Search Results - "Burke, Brenda J."

Synthesis of Azadirachtin: A Long but Successful Journey by Veitch, Gemma E, Beckmann, Edith, Burke, Brenda J, Boyer, Alistair, Maslen, Sarah L, Ley, Steven V

“…22 Years in the making: Azadirachtin (1) was synthesized for the first time by a highly convergent approach, utilizing a Claisen rearrangement and a radical…”
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A Relay Route for the Synthesis of Azadirachtin by Veitch, Gemma E., Beckmann, Edith, Burke, Brenda J., Boyer, Alistair, Ayats, Carles, Ley, Steven V.

“…22 Years in the making: Azadirachtin (1) was synthesized for the first time by a highly convergent approach, utilizing a Claisen rearrangement and a radical…”
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Mapping Polymorphic Behavior of Process Intermediates, an Often-Overlooked Exercise by Morrison, Henry, Regens, Christopher S, Dunetz, Joshua R, Lapina, Olga, Shah, Nisha P, Burke, Brenda J, Wenderski, Todd, Asselin, Sylvie M, Vieira, Tiago

“…Presented are two case studies where polymorphic behavior of a process intermediate was identified and the relationship was investigated for form control. Case…”
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Practical Syntheses of a CXCR3 Antagonist by Chan, Johann, Burke, Brenda J, Baucom, Kyle, Hansen, Karl, Bio, Matthew M, DiVirgilio, Evan, Faul, Margaret, Murry, Jerry

“…Two new, reliable syntheses of a pyrido[2,3-d]-pyrimidine inhibitor of the CXCR3 receptor are described. A nine-step synthesis of the CXCR3 inhibitor (1) from…”
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Enantioselective Synthesis of Six-Membered Palladacycles Having Metal-Bound Stereogenic Carbons:  Isolation and Reactivity of Palladacycles Containing Readily Accessible β-Hydrogens by Burke, Brenda J, Overman, Larry E

“…Five enantiopure palladacycles containing palladium bonded to a stereogenic carbon and an N-coordinated oxindole were synthesized by the reaction of alkenyl…”
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Cover Picture: The Synthesis of Azadirachtin: A Potent Insect Antifeedant (Chem. Eur. J. 34/2008) by Ley, Steven V., Abad-Somovilla, Antonio, Anderson, James C., Ayats, Carles, Bänteli, Rolf, Beckmann, Edith, Boyer, Alistair, Brasca, Maria G., Brice, Abigail, Broughton, Howard B., Burke, Brenda J., Cleator, Ed, Craig, Donald, Denholm, Alastair A., Denton, Ross M., Durand-Reville, Thomas, Gobbi, Luca B., Göbel, Michael, Gray, Brian Lawrence, Grossmann, Robert B., Gutteridge, Claire E., Hahn, Norbert, Harding, Sarah L., Jennens, David C., Jennens, Lynn, Lovell, Peter J., Lovell, Helen J., de la Puente, Mary L., Kolb, Hartmuth C., Koot, Win-Jan, Maslen, Sarah L., McCusker, Catherine F., Mattes, Amos, Pape, Andrew R., Pinto, Andrea, Santafianos, Dinos, Scott, James S., Smith, Stephen C., Somers, Andrew Q., Spilling, Christopher D., Stelzer, Frank, Toogood, Peter L., Turner, Richard M., Veitch, Gemma E., Wood, Anthony, Zumbrunn, Cornelia

“…An exceptionally challenging synthesis target has finally met its match. An avenue of neem trees flanks an outline of the Ley azadirachtin synthesis road map…”
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Impact of ICH Q11 Questions and Answers on the Outcome of Active Pharmaceutical Ingredient Starting Material Proposal Acceptance by ICH Regulatory Members by Tymonko, Steven, Burke, Brenda J., Crochard, Jean-Philippe, Dirat, Olivier, Fraunhoffer, Kenneth J., Harrison, Cristian, Kramer, Timothy, Lee, Heewon, Liberman, Vlad, Sidhu, Kanwar P. S., Smith, Randi, Strotman, Neil A., Tandogan, Nil, Triman, Alan, Zhang, Haitao

“…The designation and justification of active pharmaceutical ingredient starting materials (API SMs) is a crucial aspect of the drug substance (DS)…”
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Synthesis of Azadirachtin: A Long but Successful Journey by Veitch, Gemma E., Beckmann, Edith, Burke, Brenda J., Boyer, Alistair, Maslen, Sarah L., Ley, Steven V.

“…Nach 22 Jahren konnte die Totalsynthese von Azadirachtin (1) zum Abschluss gebracht werden. Die hoch konvergente Syntheseroute setzte auf eine…”
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A Relay Route for the Synthesis of Azadirachtin by Veitch, Gemma E., Beckmann, Edith, Burke, Brenda J., Boyer, Alistair, Ayats, Carles, Ley, Steven V.

“…Nach 22 Jahren konnte die Totalsynthese von Azadirachtin (1) zum Abschluss gebracht werden. Die hoch konvergente Syntheseroute setzte auf eine…”
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The Synthesis of Azadirachtin: A Potent Insect Antifeedant by Ley, Steven V., Abad-Somovilla, Antonio, Anderson, James C., Ayats, Carles, Bänteli, Rolf, Beckmann, Edith, Boyer, Alistair, Brasca, Maria G., Brice, Abigail, Broughton, Howard B., Burke, Brenda J., Cleator, Ed, Craig, Donald, Denholm, Alastair A., Denton, Ross M., Durand-Reville, Thomas, Gobbi, Luca B., Göbel, Michael, Gray, Brian Lawrence, Grossmann, Robert B., Gutteridge, Claire E., Hahn, Norbert, Harding, Sarah L., Jennens, David C., Jennens, Lynn, Lovell, Peter J., Lovell, Helen J., de la Puente, Mary L., Kolb, Hartmuth C., Koot, Win-Jan, Maslen, Sarah L., McCusker, Catherine F., Mattes, Amos, Pape, Andrew R., Pinto, Andrea, Santafianos, Dinos, Scott, James S., Smith, Stephen C., Somers, Andrew Q., Spilling, Christopher D., Stelzer, Frank, Toogood, Peter L., Turner, Richard M., Veitch, Gemma E., Wood, Anthony, Zumbrunn, Cornelia

“…We describe in full the first synthesis of the potent insect antifeedant azadirachtin through a highly convergent approach. An O‐alkylation reaction is used to…”
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Cover Picture: Synthesis of Azadirachtin: A Long but Successful Journey (Angew. Chem. Int. Ed. 40/2007) by Veitch, Gemma E., Beckmann, Edith, Burke, Brenda J., Boyer, Alistair, Maslen, Sarah L., Ley, Steven V.

“…The neem tree in the foreground of the cover picture is the natural source of azadirachtin, a complex molecule containing sixteen contiguous stereogenic…”
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Titelbild: Synthesis of Azadirachtin: A Long but Successful Journey (Angew. Chem. 40/2007) by Veitch, Gemma E., Beckmann, Edith, Burke, Brenda J., Boyer, Alistair, Maslen, Sarah L., Ley, Steven V.

“…Der Niembaum im Bildvordergrund ist die natürliche Quelle von Azadirachtin, einem komplexen Molekül mit 16 aufeinander folgenden Stereozentren, darunter sieben…”
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Synthesis of Azadirachtin: A Long but Successful Journey by Veitch, Gemma E., Beckmann, Edith, Burke, Brenda J., Boyer, Alistair, Maslen, Sarah L., Ley, Steven V.

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A Relay Route for the Synthesis of Azadirachtin by Veitch, Gemma E., Beckmann, Edith, Burke, Brenda J., Boyer, Alistair, Ayats, Carles, Ley, Steven V.

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Titelbild: Synthesis of Azadirachtin: A Long but Successful Journey (Angew. Chem. 40/2007) by Veitch, Gemma E., Beckmann, Edith, Burke, Brenda J., Boyer, Alistair, Maslen, Sarah L., Ley, Steven V.

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