Search Results - "Burguillos, Miguel A"

Microglia: Agents of the CNS Pro-Inflammatory Response by Rodríguez-Gómez, José A, Kavanagh, Edel, Engskog-Vlachos, Pinelopi, Engskog, Mikael K R, Herrera, Antonio J, Espinosa-Oliva, Ana M, Joseph, Bertrand, Hajji, Nabil, Venero, José L, Burguillos, Miguel A

“…The pro-inflammatory immune response driven by microglia is a key contributor to the pathogenesis of several neurodegenerative diseases. Though the research of…”
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Glioma-induced inhibition of caspase-3 in microglia promotes a tumor-supportive phenotype by Shen, Xianli, Burguillos, Miguel A, Osman, Ahmed M, Frijhoff, Jeroen, Carrillo-Jiménez, Alejandro, Kanatani, Sachie, Augsten, Martin, Saidi, Dalel, Rodhe, Johanna, Kavanagh, Edel, Rongvaux, Anthony, Rraklli, Vilma, Nyman, Ulrika, Holmberg, Johan, Östman, Arne, Flavell, Richard A, Barragan, Antonio, Venero, Jose Luis, Blomgren, Klas, Joseph, Bertrand

“…Gliomas recruit and manipulate microglial function to promote their growth. Joseph and colleagues reveal the molecular basis of this manipulation by showing…”
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Use of meso-scale discovery™ to examine cytokine content in microglia cell supernatant by Burguillos, Miguel A

“…Cytokine production by activated microglia is one of the hallmarks of inflammatory response in the CNS. The cytokines released by microglia cells can be very…”
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Microchannel acoustophoresis does not impact survival or function of microglia, leukocytes or tumor cells by Burguillos, Miguel A, Magnusson, Cecilia, Nordin, Maria, Lenshof, Andreas, Augustsson, Per, Hansson, Magnus J, Elmér, Eskil, Lilja, Hans, Brundin, Patrik, Laurell, Thomas, Deierborg, Tomas

“…The use of acoustic forces to manipulate particles or cells at the microfluidic scale (i.e. acoustophoresis), enables non-contact, label-free separation based…”
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Docosahexaenoic acid reduces microglia phagocytic activity via miR-124 and induces neuroprotection in rodent models of spinal cord contusion injury by Yip, Ping K, Bowes, Amy L, Hall, Jodie C E, Burguillos, Miguel A, Ip, T H Richard, Baskerville, Tracey, Liu, Zhuo-Hao, Mohamed, Moumin A E K, Getachew, Fanuelle, Lindsay, Anna D, Najeeb, Saif-Ur-Rehman, Popovich, Phillip G, Priestley, John V, Michael-Titus, Adina T

“…Abstract Microglia are activated after spinal cord injury (SCI), but their phagocytic mechanisms and link to neuroprotection remain incompletely characterized…”
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Caspases playing in the field of neuroinflammation: old and new players by Venero, Jose L, Burguillos, Miguel A, Joseph, Bertrand

“…Neuroinflammation is a complex immune response against the harmful effects of diverse stimuli within the central nervous system. Caspases are a family of…”
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Neuromelanin activates proinflammatory microglia through a caspase-8-dependent mechanism by Viceconte, Nikenza, Burguillos, Miguel A, Herrera, Antonio J, De Pablos, Rocío M, Joseph, Bertrand, Venero, José L

“…We have uncovered a caspase-dependent (caspase-8/caspase-3/7) signaling governing microglia activation and associated neurotoxicity. Importantly, a profuse…”
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A nutrient combination designed to enhance synapse formation and function improves outcome in experimental spinal cord injury by Pallier, Patrick N, Poddighe, Laura, Zbarsky, Virginia, Kostusiak, Milosz, Choudhury, Rasall, Hart, Thomas, Burguillos, Miguel A, Musbahi, Omar, Groenendijk, Martine, Sijben, John W, deWilde, Martijn C, Quartu, Marina, Priestley, John V, Michael-Titus, Adina T

“…Abstract Spinal cord injury leads to major neurological impairment for which there is currently no effective treatment. Recent clinical trials have…”
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Caspase signalling controls microglia activation and neurotoxicity by Burguillos, Miguel A., Deierborg, Tomas, Kavanagh, Edel, Persson, Annette, Hajji, Nabil, Garcia-Quintanilla, Albert, Cano, Josefina, Brundin, Patrik, Englund, Elisabet, Venero, Jose L., Joseph, Bertrand

“…Activation of microglia and inflammation-mediated neurotoxicity are suggested to play a decisive role in the pathogenesis of several neurodegenerative…”
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Wild-type sTREM2 blocks Aβ aggregation and neurotoxicity, but the Alzheimer's R47H mutant increases Aβ aggregation by Vilalta, Anna, Zhou, Ye, Sevalle, Jean, Griffin, Jennifer K., Satoh, Kanayo, Allendorf, David H., De, Suman, Puigdellívol, Mar, Bruzas, Arturas, Burguillos, Miguel A., Dodd, Roger B., Chen, Fusheng, Zhang, Yalun, Flagmeier, Patrick, Needham, Lisa-Maria, Enomoto, Masahiro, Qamar, Seema, Henderson, James, Walter, Jochen, Fraser, Paul E., Klenerman, David, Lee, Steven F., St George-Hyslop, Peter, Brown, Guy C.

“…TREM2 is a pattern recognition receptor, expressed on microglia and myeloid cells, detecting lipids and Aβ and inducing an innate immune response. Missense…”
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A new "sweet" ligand for Toll-like receptor 4 by Deierborg, Tomas, Burguillos, Miguel A

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Guilt by association, caspase-3 regulates microglia polarization by Shen, Xianli, Burguillos, Miguel A., Joseph, Bertrand

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The novel component Kgd4 recruits the E3 subunit to the mitochondrial α-ketoglutarate dehydrogenase by Heublein, Manfred, Burguillos, Miguel A, Vögtle, F Nora, Teixeira, Pedro F, Imhof, Axel, Meisinger, Chris, Ott, Martin

“…The mitochondrial citric acid cycle is a central hub of cellular metabolism, providing intermediates for biosynthetic pathways and channeling electrons to the…”
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Reformulating Pro-Oxidant Microglia in Neurodegeneration by García-Revilla, Juan, Alonso-Bellido, Isabel M, Burguillos, Miguel A, Herrera, Antonio J, Espinosa-Oliva, Ana M, Ruiz, Rocío, Cruz-Hernández, Luis, García-Domínguez, Irene, Roca-Ceballos, María A, Santiago, Marti, Rodríguez-Gómez, José A, Soto, Manuel Sarmiento, de Pablos, Rocío M, Venero, José L

“…In neurodegenerative diseases, microglia-mediated neuroinflammation and oxidative stress are central events. Recent genome-wide transcriptomic analyses of…”
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Preservation of aortic root architecture and properties using a detergent-enzymatic perfusion protocol by Friedrich, Linda H, Jungebluth, Philipp, Sjöqvist, Sebastian, Lundin, Vanessa, Haag, Johannes C, Lemon, Greg, Gustafsson, Ylva, Ajalloueian, Fatemeh, Sotnichenko, Alexander, Kielstein, Heike, Burguillos, Miguel A, Joseph, Bertrand, Teixeira, Ana I, Lim, Mei Ling, Macchiarini, Paolo

“…Abstract Aortic valve degeneration and dysfunction is one of the leading causes for morbidity and mortality. The conventional heart-valve prostheses have…”
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Spatio-temporal activation of caspase-8 in myeloid cells upon ischemic stroke by Rodhe, Johanna, Burguillos, Miguel A, de Pablos, Rocio M, Kavanagh, Edel, Persson, Annette, Englund, Elisabet, Deierborg, Tomas, Venero, Jose L, Joseph, Bertrand

“…Ischemic stroke (caused by thrombosis, embolism or vasoconstriction) lead to the recruitment and activation of immune cells including resident microglia and…”
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Radiosensitizer effect of wortmannin in radioresistant bladder tumoral cell lines by Ortiz, Trinidad, Lopez, Sergio, Burguillos, Miguel A, Edreira, Aymee, Piñero, Joaquin

“…This work analyzes the effectiveness of wortmannin in boosting the lethality induced by different doses of X-rays, using the colorimetric assay of MTT. Bladder…”
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Microchannel Acoustophoresis does not Impact Survival or Function of Microglia, Leukocytes or Tumor Cells. e64233 by Burguillos, Miguel A, Magnusson, Cecilia, Nordin, Maria, Lenshof, Andreas, Augustsson, Per, Hansson, Magnus J, Elmer, Eskil, Lilja, Hans, Brundin, Patrik, Laurell, Thomas

“…Background The use of acoustic forces to manipulate particles or cells at the microfluidic scale (i.e. acoustophoresis), enables non-contact, label-free…”
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