Search Results - "Burgess, Eleanor"
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Role of Sodium-Dependent Vitamin C Transporter-2 and Ascorbate in Regulating the Hypoxic Pathway in Cultured Glioblastoma Cells
Published in Journal of cellular biochemistry (09-10-2024)“…The most common and aggressive brain cancer, glioblastoma, is characterized by hypoxia and poor survival. The pro-tumour transcription factor,…”
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Limited Association Between Ascorbate Concentrations and Vitamin C Transporters in Renal Cell Carcinoma Cells and Clinical Samples
Published in Cellular physiology and biochemistry (02-10-2021)“…Maintenance of whole-body ascorbate levels and distribution is mediated via sodium-dependent vitamin C transporters (SVCTs). The kidney is one of a few organs…”
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Ascorbate content of clinical glioma tissues is related to tumour grade and to global levels of 5-hydroxymethyl cytosine
Published in Scientific reports (01-09-2022)“…Gliomas are incurable brain cancers with poor prognosis, with epigenetic dysregulation being a distinctive feature. 5-hydroxymethylcytosine (5-hmC), an…”
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Provider perspectives on the integration of patient-reported outcomes in an electronic health record
Published in JAMIA open (01-04-2019)“…Integrating patient-reported outcomes (PROs) into electronic health records (EHRs) can improve patient-provider communication and delivery of care. However,…”
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The Role of 2-Oxoglutarate Dependent Dioxygenases in Gliomas and Glioblastomas: A Review of Epigenetic Reprogramming and Hypoxic Response
Published in Frontiers in oncology (25-03-2021)“…Gliomas are a heterogeneous group of cancers that predominantly arise from glial cells in the brain, but may also arise from neural stem cells, encompassing…”
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Communication Hotspots: How Infrastructure Shapes People's Health
Published in Health communication (01-03-2021)“…Informed by communication infrastructure theory (CIT) and the social capital approach to health, this study focused on the role played by communication…”
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Increased Ascorbate Content of Glioblastoma Is Associated With a Suppressed Hypoxic Response and Improved Patient Survival
Published in Frontiers in oncology (28-03-2022)“…Glioblastoma multiforme is a challenging disease with limited treatment options and poor survival. Glioblastoma tumours are characterised by hypoxia that…”
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Low Vitamin C Status in Patients with Cancer Is Associated with Patient and Tumor Characteristics
Published in Nutrients (05-08-2020)“…Vitamin C (ascorbate) acts as an antioxidant and enzyme cofactor, and plays a vital role in human health. Vitamin C status can be affected by illness, with low…”
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Gene and Protein Expression Is Altered by Ascorbate Availability in Murine Macrophages Cultured under Tumour-Like Conditions
Published in Antioxidants (11-03-2021)“…Tumour-associated macrophages (TAMs) are ubiquitously present in tumours and commonly associated with poor prognosis. In immune cells, ascorbate affects…”
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Sensi-steps: Using Patient-Generated Data to Prevent Post-stroke Falls
Published in AMIA ... Annual Symposium proceedings (2017)“…We present Sensi-steps, an application using patient-generated data (PGD) to prevent falls for geriatric and especially poststroke patients. The Sensi-steps…”
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Circulating Spike Protein Detected in Post–COVID-19 mRNA Vaccine Myocarditis
Published in Circulation (New York, N.Y.) (14-03-2023)“…Cases of adolescents and young adults developing myocarditis after vaccination with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-targeted mRNA…”
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Care Managers and Role Ambiguity: The Challenges of Supporting the Mental Health Needs of Patients with Chronic Conditions
Published in Computer supported cooperative work (01-02-2021)“…As U.S. healthcare organizations transition to value-based healthcare, they are increasingly focusing on supporting patients who have difficulties managing…”
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Circulating Spike Protein Detected in Post–COVID-19 mRNA Vaccine Myocarditis
Published in Circulation (New York, N.Y.) (04-01-2023)Get full text
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Collaborative Self-Management of Depression
Published 01-01-2021“…Depression is a challenging mental illness that requires individuals to manage their moods and emotions over time. While past mental health literature…”
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Dissertation -
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Immunogenicity of 2 therapeutic mosaic HIV-1 vaccine strategies in individuals with HIV-1 on antiretroviral therapy
Published in npj vaccines (23-05-2024)“…Mosaic HIV-1 vaccines have been shown to elicit robust humoral and cellular immune responses in people living with HIV-1 (PLWH), that had started…”
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The last resort requirement under REACH: From principle to practice
Published in Regulatory toxicology and pharmacology (01-02-2024)“…REACH (Registration, Evaluation, Authorisation and Restriction of Chemicals) is a European Union regulation that aims to protect human health and the…”
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The role of 2-oxoglutarate dependent dioxygenases in gliomas and glioblastomas: hypoxic response and epigenetic reprogramming
Published 25-03-2021“…Gliomas are a heterogeneous group of cancers that predominantly arise from glial cells in the brain, but may also arise from neural stem cells, encompassing…”
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Introducing Meinder, De Jong, Storyteller
Published in Elementary English Review (01-01-1955)Get full text
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Aristocrats: Caroline, Emily, Louisa and Sarah Lennox 1740-1832
Published in History Ireland (01-07-1995)Get full text
Book Review