Search Results - "Burgess, Michael"

From ‘trust us’ to participatory governance: Deliberative publics and science policy by Burgess, Michael M.

“…The last 20 years have seen a shift from the view that publics need to be educated so that they trust science and its governance to the recognition that…”
Get full text

Soil Erosion Threatens Food Production by Pimentel, David, Burgess, Michael

“…Since humans worldwide obtain more than 99.7% of their food (calories) from the land and less than 0.3% from the oceans and aquatic ecosystems, preserving…”
Get full text

On spectral evolution and temporal binning in gamma-ray bursts by Burgess, J. Michael

“…The understanding of the prompt γ-ray spectra of gamma-ray bursts (GRBs) is of great importance to correctly interpret the physical mechanisms that produce the…”
Get full text

Integrated proteomic analysis of post-translational modifications by serial enrichment by Mertins, Philipp, Qiao, Jana W, Patel, Jinal, Udeshi, Namrata D, Clauser, Karl R, Mani, D R, Burgess, Michael W, Gillette, Michael A, Jaffe, Jacob D, Carr, Steven A

“…A mass spectrometry–based method using serial enrichments of different post-translational modifications (SEPTM) enables high-coverage proteomic analysis of…”
Get full text

Quantitative, multiplexed workflow for deep analysis of human blood plasma and biomarker discovery by mass spectrometry by Keshishian, Hasmik, Burgess, Michael W, Specht, Harrison, Wallace, Luke, Clauser, Karl R, Gillette, Michael A, Carr, Steven A

“…This protocol describes the deep-scale analysis of the blood plasma proteome. By combining abundant protein depletion, sample multiplexing with isobaric…”
Get full text

Narratives in Public Deliberation: Empowering Gene Editing Debate with Storytelling by Chen, Kaiping, Burgess, Michael M.

“…Gene editing in the environment must consider uncertainty about potential benefits and risks for different populations and under different conditions. There…”
Get full text

Taking the band function too far: a tale of two α's by Burgess, J. Michael, Ryde, Felix, Yu, Hoi-Fung

“…The long standing problem of identifying the emission mechanism operating in gamma-ray bursts (GRBs) has produced a myriad of possible models that have the…”
Get full text

Multiplexed, Quantitative Workflow for Sensitive Biomarker Discovery in Plasma Yields Novel Candidates for Early Myocardial Injury by Keshishian, Hasmik, Burgess, Michael W., Gillette, Michael A., Mertins, Philipp, Clauser, Karl R., Mani, D.R., Kuhn, Eric W., Farrell, Laurie A., Gerszten, Robert E., Carr, Steven A.

“…We have developed a novel plasma protein analysis platform with optimized sample preparation, chromatography, and MS analysis protocols. The workflow, which…”
Get full text

Quantitative, Multiplexed Assays for Low Abundance Proteins in Plasma by Targeted Mass Spectrometry and Stable Isotope Dilution by Keshishian, Hasmik, Addona, Terri, Burgess, Michael, Kuhn, Eric, Carr, Steven A.

“…Biomarker discovery produces lists of candidate markers whose presence and level must be subsequently verified in serum or plasma. Verification represents a…”
Get full text

Correlation of Computed Tomography and Positron Emission Tomography in Patients With Metastatic Gastrointestinal Stromal Tumor Treated at a Single Institution With Imatinib Mesylate: Proposal of New Computed Tomography Response Criteria by CHOI, Haesun, CHARNSANGAVEJ, Chuslip, FARIA, Silvana C, MACAPINLAC, Homer A, BURGESS, Michael A, PATEL, Shreyaskumar R, CHEN, Lei L, PODOLOFF, Donald A, BENJAMIN, Robert S

“…Response Evaluation Criteria in Solid Tumors (RECIST) are insensitive in evaluating gastrointestinal stromal tumors (GISTs) treated with imatinib. This study…”
Get full text

We Should Desist Using RECIST, at Least in GIST by BENJAMIN, Robert S, CHOI, Haesun, MACAPINLAC, Homer A, BURGESS, Michael A, PATEL, Shreyaskumar R, CHEN, Lei L, PODOLOFF, Donald A, CHARNSANGAVEJ, Chuslip

“…Response Evaluation Criteria in Solid Tumors (RECIST) are insensitive in evaluating imatinib-treated gastrointestinal stromal tumors (GISTs). Response by Choi…”
Get full text

Phase 1 study of anti-CD47 monoclonal antibody CC-90002 in patients with relapsed/refractory acute myeloid leukemia and high-risk myelodysplastic syndromes by Zeidan, Amer M., DeAngelo, Daniel J., Palmer, Jeanne, Seet, Christopher S., Tallman, Martin S., Wei, Xin, Raymon, Heather, Sriraman, Priya, Kopytek, Stephan, Bewersdorf, Jan Philipp, Burgess, Michael R., Hege, Kristen, Stock, Wendy

“…CC-90002 is an anti-CD47 antibody that inhibits CD47-SIRPα interaction and enables macrophage-mediated killing of tumor cells in hematological cancer cell…”
Get full text

Gene dosage effect of CUX1 in a murine model disrupts HSC homeostasis and controls the severity and mortality of MDS by An, Ningfei, Khan, Saira, Imgruet, Molly K., Gurbuxani, Sandeep K., Konecki, Stephanie N., Burgess, Michael R., McNerney, Megan E.

“…Monosomy 7 (−7) and del(7q) are high-risk cytogenetic abnormalities common in myeloid malignancies. We previously reported that CUX1, a homeodomain-containing…”
Get full text

Community recommendations on biobank governance: Results from a deliberative community engagement in California by Dry, Sarah M, Garrett, Sarah B, Koenig, Barbara A, Brown, Arleen F, Burgess, Michael M, Hult, Jen R, Longstaff, Holly, Wilcox, Elizabeth S, Madrigal Contreras, Sigrid Karina, Martinez, Arturo, Boyd, Elizabeth A, Dohan, Daniel

“…United States-based biorepositories are on the cusp of substantial change in regulatory oversight at the same time that they are increasingly including samples…”
Get full text

KRAS Allelic Imbalance Enhances Fitness and Modulates MAP Kinase Dependence in Cancer by Burgess, Michael R., Hwang, Eugene, Mroue, Rana, Bielski, Craig M., Wandler, Anica M., Huang, Benjamin J., Firestone, Ari J., Young, Amy, Lacap, Jennifer A., Crocker, Lisa, Asthana, Saurabh, Davis, Elizabeth M., Xu, Jin, Akagi, Keiko, Le Beau, Michelle M., Li, Qing, Haley, Benjamin, Stokoe, David, Sampath, Deepak, Taylor, Barry S., Evangelista, Marie, Shannon, Kevin

“…Investigating therapeutic “outliers” that show exceptional responses to anti-cancer treatment can uncover biomarkers of drug sensitivity. We performed…”
Get full text

The creatine kinase pathway is a metabolic vulnerability in EVI1-positive acute myeloid leukemia by Fenouille, Nina, Bassil, Christopher F, Ben-Sahra, Issam, Benajiba, Lina, Alexe, Gabriela, Ramos, Azucena, Pikman, Yana, Conway, Amy S, Burgess, Michael R, Li, Qing, Luciano, Frédéric, Auberger, Patrick, Galinsky, Ilene, DeAngelo, Daniel J, Stone, Richard M, Zhang, Yi, Perkins, Archibald S, Shannon, Kevin, Hemann, Michael T, Puissant, Alexandre, Stegmaier, Kimberly

“…Transcriptomic and metabolic profiling reveals that the creatine kinase pathway is essential for growth of acute myeloid leukemias expressing the transcription…”
Get full text

Recognizing Salinity Threats in the Climate Crisis by Lee, Carol Eunmi, Downey, Kala, Colby, Rebecca Smith, Freire, Carolina A, Nichols, Sarah, Burgess, Michael N, Judy, Kathryn J

“…Abstract Climate change is causing habitat salinity to transform at unprecedented rates across the globe. While much of the research on climate change has…”
Get full text

Public values and guiding principles for implementing epitope compatibility in kidney transplantation allocation criteria: results from a Canadian online public deliberation by Slomp, Caitlin, Edwards, Louisa, Burgess, Michael, Sapir-Pichhadze, Ruth, Keown, Paul, Bryan, Stirling

“…Epitope compatibility in deceased donor kidney allocation is an emerging area of precision medicine (PM), seeking to improve compatibility between donor…”
Get full text

Simplified and Efficient Quantification of Low-abundance Proteins at Very High Multiplex via Targeted Mass Spectrometry by Burgess, Michael W., Keshishian, Hasmik, Mani, D.R., Gillette, Michael A., Carr, Steven A.

“…Liquid chromatography–multiple reaction monitoring mass spectrometry (LC-MRM-MS) of plasma that has been depleted of abundant proteins and fractionated at the…”
Get full text

Preclinical efficacy of MEK inhibition in Nras-mutant AML by Burgess, Michael R., Hwang, Eugene, Firestone, Ari J., Huang, Tannie, Xu, Jin, Zuber, Johannes, Bohin, Natacha, Wen, Tiffany, Kogan, Scott C., Haigis, Kevin M., Sampath, Deepak, Lowe, Scott, Shannon, Kevin, Li, Qing

“…Oncogenic NRAS mutations are highly prevalent in acute myeloid leukemia (AML). Genetic analysis supports the hypothesis that NRAS mutations cooperate with…”
Get full text