Search Results - "Burgin, Antonia Marin"
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Unique Processing During a Period of High Excitation/Inhibition Balance in Adult-Born Neurons
Published in Science (American Association for the Advancement of Science) (09-03-2012)“…The adult dentate gyrus generates new granule cells (GCs) that develop over several weeks and integrate into the preexisting network. Although adult…”
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αSynuclein control of mitochondrial homeostasis in human-derived neurons is disrupted by mutations associated with Parkinson’s disease
Published in Scientific reports (11-07-2017)“…The etiology of Parkinson’s disease (PD) converges on a common pathogenic pathway of mitochondrial defects in which α-Synuclein (αSyn) is thought to play a…”
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3
Ascl1 Balances Neuronal versus Ependymal Fate in the Spinal Cord Central Canal
Published in Cell reports (Cambridge) (27-08-2019)“…Generation of neuronal types at the right time, location, and number is essential for building a functional nervous system. Significant progress has been…”
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Requirement of adult-born neurons for hippocampus-dependent learning
Published in Behavioural brain research (14-02-2012)“…A fundamental question in the field of adult neurogenesis relies in addressing whether neurons generated in the adult dentate gyrus are needed for hippocampal…”
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Acquisition of non-olfactory encoding improves odour discrimination in olfactory cortex
Published in Nature communications (02-07-2024)“…Olfaction is influenced by contextual factors, past experiences, and the animal’s internal state. Whether this information is integrated at the initial stages…”
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6
Input normalization by global feedforward inhibition expands cortical dynamic range
Published in Nature neuroscience (01-12-2009)“…The cortex is sensitive to weak stimuli, but also responds to stronger inputs without saturating. In this study, Scanziani and colleagues find some of the…”
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From synapses to behavior: Development of a sensory‐motor circuit in the leech
Published in Developmental neurobiology (Hoboken, N.J.) (01-05-2008)“…The development of neuronal circuits has been advanced greatly by the use of imaging techniques that reveal the activity of neurons during the period when they…”
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Adult-born granule cells improve stimulus encoding and discrimination in the dentate gyrus
Published in eLife (16-08-2023)“…Heterogeneity plays an important role in diversifying neural responses to support brain function. Adult neurogenesis provides the dentate gyrus with a…”
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The late and dual origin of cerebrospinal fluid-contacting neurons in the mouse spinal cord
Published in Development (Cambridge) (01-03-2016)“…Considerable progress has been made in understanding the mechanisms that control the production of specialized neuronal types. However, how the timing of…”
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10
Cholinergic modulation of dentate gyrus processing through dynamic reconfiguration of inhibitory circuits
Published in Cell reports (Cambridge) (24-08-2021)“…The dentate gyrus (DG) of the hippocampus plays a key role in memory formation, and it is known to be modulated by septal projections. By performing…”
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11
Differential inhibition onto developing and mature granule cells generates high-frequency filters with variable gain
Published in eLife (11-07-2015)“…Adult hippocampal neurogenesis provides the dentate gyrus with heterogeneous populations of granule cells (GC) originated at different times. The contribution…”
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12
Widespread Inhibition Proportional to Excitation Controls the Gain of a Leech Behavioral Circuit
Published in Neuron (Cambridge, Mass.) (24-01-2008)“…Changing gain in a neuronal system has important functional consequences, but the underlying mechanisms have been elusive. Models have suggested a variety of…”
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13
Low-threshold heat response antagonized by capsazepine in chick sensory neurons, which are capsaicin-insensitive
Published in The European journal of neuroscience (01-10-2000)“…The heat‐transducing receptor VR1 cloned from rat sensory neurons can be activated by both noxious heat and capsaicin. As the response of sensory neurons to…”
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14
Lateral entorhinal cortex afferents reconfigure the activity in piriform cortex circuits
Published in Proceedings of the National Academy of Sciences - PNAS (26-11-2024)“…Odors are key signals for guiding spatial behaviors such as foraging and navigation in rodents. Recent findings reveal that odor representations in the…”
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15
A dye mixture (Neurobiotin and Alexa 488) reveals extensive dye-coupling among neurons in leeches; physiology confirms the connections
Published in Journal of Comparative Physiology (01-12-2005)“…Although the neuronal circuits that generate leech movements have been studied for over 30 years, the list of interneurons (INs) in these circuits remains…”
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Sequential Development of Electrical and Chemical Synaptic Connections Generates a Specific Behavioral Circuit in the Leech
Published in The Journal of neuroscience (09-03-2005)“…Neuronal circuits form during embryonic life, even before synapses are completely mature. Developmental changes can be quantitative (e.g., connections become…”
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Deletion of dopamine D₂ receptors from parvalbumin interneurons in mouse causes schizophrenia-like phenotypes
Published in Proceedings of the National Academy of Sciences - PNAS (27-03-2018)“…Excessive dopamine neurotransmission underlies psychotic episodes as observed in patients with some types of bipolar disorder and schizophrenia. The…”
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18
Tau conditional reduction in human‐derived neurons exposes novel tau‐associated functions in electrical activity and axonal transport
Published in Alzheimer's & dementia (01-12-2021)“…Background Abnormal tau accumulation is the hallmark of neurodegenerative diseases, and gain‐of‐toxic tau function has been pointed as triggering neuronal…”
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Deletion of dopamine D^sub 2^ receptors from parvalbumin interneurons in mouse causes schizophrenia-like phenotypes
Published in Proceedings of the National Academy of Sciences - PNAS (27-03-2018)“…Excessive dopamine neurotransmission underlies psychotic episodes as observed in patients with some types of bipolar disorder and schizophrenia. The…”
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20
Deletion of dopamine D 2 receptors from parvalbumin interneurons in mouse causes schizophrenia-like phenotypes
Published in Proceedings of the National Academy of Sciences - PNAS (27-03-2018)“…Excessive dopamine neurotransmission underlies psychotic episodes as observed in patients with some types of bipolar disorder and schizophrenia. The…”
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