Search Results - "Burke, Jordan E."

A natural histone H2A variant lacking the Bub1 phosphorylation site and regulated depletion of centromeric histone CENP-A foster evolvability in Candida albicans by Brimacombe, Cedric A, Burke, Jordan E, Parsa, Jahan-Yar, Catania, Sandra, O'Meara, Teresa R, Witchley, Jessica N, Burrack, Laura S, Madhani, Hiten D, Noble, Suzanne M

“…Eukaryotes have evolved elaborate mechanisms to ensure that chromosomes segregate with high fidelity during mitosis and meiosis, and yet specific aneuploidies…”
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Structural mechanisms of DNA binding and unwinding in bacterial RecQ helicases by Manthei, Kelly A., Hill, Morgan C., Burke, Jordan E., Butcher, Samuel E., Keck, James L.

“…Significance RecQ DNA helicases catalyze critical genome maintenance reactions in nearly all organisms. This study describes the crystal structure of a…”
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Structure of the yeast U2/U6 snRNA complex by Burke, Jordan E, Sashital, Dipali G, Zuo, Xiaobing, Wang, Yun-Xing, Butcher, Samuel E

“…The U2/U6 snRNA complex is a conserved and essential component of the active spliceosome that interacts with the pre-mRNA substrate and essential protein…”
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Global shape mimicry of tRNA within a viral internal ribosome entry site mediates translational reading frame selection by Au, Hilda H., Cornilescu, Gabriel, Mouzakis, Kathryn D., Ren, Qian, Burke, Jordan E., Lee, Seonghoon, Butcher, Samuel E., Jan, Eric

“…The dicistrovirus intergenic region internal ribosome entry site (IRES) adopts a triple-pseudoknotted RNA structure and occupies the core ribosomal E, P, and A…”
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Pathogenic TFG Mutations Underlying Hereditary Spastic Paraplegia Impair Secretory Protein Trafficking and Axon Fasciculation by Slosarek, Erin L., Schuh, Amber L., Pustova, Iryna, Johnson, Adam, Bird, Jennifer, Johnson, Matthew, Frankel, E.B., Bhattacharya, Nilakshee, Hanna, Michael G., Burke, Jordan E., Ruhl, David A., Quinney, Kyle, Block, Samuel, Peotter, Jennifer L., Chapman, Edwin R., Sheets, Michael D., Butcher, Samuel E., Stagg, Scott M., Audhya, Anjon

“…Length-dependent axonopathy of the corticospinal tract causes lower limb spasticity and is characteristic of several neurological disorders, including…”
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A Non-Dicer RNase III and Four Other Novel Factors Required for RNAi-Mediated Transposon Suppression in the Human Pathogenic Yeast Cryptococcus neoformans by Burke, Jordan E, Longhurst, Adam D, Natarajan, Prashanthi, Rao, Beiduo, Liu, John, Sales-Lee, Jade, Mortensen, Yasaman, Moresco, James J, Diedrich, Jolene K, Yates, 3rd, John R, Madhani, Hiten D

“…The human pathogenic yeast silences transposable elements using endo-siRNAs and an Argonaute, Ago1. Endo-siRNAs production requires the RNA-dependent RNA…”
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Evolutionary Persistence of DNA Methylation for Millions of Years after Ancient Loss of a De Novo Methyltransferase by Catania, Sandra, Dumesic, Phillip A., Pimentel, Harold, Nasif, Ammar, Stoddard, Caitlin I., Burke, Jordan E., Diedrich, Jolene K., Cooke, Sophie, Shea, Terrance, Gienger, Elizabeth, Lintner, Robert, Yates, John R., Hajkova, Petra, Narlikar, Geeta J., Cuomo, Christina A., Pritchard, Jonathan K., Madhani, Hiten D.

“…Cytosine methylation of DNA is a widespread modification of DNA that plays numerous critical roles. In the yeast Cryptococcus neoformans, CG methylation occurs…”
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Brr6 plays a role in gene recruitment and transcriptional regulation at the nuclear envelope by de Bruyn Kops, Anne, Burke, Jordan E, Guthrie, Christine

“…Correlation between transcriptional regulation and positioning of genes at the nuclear envelope is well established in eukaryotes, but the mechanisms involved…”
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Spliceosome Profiling Visualizes Operations of a Dynamic RNP at Nucleotide Resolution by Burke, Jordan E., Longhurst, Adam D., Merkurjev, Daria, Sales-Lee, Jade, Rao, Beiduo, Moresco, James J., Yates, John R., Li, Jingyi Jessica, Madhani, Hiten D.

“…Tools to understand how the spliceosome functions in vivo have lagged behind advances in the structural biology of the spliceosome. Here, methods are described…”
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Structural Analysis of Multi-Helical RNAs by NMR–SAXS/WAXS: Application to the U4/U6 di-snRNA by Cornilescu, Gabriel, Didychuk, Allison L., Rodgers, Margaret L., Michael, Lauren A., Burke, Jordan E., Montemayor, Eric J., Hoskins, Aaron A., Butcher, Samuel E.

“…NMR and SAXS (small-angle X-ray scattering)/WAXS (wide-angle X-ray scattering) are highly complementary approaches for the analysis of RNA structure in…”
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Conformational flexibility in the enterovirus RNA replication platform by Warden, Meghan S, Cai, Kai, Cornilescu, Gabriel, Burke, Jordan E, Ponniah, Komala, Butcher, Samuel E, Pascal, Steven M

“…A presumed RNA cloverleaf (5'CL), located at the 5'-most end of the noncoding region of the enterovirus genome, is the primary established site for initiation…”
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Evolutionary Persistence of DNA Methylation for Millions of Years after Ancient Loss of a De Novo Methyltransferase by Catania, Sandra, Dumesic, Phillip A., Pimentel, Harold, Nasif, Ammar, Stoddard, Caitlin I., Burke, Jordan E., Diedrich, Jolene K., Cooke, Sophie, Shea, Terrance, Gienger, Elizabeth, Lintner, Robert, Yates, John R., Hajkova, Petra, Narlikar, Geeta J., Cuomo, Christina A., Pritchard, Jonathan K., Madhani, Hiten D.

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Spliceosome assembly in the absence of stable U4/U6 RNA pairing by Burke, Jordan E, Butcher, Samuel E, Brow, David A

“…The cycle of spliceosome assembly, intron excision, and spliceosome disassembly involves large-scale structural rearrangements of U6 snRNA that are…”
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Nucleic acid structure characterization by small angle X-ray scattering (SAXS) by Burke, Jordan E, Butcher, Samuel E

“…Small angle X-ray scattering (SAXS) is a powerful method for investigating macromolecular structure in solution. SAXS data provide information about the size…”
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Evolutionary Persistence of DNA Methylation for Millions of Years after Ancient Lossof a De Novo Methyltransferase by Catania, Sandra, Dumesic, Phillip A., Pimentel, Harold, Nasif, Ammar, Stoddard, Caitlin I., Burke, Jordan E., Diedrich, Jolene K., Cooke, Sophie, Shea, Terrance, Gienger, Elizabeth, Lintner, Robert, Yates, John R., Hajkova, Petra, Narlikar, Geeta J., Cuomo, Christina A., Pritchard, Jonathan K., Madhani, Hiten D.

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Pathogenic TFG Mutations Underlying Hereditary Spastic Paraplegia Impair Secretory Protein Trafficking and Axon Fasciculation by Slosarek, Erin L., Schuh, Amber L., Pustova, Iryna, Johnson, Adam, Bird, Jennifer, Johnson, Matthew, Frankel, E. B., Bhattacharya, Nilakshee, Hanna, Michael G., Burke, Jordan E., Ruhl, David A., Quinney, Kyle, Block, Samuel, Peotter, Jennifer L., Chapman, Edwin R., Sheets, Michael D., Butcher, Samuel E., Stagg, Scott M., Audhya, Anjon

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A Non-Dicer RNase III and Four Other Novel Factors Required for RNAi-Mediated Transposon Suppression in the Human Pathogenic Yeast Cryptococcus neoformans by Burke, Jordan E, Longhurst, Adam D, Natarajan, Prashanthi, Rao, Beiduo, Liu, John, Sales-Lee, Jade, Mortensen, Yasaman, Moresco, James J, Diedrich, Jolene K, Yates, John R, Madhani, Hiten D

“…The human pathogenic yeast Cryptococcus neoformans silences transposable elements using endo-siRNAs and an Argonaute, Ago1. Endo-siRNAs production requires the…”
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The central role of the U2/U6 snRNA interaction in spliceosome structure and recycling by Burke, Jordan E

“…Splicing is an essential eukaryotic process resulting in removal of non-coding introns from messenger RNA (mRNA). This process is accomplished by assembly of a…”
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