Feature-tracking myocardial strain in healthy adults- a magnetic resonance study at 3.0 tesla

Feature-tracking myocardial strain in healthy adults- a magnetic resonance study at 3.0 tesla

We analyzed feature-tracking derived circumferential and longitudinal strain in healthy volunteers who underwent cardiac magnetic resonance imaging (CMR) at 3.0 T. 88 healthy adults (44.6 ± 18.0 years old, 49% male), without prior cardiovascular disease, underwent CMR at 3.0 T including cine, and la...

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Bibliographic Details
Published in:Scientific reports Vol. 9; no. 1; p. 3239
Main Authors: Mangion, Kenneth, Burke, Nicole M. M., McComb, Christie, Carrick, David, Woodward, Rosemary, Berry, Colin
Format: Journal Article
Language:English
Published: London Nature Publishing Group UK 01-03-2019
Nature Publishing Group
Subjects:
59/57
631/114/1564
692/4019/592
Adult
Aging
Aging - physiology
Bias
Cardiovascular diseases
Ejection fraction
FDA approval
Female
Females
Gadolinium
Health
Heart - diagnostic imaging
Heart - physiology
Humanities and Social Sciences
Humans
Magnetic Resonance Imaging
Male
multidisciplinary
Myocardium
Observer Variation
Reproducibility
Reproducibility of Results
Science
Science (multidisciplinary)
Sex Characteristics
Standard deviation
Ventricular Function - physiology
Volunteers
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Summary:We analyzed feature-tracking derived circumferential and longitudinal strain in healthy volunteers who underwent cardiac magnetic resonance imaging (CMR) at 3.0 T. 88 healthy adults (44.6 ± 18.0 years old, 49% male), without prior cardiovascular disease, underwent CMR at 3.0 T including cine, and late gadolinium enhancement in subjects >45 years. LV functional analysis and feature-tracking strain analyses were carried out. Global strain had better reproducibility than segmental strain. There was a sex specific difference global longitudinal strain (mean ± SD, −18.48 ± 3.65% (male), −21.91 ± 3.01% (female), p < 0.001), but not global circumferential strain (mean ± SD, −25.41 ± 4.50% (male), −27.94 ± 3.48% (female), p = 0.643). There was no association of strain with ageing after accounting for sex for both global longitudinal and circumferential strain. Feature-tracking strain analysis is feasible at 3.0 T. Healthy female volunteers demonstrated higher magnitudes of global longitudinal strain when compared to male counterparts. Whilst global cine-strain has good reproducibility, segmental strain does not.
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content type line 23
ISSN:2045-2322
2045-2322
DOI:10.1038/s41598-019-39807-w