Search Results - "Burgess, Zach"
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Hypoxic activation of AMPK is dependent on mitochondrial ROS but independent of an increase in AMP/ATP ratio
Published in Free radical biology & medicine (15-05-2009)“…AMP-activated protein kinase (AMPK) is a sensor of cellular energy status found in metazoans that is known to be activated by stimuli that increase the…”
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Mitochondrial Complex III-generated Oxidants Activate ASK1 and JNK to Induce Alveolar Epithelial Cell Death following Exposure to Particulate Matter Air Pollution
Published in The Journal of biological chemistry (23-01-2009)“…We have previously reported that airborne particulate matter air pollution (PM) activates the intrinsic apoptotic pathway in alveolar epithelial cells through…”
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Journal Article -
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Ambient particulate matter accelerates coagulation via an IL-6-dependent pathway
Published in The Journal of clinical investigation (01-10-2007)“…The mechanisms by which exposure to particulate matter increases the risk of cardiovascular events are not known. Recent human and animal data suggest that…”
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Proapoptotic Noxa is required for particulate matter-induced cell death and lung inflammation
Published in The FASEB journal (01-07-2009)“…Elevated ambient levels of particulate matter air pollution are associated with excess daily mortality, largely attributable to increased rates of…”
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Journal Article