Search Results - "Burger, Scott R."

Potency assay development for cellular therapy products: an ISCT review of the requirements and experiences in the industry by Bravery, Christopher A, Carmen, Jessica, Fong, Timothy, Oprea, Wanda, Hoogendoorn, Karin H, Woda, Juliana, Burger, Scott R, Rowley, Jon A, Bonyhadi, Mark L, Van't Hof, Wouter

“…Abstract The evaluation of potency plays a key role in defining the quality of cellular therapy products (CTPs). Potency can be defined as a quantitative…”
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National Blood Foundation 2021 Research and Development summit: Discovery, innovation, and challenges in advancing blood and biotherapies by Holmberg, Jerry A., Henry, Stephen M., Burnouf, Thierry, Devine, Dana, Marschner, Susanne, Boothby, Thomas C., Burger, Scott R., Chou, Stella T., Custer, Brian, Blumberg, Neil, Siegel, Donald L., Spitalnik, Steven L.

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Validation of short-term handling and storage conditions for marrow and peripheral blood stem cell products by Kao, Grace S., Kim, Haesook T., Daley, Heather, Ritz, Jerome, Burger, Scott R., Kelley, Linda, Vierra-Green, Cynthia, Flesch, Sue, Spellman, Stephen, Miller, John, Confer, Dennis

“…BACKGROUND: Allogeneic hematopoietic stem cell transplants from unrelated donors are routinely used in the treatment of patients with hematologic malignancies…”
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Developing assays to address identity, potency, purity and safety: cell characterization in cell therapy process development by Carmen, Jessica, Burger, Scott R, McCaman, Michael, Rowley, Jon A

“…A major challenge to commercializing cell-based therapies is developing scalable manufacturing processes while maintaining the critical quality parameters…”
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Hyaluronan Synthase Elevation in Metastatic Prostate Carcinoma Cells Correlates with Hyaluronan Surface Retention, a Prerequisite for Rapid Adhesion to Bone Marrow Endothelial Cells by Simpson, Melanie A., Reiland, Jane, Burger, Scott R., Furcht, Leo T., Spicer, Andrew P., Oegema, Theodore R., McCarthy, James B.

“…Bone marrow is the primary site of metastasis in patients with advanced stage prostate cancer. Prostate carcinoma cells metastasizing to bone must initially…”
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A changing time: the International Society for Cellular Therapy embraces its industry members by Deans, Robert, Gunter, Kurt C, Allsopp, Timothy, Bonyhadi, Mark, Burger, Scott R, Carpenter, Melissa, Clark, Tara, Cox, Charles S, Driscoll, Dawn, Field, Ed, Huss, Ralf, Lardenoije, René, Lodie, Tracey A, Mason, Chris, Neubiser, Richard, Rasko, John E.J, Rowley, Jon, Maziarz, Richard T

“…Abstract The last decade has seen a dramatic rise in the development of new cellular therapeutics in a wide range of indications. There have been acceptable…”
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Non-frozen preservation of umbilical cord blood by Koenigbauer, Ulrike F., Burger, Scott R., McCullough, Jeffrey

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Retroviral transduction and expansion of peripheral blood lymphocytes for the treatment of mucopolysaccharidosis type II, Hunter's syndrome by Stroncek, David F., Hubel, Allison, Shankar, Raji A., Burger, Scott R., Pan, Dao, McCullough, Jeffrey, Whitley, Chester B.

“…BACKGROUND: Gene therapy using autologous peripheral blood lymphocytes (PBLs) has been used to produce adenosine deaminase with which to treat patients with…”
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Cellular engineering of HSV-tk transduced, expanded T lymphocytes for graft-versus-host disease management by Burger, Scott R, Kadidlo, Diane M, Basso, Lisa, Bostrom, Nancy, Orchard, Paul J

“…Engineering donor T lymphocytes with inducible 'suicide genes', such as herpes simplex virus thymidine kinase, has potential to improve safety and efficacy in…”
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HPC viability measurement: trypan blue versus acridine orange and propidium iodide by Mascotti, K., McCullough, J., Burger, S.R.

“…BACKGROUND: A reliable, validated method for rapidly determining HPC viability is essential for clinical cell engineering. STUDY DESIGN AND METHODS: A…”
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Current regulatory issues in cell and tissue therapy by Burger, S.R.

“…Cell-based therapies have grown dramatically in power and scope in recent years. Once limited to blood and BM transplantation, these therapies now encompass…”
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Design and operation of a current good manufacturing practices cell-engineering laboratory by Burger, Scott R.

“…Medical centers and biotechnology companies active in cellular and gene therapy increasingly are working to design and build clinical laboratories capable of…”
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Improved progenitor assay standardization using peripheral blood progenitor cells from a donor treated with granulocyte-colony-stimulating factor by Burger, S.R., Kadidlo, D., McCullough, J.

“…Progenitor assays are the principal method for evaluating hematopoietic cell function. The magnitude of assay variability and the assay steps contributing to…”
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The above letter was sent to Burger et al., who offered the following reply by Burger, Scott R., Fautsch, Susan K., Stroncek, David F., McCullough, Jeffrey

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Integration of concurrent collection of plasma into a plateletpheresis program by Burger, S R, Thomas, B T, Grishaber, J E

“…We have reviewed our initial experience with a program of concurrent collection of plasma (CCP) during plateletpheresis, which was instituted to increase the…”
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