Search Results - "Burke, G. R."

C1 neurons: the body's EMTs by Guyenet, Patrice G, Stornetta, Ruth L, Bochorishvili, Genrieta, Depuy, Seth D, Burke, Peter G R, Abbott, Stephen B G

“…The C1 neurons reside in the rostral and intermediate portions of the ventrolateral medulla (RVLM, IVLM). They use glutamate as a fast transmitter and…”
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Tyrosine hydroxylase phosphorylation in catecholaminergic brain regions: a marker of activation following acute hypotension and glucoprivation by Damanhuri, Hanafi A, Burke, Peter G R, Ong, Lin K, Bobrovskaya, Larisa, Dickson, Phillip W, Dunkley, Peter R, Goodchild, Ann K

“…The expression of c-Fos defines brain regions activated by the stressors hypotension and glucoprivation however, whether this identifies all brain sites…”
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Responses of the pea aphid transcriptome to infection by facultative symbionts by Burke, G. R., Moran, N. A.

“…Serratia symbiotica is a facultative symbiont of pea aphids (Acyrthosiphon pisum) that provides tolerance to heat stress. Although the phenotypic effects of…”
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Somatostatin 2A Receptor–Expressing Presympathetic Neurons in the Rostral Ventrolateral Medulla Maintain Blood Pressure by Burke, Peter G.R, Li, Qun, Costin, Monique L, McMullan, Simon, Pilowsky, Paul M, Goodchild, Ann K

“…Bulbospinal neurons in the rostral ventrolateral medulla (RVLM) are critical for the maintenance of sympathetic vasomotor tone and normal cardiovascular reflex…”
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Augmented Respiratory–Sympathetic Coupling and Hemodynamic Response to Acute Mild Hypoxia in Female Rodents With Chronic Kidney Disease by Saha, Manash, Sun, Qi-Jian, Hildreth, Cara M., Burke, Peter G. R., Phillips, Jacqueline K.

“…Carotid body feedback and hypoxia may serve to enhance respiratory–sympathetic nerve coupling (respSNA) and act as a driver of increased blood pressure. Using…”
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Regional associations between inspiratory tongue dilatory movement and genioglossus activity during wakefulness in people with obstructive sleep apnoea by Jugé, Lauriane, Liao, Angela, Yeung, Jade, Knapman, Fiona L., Bull, Christopher, Burke, Peter G.R., Brown, Elizabeth C., Gandevia, Simon C., Eckert, Danny J., Butler, Jane E., Bilston, Lynne E.

“…Inspiratory tongue dilatory movement is believed to be mediated via changes in neural drive to genioglossus. However, this has not been studied during quiet…”
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Host range of a parasitoid wasp is linked to host susceptibility to its mutualistic viral symbiont by Coffman, K. A., Kauwe, A. N., Gillette, N. E., Burke, G. R., Geib, S. M.

“…Parasitoid wasps are one of the most species‐rich groups of animals on Earth, due to their ability to successfully develop as parasites of nearly all types of…”
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Regional respiratory movement of the tongue is coordinated during wakefulness and is larger in severe obstructive sleep apnoea by Jugé, Lauriane, Knapman, Fiona L., Burke, Peter G.R., Brown, Elizabeth, Bosquillon de Frescheville, Anne France, Gandevia, Simon C., Eckert, Danny J., Butler, Jane E., Bilston, Lynne E.

“…Key points Coordination of the neuromuscular compartments of the tongue is critical to maintain airway patency. Currently, little is known about the extent to…”
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State‐dependent control of breathing by the retrotrapezoid nucleus by Burke, Peter G.R., Kanbar, Roy, Basting, Tyler M., Hodges, Walter M., Viar, Kenneth E., Stornetta, Ruth L., Guyenet, Patrice G.

“…Key points This study explores the state dependence of the hypercapnic ventilatory reflex (HCVR). We simulated an instantaneous increase or decrease of central…”
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Hypoxia silences retrotrapezoid nucleus respiratory chemoreceptors via alkalosis by Basting, Tyler M, Burke, Peter G R, Kanbar, Roy, Viar, Kenneth E, Stornetta, Daniel S, Stornetta, Ruth L, Guyenet, Patrice G

“…In conscious mammals, hypoxia or hypercapnia stimulates breathing while theoretically exerting opposite effects on central respiratory chemoreceptors (CRCs)…”
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Nocturnal swallowing augments arousal intensity and arousal tachycardia by Burke, P. G. R., Carter, S. G., Knapman, F., Patti, J., Butlin, M., Gandevia, S. C., Butler, J. E., Eckert, D. J., Bilston, L. E.

“…Cortical arousal from sleep is associated with autonomic activation and acute increases in heart rate. Arousals vary considerably in their frequency,…”
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Tonically Active cAMP-Dependent Signaling in the Ventrolateral Medulla Regulates Sympathetic and Cardiac Vagal Outflows by Tallapragada, Vikram J, Hildreth, Cara M, Burke, Peter G R, Raley, Darryl A, Hassan, Sarah F, McMullan, Simon, Goodchild, Ann K

“…The ventrolateral medulla contains presympathetic and vagal preganglionic neurons that control vasomotor and cardiac vagal tone, respectively. G…”
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Polysialic Acid Regulates Sympathetic Outflow by Facilitating Information Transfer within the Nucleus of the Solitary Tract by Bokiniec, Phillip, Shahbazian, Shila, McDougall, Stuart J, Berning, Britt A, Cheng, Delfine, Llewellyn-Smith, Ida J, Burke, Peter G R, McMullan, Simon, Mühlenhoff, Martina, Hildebrandt, Herbert, Braet, Filip, Connor, Mark, Packer, Nicolle H, Goodchild, Ann K

“…Expression of the large extracellular glycan, polysialic acid (polySia), is restricted in the adult, to brain regions exhibiting high levels of plasticity or…”
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Somatostatin selectively ablates post-inspiratory activity after injection into the Bötzinger complex by Burke, P.G.R, Abbott, S.B.G, McMullan, S, Goodchild, A.K, Pilowsky, P.M

“…Abstract Somatostatin (SST) neurons in the ventral respiratory column (VRC) are essential for the generation of normal breathing. Little is known about the…”
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Inhibition of protein kinase A activity depresses phrenic drive and glycinergic signalling, but not rhythmogenesis in anaesthetized rat by Burke, P. G. R., Sousa, L. O., Tallapragada, V. J., Goodchild, A. K.

“…The cAMP–protein kinase A (PKA) pathway plays a critical role in regulating neuronal activity. Yet, how PKA signalling shapes the population activity of…”
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Role of the Kölliker–Fuse/parabrachial complex in the generation of postinspiratory vagal and sympathetic nerve activities and their recruitment by hypoxemic stimuli in the rat by Toor, Rahat Ul Ain Summan, Burke, Peter G. R., Dempsey, Bowen, Sun, Qi-Jian, Hildreth, Cara M., Phillips, Jacqueline K., McMullan, Simon

“…Inhibition of neurons in the pontine Kölliker–Fuse/parabrachial complex (KF-PBN) differentially inhibited postinspiratory (post-I) activity in vagal and…”
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Direct optogenetic activation of upper airway muscles in an acute model of upper airway hypotonia mimicking sleep onset by Knapman, Fiona L, Cohen, E Myfanwy, Kulaga, Tom, Lovell, Nigel, Lisowski, Leszek, McMullan, Simon, Burke, Peter G R, Bilston, Lynne E

“…Abstract Study Objectives Obstructive sleep apnea (OSA), where the upper airway collapses repeatedly during sleep due to inadequate dilator muscle tone, is…”
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Do catecholaminergic TrkC DRG neurons represent a class of cardiovascular enteroceptor? by McMullan, Simon, Burke, Peter G.R., Hildreth, Cara M.

“…In a recent issue of Cell Reports, Morelli et al. (2021) identify a subpopulation of mechanosensitive peripheral sensory neurons that coexpress tyrosine…”
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Upper airway collapsibility measured using a simple wakefulness test closely relates to the pharyngeal critical closing pressure during sleep in obstructive sleep apnea by Osman, Amal M, Carberry, Jayne C, Burke, Peter G R, Toson, Barbara, Grunstein, Ronald R, Eckert, Danny J

“…A collapsible or crowded pharyngeal airway is the main cause of obstructive sleep apnea (OSA). However, quantification of airway collapsibility during sleep…”
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Dose-dependent effects of mandibular advancement on upper airway collapsibility and muscle function in obstructive sleep apnea by Bamagoos, Ahmad A, Cistulli, Peter A, Sutherland, Kate, Ngiam, Joachim, Burke, Peter G R, Bilston, Lynne E, Butler, Jane E, Eckert, Danny J

“…Mandibular advancement splints (MAS) are the leading treatment alternative to continuous positive airway pressure (CPAP) for obstructive sleep apnea (OSA)…”
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