Search Results - "Burger, Richard M"
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Protection of melanized Cryptococcus neoformans from lethal dose gamma irradiation involves changes in melanin's chemical structure and paramagnetism
Published in PloS one (22-09-2011)“…Certain fungi thrive in highly radioactive environments including the defunct Chernobyl nuclear reactor. Cryptococcus neoformans (C. neoformans), which uses…”
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Specific Function of the Met-Tyr-Trp Adduct Radical and Residues Arg-418 and Asp-137 in the Atypical Catalase Reaction of Catalase-Peroxidase KatG
Published in The Journal of biological chemistry (26-10-2012)“…Catalase activity of the dual-function heme enzyme catalase-peroxidase (KatG) depends on several structural elements, including a unique adduct formed from…”
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Cleavage of Nucleic Acids by Bleomycin
Published in Chemical reviews (07-05-1998)“…The reactions enabling iron-bleomycin to attack DNA are discussed, as well as the events that complete the degradation of DNA…”
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Exchangeable proton ENDOR as a probe of the redox-active iron center in activated bleomycin and ferric bleomycin
Published in Dalton transactions : an international journal of inorganic chemistry (10-10-2017)“…Activated bleomycin (ABLM) is a drug-Fe(iii)-hydroperoxide complex kinetically competent in DNA attack (via H4' abstraction). This intermediate is relatively…”
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Superoxide protects Escherichia coli from bleomycin mediated lethality
Published in Journal of inorganic biochemistry (01-09-2009)“…Superoxide and its products, especially hydroxyl radical, were recently proposed to be instrumental in cell death following treatment with a wide range of…”
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Role of Superoxide in Catalase-Peroxidase-Mediated Isoniazid Action against Mycobacteria
Published in Antimicrobial Agents and Chemotherapy (01-03-1998)“…Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Cryogenic Photolysis of Activated Bleomycin to Ferric Bleomycin
Published in The journal of physical chemistry. B (19-10-2006)“…Activated bleomycin (ABLM) is a drug−Fe(III)−hydroperoxide complex kinetically competent in DNA attack (via H4‘ abstraction). This intermediate is relatively…”
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Stimulation of iron(II) bleomycin activity by phosphate-containing compounds
Published in Biochemistry (Easton) (01-07-1985)“…Orthophosphate and phosphate derivatives including pyrophosphate, hexametaphosphate, ATP, ADP, and inositol hexaphosphate enhance the extent of DNA degradation…”
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Oxygen isotope effect on activated bleomycin stability
Published in Journal of the American Chemical Society (1995)Get full text
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ENDOR Determination of the Distance between Bleomycin-Bound Iron and 19F of 2‘-Fluorocytidine in a DNA Target Sequence
Published in Journal of the American Chemical Society (19-12-2001)Get full text
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Efficacy of cobalt chelates in the rabbit eye model for epithelial herpetic keratitis
Published in Cornea (01-09-1998)“…A new class of antiviral agent, cobalt chelates (the CTC series), was evaluated for treating epithelial herpetic keratitis, consequent stromal disease being…”
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Q-band Electron Nuclear Double Resonance of Ferric Bleomycin and Activated Bleomycin Complexes with DNA: Fe(III) Hyperfine Interaction with 31P and DNA-Induced Perturbation to Bleomycin Structure
Published in Journal of the American Chemical Society (11-02-1998)“…Q-band electron nuclear double resonance (ENDOR) has measured anisotropic, distance-dependent dipolar hyperfine couplings from iron in ferric bleomycin…”
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5'-Nucleotidase from smooth muscle of small intestine and from brain. Inhibition by nucleotides
Published in Biochemistry (Easton) (01-06-1975)“…5'-Nucleotidase prepared from muscle of small intesting of pig is strongly inhibited by nucleoside di- and triphosphates and their phosphonate analogs…”
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DNA degradation by manganese(II)-bleomycin plus peroxide
Published in Inorganic chemistry (01-07-1984)Get full text
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Preparation and Properties of 5'-Nucleotidase from Smooth Muscle of Small Intestine
Published in The Journal of biological chemistry (10-12-1970)“…5'-Nucleotidase prepared from smooth muscle is strongly inhibited by ADP. This inhibition is much stronger than the previously described inhibition of…”
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Toluene-Treated Escherichia coli Replicate only that DNA which was about to be Replicated in vivo
Published in Proceedings of the National Academy of Sciences - PNAS (01-09-1971)“…DNA density-transfer experiments with Escherichia coli strain B/r indicate that the DNA synthesized from exogenous substrates after treatment with toluene is…”
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ENDOR Determination of the Distance between Bleomycin-Bound Iron and 19 F of 2‘-Fluorocytidine in a DNA Target Sequence
Published in Journal of the American Chemical Society (19-12-2001)Get full text
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Effect of Nalidixic Acid on DNA Replication by Toluene-Treated Escherichia coli
Published in Proceedings of the National Academy of Sciences - PNAS (01-07-1973)“…Nalidixic acid inhibits DNA synthesis in toluene-treated E. coli, strain B/r, as it is well known to do in vivo. Both semiconservative and repair syntheses are…”
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