry, Kweli, Frost, Jordana, Verbiest, Sarah, Waddell, Lisa

“…In 2017-2019, the March of Dimes convened a workgroup with biomedical, clinical, and epidemiologic expertise to review knowledge of the causes of the…”
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Genomic research and wide data sharing: Views of prospective participants by Trinidad, Susan Brown, Fullerton, Stephanie M., Bares, Julie M., Jarvik, Gail P., Larson, Eric B., Burke, Wylie

“…Sharing study data within the research community generates tension between two important goods: promoting scientific goals and protecting the privacy interests…”
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Effectiveness of the Family Heart Talk Communication Tool in Improving Family Member Screening for Dilated Cardiomyopathy: Results of a Randomized Trial by Kinnamon, Daniel D., Jordan, Elizabeth, Haas, Garrie J., Hofmeyer, Mark, Kransdorf, Evan, Ewald, Gregory A., Morris, Alanna A., Owens, Anjali, Lowes, Brian, Stoller, Douglas, Tang, W.H. Wilson, Garg, Sonia, Trachtenberg, Barry H., Shah, Palak, Pamboukian, Salpy V., Sweitzer, Nancy K., Wheeler, Matthew T., Wilcox, Jane E., Katz, Stuart, Pan, Stephen, Jimenez, Javier, Aaronson, Keith D., Fishbein, Daniel P., Smart, Frank, Wang, Jessica, Gottlieb, Stephen S., Judge, Daniel P., Moore, Charles K., Mead, Jonathan O., Huggins, Gordon S., Ni, Hanyu, Burke, Wylie, Hershberger, Ray E.

“…Managing disease risk among first-degree relatives of probands diagnosed with a heritable disease is central to precision medicine. A critical component is…”
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African immigrants' favorable preterm birth rates challenge genetic etiology of the Black-White disparity in preterm birth by Braveman, Paula, Heck, Katherine, Dominguez, Tyan Parker, Marchi, Kristen, Burke, Wylie, Holm, Nicole

“…We examined over a million California birth records for 2010 through 2021 to investigate whether disparities in preterm birth (PTB) by nativity and race…”
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Processes and preliminary outputs for identification of actionable genes as incidental findings in genomic sequence data in the Clinical Sequencing Exploratory Research Consortium by Berg, Jonathan S., Amendola, Laura M., Eng, Christine, Van Allen, Eliezer, Gray, Stacy W., Wagle, Nikhil, Rehm, Heidi L., DeChene, Elizabeth T., Dulik, Matthew C., Hisama, Fuki M., Burke, Wylie, Spinner, Nancy B., Garraway, Levi, Green, Robert C., Plon, Sharon, Evans, James P., Jarvik, Gail P.

“…As genomic and exomic testing expands in both the research and clinical arenas, determining whether, how, and which incidental findings to return to the…”
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Data Management in Health-Related Research Involving Indigenous Communities in the United States and Canada: A Scoping Review by Woodbury, R Brian, Beans, Julie A, Hiratsuka, Vanessa Y, Burke, Wylie

“…Multiple factors, including experiences with unethical research practices, have made some Indigenous groups in the United States and Canada reticent to…”
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Informed Consent in Translational Genomics: Insufficient Without Trustworthy Governance by Burke, Wylie, Beskow, Laura M., Trinidad, Susan Brown, Fullerton, Stephanie M., Brelsford, Kathleen

“…Neither the range of potential results from genomic research that might be returned to participants nor future uses of stored data and biospecimens can be…”
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Carnitine palmitoyltransferase 1A P479L and infant death: policy implications of emerging data by Fohner, Alison E., Garrison, Nanibaa’ A., Austin, Melissa A., Burke, Wylie

“…Carnitine palmitoyltransferase 1 isoform A (CPT1A) is a crucial enzyme for the transport of long-chain fatty acids into the mitochondria. The CPT1A p.P479L…”
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The path from genome-based research to population health: development of an international public health genomics network by Burke, Wylie, Khoury, Muin J, Stewart, Alison, Zimmern, Ronald L

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Essential elements of personalized medicine by Burke, Wylie, M.D., Ph.D, Brown Trinidad, Susan, M.A, Press, Nancy A., Ph.D

“…Summary Objectives Genomic information has been promoted as the basis for “personalized” health care. We considered the benefits provided by genomic testing in…”
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Current Priorities for Public Health Practice in Addressing the Role of Human Genomics in Improving Population Health by Khoury, Muin J., MD, PhD, Bowen, Michael S., MPH, Burke, Wylie, MD, PhD, Coates, Ralph J., PhD, Dowling, Nicole F., PhD, Evans, James P., MD, PhD, Reyes, Michele, PhD, St. Pierre, Jeannette, MA, MPH

“…Abstract In spite of accelerating human genome discoveries in a wide variety of diseases of public health significance, the promise of personalized health care…”
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Genetic testing in primary care by Burke, Wylie

“…Rapid advances in genetic research are leading to an expanding array of genetic tests. Primary care providers will increasingly be challenged to identify…”
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