Search Results - "Burke, Katherine M."
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A novel digital tool for detection and monitoring of amyotrophic lateral sclerosis motor impairment and progression via keystroke dynamics
Published in Scientific reports (22-07-2024)“…Amyotrophic lateral sclerosis (ALS) is a debilitating neurodegenerative condition leading to progressive muscle weakness, atrophy, and ultimately death…”
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Wearable device and smartphone data quantify ALS progression and may provide novel outcome measures
Published in NPJ digital medicine (06-03-2023)“…Amyotrophic lateral sclerosis (ALS) therapeutic development has largely relied on staff-administered functional rating scales to determine treatment efficacy…”
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Ultrasound-guided glenohumeral joint injections for shoulder pain in ALS: A case series
Published in Frontiers in neurology (02-02-2023)“…Shoulder pain is a common secondary impairment for people living with ALS (PALS). Decreased range of motion (ROM) from weakness can lead to shoulder pathology,…”
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Tracking amyotrophic lateral sclerosis disease progression using passively collected smartphone sensor data
Published in Annals of clinical and translational neurology (01-06-2024)“…Background Passively collected smartphone sensor data provide an opportunity to study physical activity and mobility unobtrusively over long periods of time…”
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Using Smartphones to Reduce Research Burden in a Neurodegenerative Population and Assessing Participant Adherence: A Randomized Clinical Trial and Two Observational Studies
Published in JMIR mHealth and uHealth (04-02-2022)“…Smartphone studies provide an opportunity to collect frequent data at a low burden on participants. Therefore, smartphones may enable data collection from…”
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Longitudinal comparison of the self‐entry Amyotrophic Lateral Sclerosis Functional Rating Scale‐Revised (ALSFRS‐RSE) and Rasch‐Built Overall Amyotrophic Lateral Sclerosis Disability Scale (ROADS) as outcome measures in people with amyotrophic lateral sclerosis
Published in Muscle & nerve (01-10-2022)“…Introduction/aims Improved functional outcome measures in amyotrophic lateral sclerosis (ALS) would aid ALS trial design and help hasten drug discovery. We…”
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The relationship of rate and pause features to the communicative participation of people living with ALS
Published in Muscle & nerve (01-08-2024)“…Introduction/Aims Many people living with amyotrophic lateral sclerosis (PALS) report restrictions in their day‐to‐day communication (communicative…”
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Smartphone data during the COVID‐19 pandemic can quantify behavioral changes in people with ALS
Published in Muscle & nerve (01-02-2021)“…Introduction Passive data from smartphone sensors may be useful for health‐care research. Our aim was to use the coronavirus disease‐2019 (COVID‐19) pandemic…”
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Expanded access protocol (EAP) program for access to investigational products for amyotrophic lateral sclerosis (ALS)
Published in Muscle & nerve (01-06-2023)“…Introduction/Aims Expanded access protocols (EAPs) are a Food and Drug Administration (FDA)‐regulated pathway for granting access to investigational products…”
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An expanded access protocol of RT001 in amyotrophic lateral sclerosis—Initial experience with a lipid peroxidation inhibitor
Published in Muscle & nerve (01-10-2022)“…Introduction/Aims Lipid peroxidation is thought to play a biologically important role in motor neuron death in amyotrophic lateral sclerosis (ALS). 11,11…”
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Longitudinal comparison of the self-administered ALSFRS-RSE and ALSFRS-R as functional outcome measures in ALS
Published in Amyotrophic lateral sclerosis and frontotemporal degeneration (01-08-2024)“…Test the feasibility, adherence rates and optimal frequency of digital, remote assessments using the ALSFRS-RSE via a customized smartphone-based app. This…”
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Patient reported outcomes in ALS: characteristics of the self-entry ALS Functional Rating Scale-revised and the Activities-specific Balance Confidence Scale
Published in Amyotrophic lateral sclerosis and frontotemporal degeneration (02-10-2021)“…Objective: This study characterized two patient-reported outcome measures (PROMs): a patient-facing adaptation of the revised amyotrophic lateral sclerosis…”
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Upper limb movements as digital biomarkers in people with ALS
Published in EBioMedicine (01-03-2024)“…Objective evaluation of people with amyotrophic lateral sclerosis (PALS) in free-living settings is challenging. The introduction of portable digital devices,…”
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Primary lateral sclerosis natural history study - planning, designing, and early enrollment
Published in Amyotrophic lateral sclerosis and frontotemporal degeneration (03-07-2023)“…Introduction/Aims. Primary lateral sclerosis (PLS) is exceedingly rare and has been an enigmatic disease. Recent progress has drastically changed this…”
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Radiation-associated choroidal neovasculopathy
Published in Ophthalmology (Rochester, Minn.) (01-12-1999)“…To characterize a newly discovered choroidal vascular abnormality in patients who have received radiation therapy for subfoveal choroidal neovascularization…”
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Upper limb movements as digital biomarkers in people with ALSResearch in context
Published in EBioMedicine (01-03-2024)“…Background: Objective evaluation of people with amyotrophic lateral sclerosis (PALS) in free-living settings is challenging. The introduction of portable…”
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Subacute cutaneous lupus erythematosus following abemaciclib therapy for metastatic breast cancer
Published in JAAD Case Reports (01-08-2021)Get full text
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